Daniela Malide from the Light Microscopy Core teams up with Jean Yves Metais and Cynthia Dunbar from the Molecular Hematopoiesis Section to develop a fluorescence marking methodology for tracing the clonal history of hematopoietic stem and progenitor cells in live tissue. Read the full article in the December 20, 2012 Blood
NHLBI Stadtman Investigator Susan Harbison is featured as one of Genome Technology’s 7th annual Young Investigators for her studies on how genetic variation and the environment influence sleep and other complex traits in fruit flies.
NIH ranks #1 in the 2012 edition of Universum’sTop 100 Ideal Employers in the Natural Sciences. Read more, including an interview with NHLBI investigator Justin Taraska, here.
The mission of the NHLBI Division of Intramural Research (DIR) is to perform robust scientific and clinical research leading to a better understanding of biology and clinical pathology. To attain this goal, we have built a strong basic science foundation and coupled it closely with innovative technology development and outstanding clinical research both at the NIH Clinical Center and in partnership with local hospitals.
The purview of our research is broad, encompassing investigations into the basic principles of molecular, cellular, and organ-level biology and their relationship to disease. Some current areas of fundamental interest include single molecule structure; protein assembly; molecular and cell biology; cell signaling and motility; membrane trafficking; physiology; systems biology; engineering and technology development. Insights into disease mechanisms derived from basic studies form the basis for translational research into new diagnostic and therapeutic approaches.
DIR investigators also conduct concept-based clinical studies in the areas of interventional and surgical cardiology; pulmonary medicine; sickle cell anemia; bone marrow transplant; and hematologic disorders. The Center for Population Studies located in Framingham Massachusetts and associated with the Framingham Heart Study focuses on Epidemiology of cardiovascular disease.
Providing state-of-the-art training in basic, translational, and clinical research for the next generation of scientific and clinical leaders is a high priority. This program provides opportunities for scientists and trainees to work together towards a better understanding of molecular machines, the cell, the body, and ultimately the treatment of human diseases.