Overview Online Download Documentation Contacts Splign is a utility for computing cDNA-to-Genomic, or spliced sequence alignments. At the heart of the program is a compartmentization algorithm which identifies possible gene duplications, and a refined alignment algorithm recognizing introns and splice signals. Please follow one of the links below or navigate using the menu bar at the top of this page. Download a stand-alone application if you need to compute alignments for a large number of sequences. If you have a small number of sequences to align or just want to try out, click here to submit an online job. Read the documentation. References: Y.Kapustin, A.Souvorov, T.Tatusova and D.Lipman. Splign: algorithms for computing spliced alignments with identification of paralogs. Biology Direct, May 2008. Y.Kapustin, A.Souvorov and T.Tatusova. Splign - a Hybrid Approach To Spliced Alignments. RECOMB 2004 - Currents in Computational Molecular Biology. p.741. Related links: ProSplign, the tool for alignment of proteins against genomic sequences which is aware of splice signals and possible frameshifts. |Disclaimer |Privacy statement | Accessibility |