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AIDSInfo
U.S. Department of Health and Human Services (HHS) resource providing information on HIV/AIDS clinical trials and federally approved HIV treatment and prevention guidelines.

Acquired Immunodeficiency Syndrome

Mobile, Apps, Widgets

Database, Multilanguage

E-mail, Listserv, GovDelivery, RSS, Web 2.0
AIDSInfo API
Provides access to the AIDSinfo drug database fact sheets in XML format. The API returns information from both the professional and patient versions of the AIDSinfo drug database fact sheets based on input query strings.

Acquired Immunodeficiency Syndrome

API

 

 
AIDSInfo HIV/AIDS Glossary
The AIDSinfo HIV/AIDS Glossary is a powerful tool that provides mobile access to over 850 pertinent HIV/AIDS glossary terms in both English and Spanish.

Acquired Immunodeficiency Syndrome

Downloadable Files (TXT, PDF), Mobile, Apps, Widgets

Reference

 
AIDSInfo Mobile
The latest federally approved HIV/AIDS medical practice guidelines, HIV treatment and prevention clinical trials, and other research information.

Acquired Immunodeficiency Syndrome

Mobile, Apps, Widgets

Database

 
Alternatives to Animal Testing Bibliography (ALTBIB)
Bibliography on alternatives to the use of live vertebrates in biomedical research and testing.

Laboratory Animal Science

Downloadable Files (TXT, PDF), Mobile, Apps, Widgets

Database, Reference

 
American Indian Health
Health and well-being of American Indians.

Public Health

Downloadable Files (TXT, PDF)

 

 
Amino Acid Explorer
Explore characteristics of amino acids by comparing their structural and chemical properties, predicting protein sequence changes caused by mutations, viewing common substitutions, and browsing functions of given residues in conserved domains.

Biochemistry

Utilities, Tools, EXE

 

 
Arctic Health
Health and well-being of our planet's northern-most inhabitants.

Public Health

 

Database, Special Interest

 
Asian American Health
Health and well-being of Asian Americans in the United States.

Public Health

Downloadable Files (TXT, PDF)

Multilanguage, Special Interest

 
ASN.1 Format Summary
An International Standards Organization (ISO) data representation format used to achieve interoperability between platforms.

Technology

Utilities, Tools, EXE

 

 
Assembly Archive
Links the raw sequence information found in the Trace Archive with assembly information found in publicly available sequence repositories (GenBank/EMBL/DDBJ). The Assembly Viewer shows the multiple sequence alignments as well as the actual sequence chromatogram.

Biotechnology

Utilities, Tools, EXE

Database

 
Basic Local Alignment Search Tool (BLAST)
Find regions of local similarity between sequences and compare nucleotide or protein sequences to sequence databases and calculate the statistical significance of matches.

Biochemistry

 

Database

 
Batch Entrez
Retrieve records from Entrez databases by uploading a file of GI or accession numbers from the Nucleotide or Protein databases, or a file of unique identifiers from other Entrez databases. Save results in various formats.

Technology

Utilities, Tools, EXE

 

 
BioAssay Services
Tools that summarize the biological test results in the PubChem database and provide alternative ways to view bioassay results and structure-activity relationships. Users also can download their analyses and data tables.

Chemistry; Epidemiology

Utilities, Tools, EXE

 

 
Bioethics
Ethical, legal, and policy issues in health care and biomedical research.

Ethics

 

Database

 
BioSample
Database containing descriptions of biological source materials used in experimental assays.

Biology

 

Database

 
BioSystems
Database grouping biomedical literature, small molecules, and sequence data in terms of biological relationships.

Biotechnology; Molecular Biology

 

Database

 
Biotechnology Information
Molecular biology, computational biology and related software tools.

Biotechnology; Molecular Biology

FTP

Database

E-mail, Listserv, GovDelivery, RSS
BLAST (Stand-alone)
Suite of BLAST tools that utilize the NCBI C++ Toolkit.

Biochemistry; Molecular Biology

FTP, Utilities, Tools, EXE

Database

 
BLAST API
API for Basic Local Alignment Search Tool (BLAST) services which find regions of local similarity between sequences. The program compares nucleotide or protein sequences to sequence databases and calculates the statistical significance of matches.

Biochemistry; Molecular Biology

API

 

 
BLAST Databases
Sequence databases for use with the stand-alone BLAST programs. The files in this directory are pre-formatted databases that are ready to use with BLAST.

