Center for BioMedical Informatics and Information Technology (CBIIT) 7 Resources
1. Cancer Bioinformatics Infrastructure Objects (caBIO)
Conducting biomedical research requires access to experimental data, as well as associated molecular annotations. Annotations providing detailed information on the molecular origin, biological process, and genetic alterations can provide important...
2. Cancer Molecular Analysis Project (CMAP)
CMAP is designed to enable researchers to identify and evaluate molecular targets in cancer. Four category headings allow researchers to quickly find information.
Molecular Profiles: Find the 50 genes with the highest or...
3. Experiment Design Tools
NCI-provided portal to tools for designing microarray experiments.Users are allowed to add tools and comment on the available tools.Resources include:
Cancer Genome Anatomy Project: identify genes for array experiments...
4. Inventory of Digital Information Resources for Researchers
This living inventory is designed to provide the scientific, biomedical informatics and Health IT communities with access to data from clinical research, biospecimens, in vivo images, molecular signatures, and population studies of multiple cancer...
5. Molecular Analysis of Cancer - Data Analysis Tools
NCI-provided portal to multiple analysis programs for microarraydata. Permits the exchange of tools and discussion of their utility.Tools include:
XML-DBMS: middleware for transferring data between XML documents and relational...
6. Molecular Analysis of Cancer - Data Management
NCI-provided portal to computer-based tools for managing microarrayexperimental data. Users are allowed to add tools and comment on theavailable tools. Resources include:
NHGRI Array DB 2.1: relational database provides storage...
7. NCI's Enterprise Vocabulary Services (EVS)
NCI Enterprise Vocabulary Services (EVS) provides resources and services to meet NCI needs for controlled terminology. NCI needs for terminology...
Center for Cancer Research (CCR) 8 Resources
1. Cancer Chromosome Aberration Project (CGAP)
An initiative to integrate cytogenetic and physical maps of thehuman genome. Bacterial Artificial Chromosomes (BAC) clones, mapped ata resolution of 1-2 MB across all human chromosomes, will be part of adatabase designed to:
...
2. CCR Research Directory
The CCR Research Directory provides an overview of each Branch, Laboratory, and Program as well as links to individual Web sites for Principal Investigators, Staff Clinicians, and Staff Scientists. The Directory is organized into 3 indexes: ...
3. Enhanced NCI Database Browser 2.1
Search more than 250,000 compounds from the open NCI database. Features include:
Substructure search capabilities (e.g., search for H-bond acceptor/donor)
Expanded search criteria (log P [calc.], complexity, data...
4. Genomics and Bioinformatics Software Tools
MedMine: Searches and organizes the biomedical literature on genes, gene-gene relationships, and gene-drug relationships. MatchMiner: Translates among gene identifier types for lists of hundreds or thousands of genes. GoMiner: Addresses the...
5. Laser Capture Microdissection (LCM)
Laser capture microdissection (LCM) technology uses laser-activated film (polymer) to capture pure populations of cells from frozen or paraffin-embedded tissue sections for molecular analysis. Presently, the LCM Core Facility for the application...
6. Neuro-Oncology Consulting Service
This service provides:
Expert consultation services from neuro-oncologists regarding diagnosis, management, and treatment of adult patients with primary and metastatic tumors of the central nervous system.
7. Tissue Array Research Program (TARP)
The Tissue Array Research Program (TARP) distributes multi-tumor tissue microarray slides and related technology to cancer researchers. This enabling technology will help expedite discovery of novel targets important in cancer treatment by...
8. Understanding Cancer Series
The Understanding Cancer Series includes graphic-rich tutorials foreducational use by life science teachers, medical professionals, and the interested public. Each tutorial is available in English or Spanishand in PDF and PowerPoint formats that...
Division of Cancer Biology (DCB) 8 Resources
1. Chemical Carcinogen Reference Standards Synthesis Program
Providing chemical reference standards for chemical carcinogenesis and prevention research. 70 chemical carcinogens (polycyclics, nitrosamines, and heterocyclic amines), chemopreventive agents and chemical metabolites are...
2. Chernobyl Tissue Bank, The
The Chernobyl Tissue Bank (CTB) is an international repository resource that supports studies on the health consequences of the Chernobyl accident. The project is funded by the NCI and other international partners and involves active participation...
3. eMICE Web Site – Electronic Models Information, Communication, and Education
An Internet resource providing extensive information about experimental and spontaneous animal models for cancer research, including:
Information on animal...
4. Integrative Cancer Biology Program (ICBP) Website
NCI's extramural Integrative Cancer Biology Program (ICBP) focuses on the analysis of cancer as a complex biological system. The program brings clinical and basic cancer researchers together with researchers from mathematics, physics,...
5. NCI Cancer Models Database
A database of mouse, rat, and other animal models of human cancers submitted by cancer researchers that contains information about:
Constructing models
Genetic description
...
6. NCI's Mouse Repository
A mouse repository/distribution resource at the NCI-Frederick Cancer Research Center that:
Supplies mouse cancer models and associated strains and information pertaining to them to the scientific community
Accepts...
7. Registry of Tumors in Lower Animals (RTLA)
A diagnostic center, specimen depository, and information clearinghouse that provides:
Slides of neoplasms and related diseases among reptiles, amphibians, fish, sharks, mollusks, arthropods, echinoderms, and coral
...
8. Synchrotron X-ray Crystallography Beamline for Macromolecular Structure Determination
Providing dedicated access for NCI researchers to a state-of-the-art synchrotron X-ray beamline for determining cancer relevant macromolecular structures using X-ray crystallography. The facility is located at the Advanced Photon Source of Argonne...
Division of Cancer Control and Population Sciences (DCCPS) 32 Resources
1. Annual Report to the Nation on the Status of Cancer
The National Cancer Institute, the American Cancer Society, the Centers for Disease Control and Prevention, and the North American Association of Central Cancer Registries collaborate to provide an annual update on cancer occurrence and trends...
2. California Health Interview Survey
The California Health Interview Survey (CHIS) is a telephone survey that provides population-based, standardized health-related data from households selected from all 58 counties in the state. Fielded for the first time in 2001 as a biennial...
3. Cancer Control P.L.A.N.E.T.
Cancer control planners, program staff, and researchers have the same goals: to reduce cancer risk, the number of new cancer cases, and the number of deaths from cancer, as well as enhance the quality...
4. Cancer Family Registries for Breast and Colon Cancer
The Breast Cancer Family Registry (Breast CFR) and the Colon Cancer Family Registry (Colon CFR) were established by the National Cancer Institute (NCI) as a unique resource for investigators to use in conducting studies on the genetics and...
5. Cancer Genetics Network (CGN)
The Cancer Genetics Network (CGN) is a resource for investigators conducting research on the genetic basis of human cancer susceptibility; integration of this information into medical practice; and behavioral, ethical, and public health issues...
6. Cancer Mortality Maps & Graphs Web Site
The Cancer Mortality Maps website provides dynamically generated maps for the time period 1950-2004 (1970-2004 only for Blacks). Both mortality rates and maps are generated at the time of the request, which means that it may occasionally take...
7. Cancer Query Systems
The Cancer Query Systems (CANQUES) are data retrieval applications that provide access to cancer statistics stored in online databases. These systems do not perform calculations, they display reports using databases of statistics generated by...
8. Cancer Risk Prediction Resources
Accurately assessing cancer risk in average- and high-risk individuals is an important component to controlling the suffering and death due to cancer. Cancer risk prediction models provide an important approach to assessing risk and susceptibility...
9. Cancer Survivor Prevalence Statistics
Cancer survivor prevalence statistics based on data from the NCI's Surveillance Epidemiology and End Results (SEER) Program are available. Cancer survivor prevalence represents the proportion (or number) of people alive on a certain day who...