Biochemistry; Molecular Biology

FTP

Database

 
BLAST Link (BLink)
A link option on protein records that displays the results of a pre-computed BLAST search of that protein against all other protein sequences at NCBI.

Biochemistry; Molecular Biology

Utilities, Tools, EXE

 

 
BLAST Microbial Genomes
Performs a BLAST search for similar sequences from selected complete eukaryotic and prokaryotic genomes.

Biochemistry; Molecular Biology

Utilities, Tools, EXE

 

 
BLAST Tutorials and Guides
Links to BLAST-related tutorials and guides, including a selection guide for BLAST algorithms, descriptions of BLAST output formats, explanations of the parameters for stand-alone BLAST, directions for setting up stand-alone BLAST on local machines and using the BLAST URL API.

Biochemistry; Education; Molecular Biology

Utilities, Tools, EXE

Training

E-mail, Listserv, GovDelivery, RSS
Bookshelf
A collection of online biomedical books whose full text can be searched through the Entrez system.

Medicine

 

Database

E-mail, Listserv, GovDelivery, RSS
Cancer Chromosomes
Search for cytogenetic, clinical, and/or reference information.

Genetics, Medical; Molecular Biology; Neoplasms

FTP

Database

 
Cancer Information
Cancer information via the MEDLINE/PubMed database and the National Cancer Institute (NCI).

Neoplasms

 

Database

 
CDTree
A stand-alone application for classifying protein sequences and investigating their evolutionary relationships. CDTree can import, analyze and update existing Conserved Domain (CDD) records and hierarchies, and also allows users to create their own.

Biochemistry

Utilities, Tools, EXE

 

 
Chemical Carcinogenesis Research Information System (CCRIS)
Carcinogenicity, mutagenicity, tumor promotion, and tumor inhibition test results on chemicals.

Neoplasms; Toxicology

 

 

E-mail, Listserv, GovDelivery, RSS
Chemical Hazards Emergency Medical Management (CHEMM)
Enables first responders and other healthcare providers and planners to plan for, respond to, recover from, and mitigate the effects of mass-casualty incidents involving accidental or terrorist chemical releases.

Disaster Medicine; Education; Emergency Medicine; Environmental Health

Downloadable Files (TXT, PDF)

Database, Training

E-mail, Listserv, GovDelivery, RSS
Chemical Identification Plus Database (ChemIDplus)
Online dictionary of chemicals, including names, synonyms, and chemical structures.

Chemistry

 

 

E-mail, Listserv, GovDelivery, RSS
ChemSpell API
The ChemSpell Web Service API provides chemical name spell checking and chemical name synonym look-up.

Chemistry

API

 

 
Citing Medicine
Provides guidance for citing twenty-six types of published and unpublished material, ranging from print books and journal articles to blogs and wikis.

Library Science

 

Reference

 
Clinical Alerts
Messages provided to expedite the release of findings from the NIH-funded clinical trials where such release could significantly affect morbidity and mortality.

Drug Therapy; Therapeutics

 

Database

E-mail, Listserv, GovDelivery, RSS
ClinicalTrials.gov
Patient studies for drugs and treatment.

Drug Therapy; Education; Therapeutics

 

Database, Special Interest, Training

 
ClinicalTrials.gov API
Method for creating links to ClinicalTrials.gov or downloading ClinicalTrials.gov data in XML format. Obtain information including a trial's purpose, who may participate, locations, and phone numbers for more details about clinical trials being conducted throughout the United States and in many countries throughout the world.

Drug Therapy; Therapeutics

API

 

 
CloneDB (formerly Clone Registry)
A database that integrates information about clones and libraries, including sequence data, map positions and distributor information.

Genetics; Molecular Biology

FTP, Utilities, Tools, EXE

Database

 
Cn3D
A stand-alone application for viewing 3-dimensional structures from NCBI Entrez retrieval service. Runs on Windows, Macintosh, and UNIX and can be configured to receive data from most popular Web browsers.

Biochemistry; Education

Utilities, Tools, EXE

Training

 
COBALT
COBALT is a protein multiple sequence alignment tool that finds a collection of pairwise constraints derived from conserved domain database, protein motif database, and sequence similarity, using RPS-BLAST, BLASTP, and PHI-BLAST.

Biochemistry

Utilities, Tools, EXE

 

 
Coffee Break
A collection of short stories and interactive tutorials about recent biomedical discoveries.