10. Cancer Trends Progress Report
The Cancer Trends Progress Report was designed to help the nation review past efforts and plan future ones. The public can use the report to better understand the nature and results of strategies to fight cancer. Researchers, clinicians, and...
11. DevCan Software Program
Statistical models are used to compute the probability of being diagnosed or dying of cancer from birth or conditional on a certain age. DevCan takes cross-sectional counts of incident cases from the standard areas of the Surveillance,...
12. Diet History Questionnaire
The Diet History Questionnaire (DHQ) is a freely available food frequency questionnaire (FFQ) developed by staff at the Risk Factor Monitoring and Methods Branch (RFMMB). It can be used by researchers, clinicians, or teachers without ...
13. Diet*Calc
The Diet*Calc software is used to analyze the Diet History Questionnaire data files. It interprets the DHQ data to provide nutrient and food group intake estimates.
14. Dietary Assessment Calibration/Validation (DACV) Register
Compares dietary intake estimates from two or more dietary assessment methods, including:
Food records or diaries, dietary recalls
Food frequency questionnaires (FFQ's), dietary histories, observed intakes
...
15. Directory of Products Developed through Multimedia Technology Health Communication Grants for Small Businesses
NCI's Health Communications and Informatics Research Branch, in the Division of Cancer Control and Population Sciences, works with the SBIR Development Center in the Office of the NCI Director to support the funding of behavioral research. ...
16. Fast Stats
Fast Stats is an interactive tool for quick access to key SEER and US cancer statistics for major cancer sites by age, sex, race/ethnicity and data type.
Statistics are presented as graphs and tables.
17. Finding Cancer Statistics
Finding Cancer Statistics is a plain-language Web site that provides access to recent reports, datasets, and statistical tools for professionals and the general public. It includes definitions of commonly used statistics, descriptions of...
18. Geographic Information System for Breast Cancer Studies on Long Island (LI GIS)
The Geographic Information System for Breast Cancer Studies on Long Island (LI GIS) is a unique research tool combining an extensive collection of data and other geospatial resources. The LI GIS is designed primarily to study potential...
19. Glycemic Index Values Database
NCI has developed a listing of Glycemic Index (GI) values for individual foods. Food codes from the USDA Continuing Survey of Food Intakes of Individuals (CSFII) are used as a reference. The file provides GI values for those foods consumed by...
20. Health Information National Trends Survey
HINTS collects nationally representative data routinely about the American public's use of cancer-related information. The survey:
Provides updates on changing patterns, needs, and information...
21. Implementation Science
The Implementation Science Web site provides researchers and public health practitioners a single location for knowledge transfer in cancer control, including access to current research, funding opportunities, information and resources, and...
22. International Cancer Screening Network (ICSN)
The International Cancer Screening Network (ICSN) is a voluntary consortium of countries that have active population-based cancer screening programs. These programs can be national or subnational in scope, and established or pilot-based....
23. Joinpoint Regression Program
Joinpoint is statistical software for the analysis of trends using joinpoint models, that is, models like the figure below where several different lines are connected together at the "joinpoints". Cancer trends reported in NCI...
24. National Health Interview Survey (NHIS) Cancer Control Topical Module
This public use data resource, distributed by the National Center for Health Statistics (NCHS) and supported by NCI, provides:
Data collection survey instruments (questionnaires)
Field representative's flashcard...
25. SEER Data
The SEER research data include SEER incidence and population data associated by age, sex, race, year of diagnosis, and geographic areas (including SEER registry and county). A signed Research Data Agreement is required to access these data. ...
26. SEER*Prep Software
Companion system to SEER*Stat that allows cancer investigators to prepare and format their own cancer incidence, mortality, and population data.
27. SEER*Stat Software
The SEER*Stat statistical software provides a convenient, intuitive mechanism for the analysis of SEER and other cancer-related databases. It is a powerful PC tool to view individual cancer records and to produce statistics for studying the...
28. SEER-Medicare Database
whatLinks clinical data collected by the SEER registries with claimsfor health services collected by Medicare for its beneficiaries. Thesecombined datasets can be used for assessing
Patterns of care for persons with cancer...
29. Smokefree Meeting Policy
NCI recognizes that environmental tobacco smoke (ETS) is an important preventable cause of death from cancer and other illnesses and that many Americans, both adults and children, remain at significant risk from ETS exposure. To reduce cancer and...
30. Smokefree.gov
Smokefree.gov is intended to help you or someone you care about quit smoking.
Different people need different resources as they try to quit. The information and professional assistance available on this Web site can help to support both...
31. Theories Project: Improving Theories of Health Behavior
The goal of the Theories Project is to identify and carry out activities that will help develop improved theories of health behavior. Its focus is on actions that individuals can take to prevent cancer and speed its early detection. The literature...
32. Tobacco Use Supplement - Current Population Survey
The Tobacco Use Supplement to the Current Population Survey (TUS-CPS) is an NCI-sponsored survey of tobacco use that has been administered as part of the US Census Bureau's Current Population Survey in 1992-1993, 1995-1996, 1998-1999, 2000,...
Division of Cancer Epidemiology and Genetics (DCEG) 16 Resources
1. Biospecimen Inventory Processing System (BSI-II)
Designed for use in biospecimen repositories, BSI-II:
Tracks and controls the acquisition, storage, aliquoting, processing, requisition, and distribution of biological specimens
Records a complete description of...
2. Cancer Atlas
Updated atlas of cancer mortality in the U.S. (1950-1994) provides:
Mortality rates per 100,000 person-years, directly standardized using the 1970 U.S. population, calculated by race (whites: 1950-69 and 1970-94; ...
3. CaseControlIndGX
CaseControlIndGX is a MATLAB software package for maximum-likelihood analysis of case-control studies under the assumption of gene-environment independence.
Suggested reference for the CaseControlIndGX program: "Semiparametric maximum...
4. Chronic Lymphocytic Leukemia (CLL) Family Registry
This Web site provides information on families with Chronic Lymphocytic Leukemia (CLL) and encourages participation in the CLL family registry. Currently, there are over 30 kindreds (families) in the registry, with information and data collected...
5. Computerized Heterocylic Amines Resource for Research in Epidemiology of Disease (CHARRED)
The CHARRED software is:
Application developed to estimate intake of mutagenic compounds in cooked meats
It is comprised of a detailed meat cooking module within a food frequency questionnaire in conjunction with a...
6. Genewindow
Genewindow is a genome browser that lets you scroll through aparticular gene nucleotide by nucleotide, identifying SNPs and otherlandmarks, such as protein-coding segments. The Genewindow provides thefollowing:
Intuitive...
7. I-131 Dose/Risk Calculator
The materials are designed to address the concerns of Americans whowere exposed to I-131 from above-ground nuclear testing in the 1950sand early 1960s. This thyroid dose/risk calculator contains usefultools such as:
Information...
8. Interactive Risk Attributable Program
Calculates attributable risk for a variety of epidemiologic designs based on logistic modeling, and gives appropriate confidence intervals.
9. Job Modules for Occupational Questionnaires
Special questionnaires with modules designed to obtain detailed information for over 70 specific jobs or tasks, work practices, chemicals, and equipment. Addresses a wide variety of exposures. For examples of the job's modules, see...
10. KinCohort
KinCohort is an alternative to traditional cohort or case-control designs for estimating penetrance of an identified rare autosomal mutation.
Suggested reference for the KinCohort program: A marginal likelihood approach for estimating...
11. MultAssoc
MultAssoc is a MATLAB software package to test for the association of a disease with a group of Single Nucleotide Polymorphisms (SNPs) after accounting for their interaction with another group of SNPs or environmental exposures. In addition to...
12. NestedCohort
NestedCohort is an R software package for fitting Kaplan-Meier and Cox Models to estimate standardized survival and attributable risks for studies where covariates of interest are observed on only a sample of the cohort. Standard designs that can...
13. Occupational Code Assignment System (CodeSearch)
Dataset of occupation and industry job codes, providing users with an interactive method for assigning standardized industry and occupation codes to related job description titles from specific studies.
14. POWER Software
This program permits the determination of the power or sample sizefor epidemiological studies testing an effect of one factor or testingof an interaction effect between two factors. POWER V.3.0 has beenupgraded with the following new features:...
15. Publications Database from the Division of Cancer Epidemiology and Genetics
DCEG manages a program of epidemiologic, demographic, biostatistical, and population-based genetic research. Publications from the various DCEG branches can be downloaded from the division's Web Site.
16. Questionnaire Modules (QMOD)
Database of questionnaire segments with citations to articlesdescribing analysis results. Search for questionnaire modules by topic,researcher, or study title. A list of references is included to help increating new questionnaires. Topics covered...
Division of Cancer Prevention (DCP) 11 Resources
1. Analytical Validation of Biomarkers for Cancer (EDRN Associate Membership)
The Early Detection Research Network (EDRN) is a scientific consortium of the Division of Cancer Prevention that is organized to validate promising biomarkers for the early detection of and risk assessment for cancer. Researchers who have...
2. Cancer Preventive Agent Development (PREVENT) Program
The PREVENT Cancer Drug Development Program is a National Cancer Institute-supported pipeline to bring new cancer prevention agents and interventions through preclinical development towards clinical trials. (See <a...
3. Chemoprevention Agent Development Research Group
4. Early Detection Research Network (EDRN) Informatics Resources
The EDRN Informatics Center develops tools for informatics, computer-based collection, classification, storage, and analysis of knowledge. By connecting research...
5. Early Detection Research Network (EDRN) Program for Rapid, Independent Diagnostic Evaluation (PRIDE) for Cancer Biomarkers
Through its resources for serum reference samples, technologies, informatics, and reference laboratories on validation, the Early Detection Research Network (EDRN) supports investigators by helping them with rapid evaluations of the...
6. EDRN Clinial/Biological Research Tools
The NCI's Early Detection Research Network recognizes the importance of standardized, prospective collection of biologic samples in the context of clinically relevant circumstances to discover and accelerate the validation of biomarkers of...
7. National Institutes of Health Rapid Access to Interventional Development (NIH-RAID Pilot)
Promising ideas for novel therapeutic interventions can sometimes encounter roadblocks in the pipeline for preclinical development. Where private-sector capacity is limited or not available, developmental resources provided by the federal...
8. Notice of Availability of Blood Samples for Validations of Lung Cancer Biomarkers
Despite recent advances in molecular diagnostics, no specific biomarker for the early detection of lung cancer has reached the clinic. To meet this need, the Lung Cancer Biomarkers Group (LCBG) developed a requisite sample resource to validate...
9. PLCO Cancer Screening Trial - Etiology and Early Marker Studies (EEMS)
The Etiology and Early Marker Studies (EEMS) is a component of the Prostate, Lung, Colorectal, and Ovarian (PLCO) Trial. By collecting biologic materials and risk factor information from trial participants before the diagnosis of disease,...
10. Specialized Statistical Software
Downloadable collection of specialized statistical software developed by the Biometry Research Group. Programs include:
Spatial and Space-Time Scan Statistic
Conditional Logistic Regression
Cox...
11. Supportive and Palliative Care Research Sites in the CCOP Network
The National Cancer Institute has long recognized the problems independent investigators face in accruing adequate numbers of study participants to their federally funded research projects. As a result, the Division of Cancer Prevention (DCP) has...
Division of Cancer Treatment and Diagnosis (DCTD) 26 Resources
1. Acquisition of Compounds and Combinatorial Libraries
The Developmental Therapeutics Program of NCI operates an anti-cancer screening program for the benefit of the extramural research community. The program, which is operated at no cost to suppliers, accepts both natural and synthetic compounds from...
2. AIDS and Cancer Specimen Resource (ACSR)
A collection of tissues and biological fluids with associated clinical and follow-up data from patients with HIV-related malignancies. Specimens and clinical data are available for research studies, particularly those that translate basic...
3. American College of Radiology Imaging Network (ACRIN)
NCI-sponsored Cooperative Group, established to provide for a multi-center network for the systematic study and facilitation of the development and rigorous assessment of technologies relevant to diagnostic imaging of cancer. Specific objectives...
4. Biological Resources Branch (BRB) Preclinical Repository
Provides:
Human cytokines (interleukin-1, interleukin-2, basic fibroblast growth factor, vascular endothelial growth factor)
Monoclonal antibodies against human and mouse antigens
Murine and human...
5. Biological Resources Branch (BRB) Preclinical Repository
Provides:
Human cytokines (interleukin-1, interleukin-2, basic fibroblast growth factor, vascular endothelial growth factor)
Monoclonal antibodies against human and mouse antigens
Murine and human...
6. Biopharmaceutical Development Program (BDP)
BDP produces a variety of biopharmaceuticals for Phase I/II humanclinical trials or advanced preclinical animal testing. Productionservices include:
Clinical-grade biological agents from bacterial, yeast, and mammalian...
7. BRB Array Tools
BRB Array Tools is an integrated package for the visualization andstatistical analysis of DNA microarray gene expression data. Itincorporates state-of-the-art statistical methods. It was developed byprofessional statisticians in the Biometric...
8. Chemical Structure Database of Anti-Cancer Screened Compounds
Chemical structures (2D and 3D) and screening results for over 200,000 compounds tested in cancer or AIDS screens, such as:
Anti-cancer compounds grouped by mechanism of action, i.e., alkylating agents, topoisomerase I and II...
9. Clinical Data Update System (CDUS)
The Clinical Data Update System (CDUS) is the primary resource forclinical trial data for the Division of Cancer Treatment and Diagnosis(DCTD) and the Division of Cancer Prevention (DCP). CDUS reports aresubmitted for all DCTD and DCP sponsored...
10. Clinical Trials Cooperative Group Program
Supports organizations that generate and conduct new clinical trials consistent with national priorities for cancer treatment research. Emphasis is placed on definitive, randomized Phase III studies and developmental efforts preliminary to them. ...
11. Common Toxicity Criteria
CTEP plans and coordinates all aspects of clinical trials, including extramural clinical research programs, internal resources, treatment methods and effectiveness, and compilation of data pertaining to the development and evaluation of anticancer...
12. Cooperative Human Tissue Network (CHTN)
CHTN provides normal, benign, pre-cancerous and cancerous human tissue for basic and developmental studies in many areas of cancer research.
CHTN obtains tissues from routine surgical resections and autopsies.
...
13. CTEP: Developing Cancer Therapies
CTEP plans and coordinates all aspects of clinical trials. Functions and services of CTEP include:
Extramural clinical research programs
Internal resources, treatment methods and effectiveness
...
14. Database of Molecular Target Characterization of the NCI Panel of 60 Human Tumor Cell Lines
A database of quantitation of Molecular Targets within the NCIpanel of 60 human tumor cell lines. Data are available for more than250 individually measured Targets, as well as data from two microarraymeasurements. If a Target of interest has not...
15. Database of NCI Yeast Anti-Cancer Drug Screen Results
The NCI Yeast Anticancer Drug Screen has screened over 50,000 compounds from the NCI repository against a panel of yeast (Saccharomyces cerevisiae) strains.
These strains harbor 1 or 2 mutations in genes involved...
16. Database of NCI's 60 Cell Line Anti-cancer Drug Screen Results
Screening results for the ability of ~70,000 compounds to kill or inhibit the growth of a panel of 60 human tumor cell lines.
Uses the COMPARE algorithm to examine the drug sensitivity for a given compound in the 60...
17. Developmental Therapeutics Program Tumor Repository
A repository of viable experimental tumor cell lines (guinea pig, hamster, mouse, rabbit, and rat), including the 60 human tumor cell lines used for screening (such as colon, leukemia, lung, mammary, melanoma, ovarian,...
18. In Vivo Hollow Fiber Assay
Evaluation of test agents against human tumor cell lines grown in PVDF hollow fibers implanted in nude mice. The assay provides quantitative indices of drug efficacy with minimum expenditure of time and materials. It is currently being used as the...
19. Informed Consent Documents
Recommendations and an informed consent template and forms are available for use by investigators, IRBs, and patients.
20. Investigator's Handbook
Provides:
Policies and procedures concerning various aspects of therapeutic drug development and clinical use
Assistance in practical matters connected with protocol writing, submissions, reporting...
21. Laboratory Animal Production Program
Provides animals for use in scientific research: inbred mice and rats; athymic mice and rats; hybrid mice; surgical services.
22. Natural Products Repository
Over 50,000 plant samples collected in Africa and Madagascar, Central and South America, Southeast Asia and the continental United States
Over 10,000 marine invertebrates and marine algae mainly from the Indo-Pacific...
23. NCI Specimen Resource Locator
A database with query tools to locate resources such as tissuebanks and tissue procurement services with access to normal, benign,pre-cancerous and/or cancerous human tissue covering a wide variety oforgan sites. Specimens include:
...
24. Pure Chemicals Repository
A library of over 140,000 non-proprietary or "open" compounds of diverse structural types that can be requested for research purposes. These synthetic and pure natural products are for the discovery and development of new agents for the...
25. Radiolabeled Compounds Repository
Radiolabeled products and drugs, with details of drug name, 2D and 3D structure, lot number and source, and specific activity in mCi/mmol.
26. Tissue Expediter
The NCI Tissue Expediter provides information on sources of human tissue specimens for cancer research and helps researchers locate the tissue and related data they need. The Tissue Expediter is a scientist with contacts in the resources community...
Frederick Cancer Research and Development Center (NCI-FRED) 4 Resources
1. Advanced Biomedical Computing Center
Provides:
Access to proven, efficient, high-performance computers for challenging computational biology problems
Technical support, including collaborative research, algorithm development and optimization, ...
2. Application Software by Advanced Biomedical Computing Center
Sequence Analysis (GCG, Blast, Look, Phylip, Staden, and others)
Databases (MPSearch, Entrez, Cambridge (CSD), Protein (PDB), and Beilstein)
Computational Chemistry (Gaussian 94, Gamess, UniChem, AMBER,...
3. Computer Systems
High performance systems for Bioinformatics and Computational Chemistry:
IBM Power4 P690 (1x16PE/32GB, 2x32PE/64GB)
SGI MIPs Origin 3800 (1x64PE/64GB), Origin 300 (8x8PE/8GB)
SGI IA-64 Altix 3700...
4. Molecular Diagnostic Services for HIV and SIV
Measurement of viral loads from SIV-infected monkey plasma.
Additional analyses possible with prior consultation.
Office of the Director (OD) 23 Resources
1. Cancer Genome Anatomy Project (CGAP)
CGAP is an interdisciplinary program designed to understand the molecular changes that transform normal cells into cancer cells. Through its website, CGAP provides access to a wide variety of human and mouse molecular databases and also provides...
2. Cancer Information Service (CIS)
The Cancer Information Service (CIS) provides information aboutcancer to patients and their families, physicians and other healthprofessionals, and the public. The CIS's three-pronged approachutilizes information specialists that...
3. Cancer Topic Searches
Cancer Topic Searches are "packaged" literature searches of the National Library of Medicine's PUBMED database. Searches prepared by medical librarians and subject matter experts facilitate ready access to citations in the PUBMED...
4. Certificates of Confidentiality
Certificates of Confidentiality allow researchers to avoid the involuntary release of any portion of research records containing information that could be used to identify study participants. The PDF document contains background information and...
5. Community Networks Program
This resource provides an overview of the Community Networks Program, including the goals and phases of research; descriptions of the 25 projects; and descriptions and contact information about the funded institutions and principal...
6. Conducting Clinical Trials
Cancer clinical trials educational program consisting of a varietyof materials from basic information for patients, to train-the-trainercomponents for variety of organizations and professionals, includingSpanish language materials, and an online...
7. Congressional Testimony
A rundown of congressional hearings of interest and recent testimonies on cancer research.
8. Genetic Annotation Initiative (GAI)
The CGAP Genetic Annotation Initiative (GAI) is a research programto explore and apply technology for identification and characterizationof genetic variation in genes important in cancer. Available throughGAI are
The locations...
9. Informed Consent Documents
Recommendations and an informed consent template and forms are available for use by investigators, IRBs, and patients.
10. Lectures and presentations from NIH
Videocast of daily and archived seminars
11. Mammalian Gene Collection (MGC)
MGC is a trans-NIH Institute effort to generate a representativefull-length clone for all human and mouse genes, and a finite number ofrat genes, all of which are available to the research community. TheMGC project entails:
...
12. NCI Cancer Bulletin
The NCI Cancer Bulletin, a weekly electronic newsletter produced bythe National Cancer Institute (NCI) Office of Communications, is animportant part of NCI's response to its mandate under the NationalCancer Act of 1971 to educate the public and...
13. NCI Drug Dictionary
The NCI Drug Dictionary provides technical definitions, synonyms, brand names, and other names for drugs/agents used in the treatment of cancer and cancer-related conditions. Information in the NCI Drug Dictionary is from the NCI Thesaurus,...
14. NCI's List of Cancer Clinical Trials
NCI's PDQ Cancer Clinical Trials Registry provides trial descriptions for patients and health professionals for cancer clinical trials conducted in the US and internationally. The registry also includes information about sites where the trials are...
15. NewsCenter
Information for journalists:
Press releases
Background information
Downloadable audiovisual/multimedia resources
Interview transcripts
16. Patient Navigator Research Program
This resource provides an overview of the Patient Navigator Research Program, including the goals and phases of research; a description of patient navigators, descriptions of the 9 projects; and descriptions and contact information about the...
17. PDQ Database
PDQ is the National Cancer Institute's comprehensive cancer information database. It contains peer-reviewed summaries on cancer treatment, screening, prevention, genetics, and supportive care; a registry of approximately 3,500 open and...
18. Protecting Human Research Participants
This online learning module responds to the mandate requiringeducation on human subjects protection for all investigators applyingfor or receiving funds from NIH for research involving humanparticipants. The course incorporates interactive...
19. Special Populations Networks
Find links to cancer facts, health organizations, cancer survivorsgroups, and much more, for the following special populations:
Asian Pacific Islander
African American
Appalachian/rural
...
20. State Cancer Legislative Database (SCLD)
Information available
For evaluating the effect of state legislation on public health and on the application of cancer control science
For monitoring legislative trends that may reflect changing public attitudes...
21. The National Cancer Institute's Web Site - Cancer.gov
The NCI's gateway Web site, Cancer.gov, provides access to:
Cancer information, including the PDQ database of peer-reviewed information summaries and NCI cancer information publications
Clinical trials information...
22. The Zebrafish Gene Collection (ZGC)
The Zebrafish Gene Collection (ZGC) is an NIH initiative that supports the production of cDNA libraries, clones and sequences to provide a complete set of full-length (open reading frame) sequences and cDNA clones of expressed genes for zebrafish....
23. Visuals Online
Visuals Online contains high resolution images from the collections of the Publication Support Branch and Mass Media Office, components of the Office of Communications, National Cancer Institute. Contents include photographs, medical illustrations...