Education; Medicine

 

Database, Training

 
Comparative Toxicogenomics Database (CTD)
Contains manually curated data describing cross-species chemical-gene/protein interactions and chemical-and gene-disease relationships.

Environmental Health; Genetics; Toxicology

 

Database

 
Computational Resources from NCBI Structure Group
A centralized resource covering databases and tools to help in the study of macromolecular structures, conserved domains and protein classification, small molecules and their biological activity, biological pathways, and systems.

Biochemistry

Utilities, Tools, EXE

Database

 
Concise Microbial Protein BLAST
A specialized BLAST service in which the queried database consists of all proteins from complete microbial (prokaryotic) genomes. NCBI has precalculated clusters of similar proteins at the genus-level and one representative is chosen from each cluster in order to reduce the dataset, thereby reducing search time and providing a broader taxonomic view.

Biochemistry; Molecular Biology

Utilities, Tools, EXE

 

 
Consensus CDS (CCDS)
A collaborative effort to identify a core set of human and mouse protein coding regions that are consistently annotated and of high quality.

Genetics

FTP

Database

 
Conserved Domains Database (CDD)
Collection of sequence alignments and profiles representing protein domains conserved in molecular evolution.

Biochemistry; Molecular Biology

FTP

Database

 
DailyMed
Vehicle for access to the labels as well as to other sources and types of information about medications.

Drug Therapy; Pharmacology

Downloadable Files (TXT, PDF)

Database, Images

E-mail, Listserv, GovDelivery, RSS
DailyMed API
Provides high quality information about marketed drugs, including FDA labels (package inserts). Currently DailyMed publishes “RESTful” API for querying DailyMed database.

Drug Therapy; Pharmacology

API

 

 
DailyMed Mobile
Provides high quality information about marketed drugs, including FDA labels (package inserts).

Drug Therapy

Mobile, Apps, Widgets

Database

 
Database of Expressed Sequence Tags (dbEST)
A division of GenBank that contains short single-pass reads of cDNA (transcript) sequences. dbEST can be searched directly through the Nucleotide EST Database.

Biochemistry

 

Database

 
Database of Genome Survey Sequences (dbGSS)
A division of GenBank that contains short single-pass reads of genomic DNA. Can be searched directly through the Nucleotide GSS Database.

Biochemistry; Genetics

 

Database

 
Database of Genomic Structural Variation (dbVar)
The dbVar database has been developed to archive information associated with large scale genomic variation, including large insertions, deletions, translocations and inversions. In addition to archiving variation discovery, dbVar also stores associations of defined variants with phenotype information.

Biochemistry; Genetics

 

Database

 
Database of Genotype and Phenotype (dbGaP)
Data from genome wide association (GWA) studies, which aim to establish associations between genotype and phenotype information to elucidate the link between genes and disease.

Genetics, Medical; Molecular Biology

FTP, Submission Systems

Database

E-mail, Listserv, GovDelivery, RSS
Database of Major Histocompatibility Complex (dbMHC)
An open, publicly accessible platform where the Human Leukocyte Antigen system (HLA) community can submit, edit, view, and exchange data related to the human Major Histocompatibility Complex.

Biochemistry

FTP, Submission Systems

Database

 
Database of Single Nucleotide Polymorphisms (dbSNP)
Includes single nucleotide polymorphisms, microsatellites, and small-scale insertions and deletions. Contains population-specific frequency and genotype data, experimental conditions, molecular context, and mapping information for both neutral polymorphisms and clinical mutations.

Molecular Biology

 

Database

 
Developmental and Reproductive Toxicology Database (DART)
References to the teratology, developmental, and reproductive toxicology literature.

Reproductive Medicine; Toxicology

 

Database

 
Dietary Supplements Labels Database
Information about ingredients in more than two thousand selected brands of dietary supplements.

Nutritional Sciences

 

Database

 
Digital Collections
Online archive of biomedical resources including books and films.

History of Medicine; Medicine

Downloadable Files (TXT, PDF), HTML, XML, MARC

Database, Images

Multimedia
Digital Differential Display
A tool for comparing EST profiles in order to identify genes with significantly different expression levels.

Genetics

Utilities, Tools, EXE

Database

 
Directory of History of Medicine Collections
Research, reference and interlibrary loan services.

History of Medicine

 

Database

 
DIRLINE
Online Directory of Health Organizations.

Health Services

Mobile, Apps, Widgets

Database

 
DIRLINE API
Offers a RESTful Web Service API that allows users to search the DIRLINE database with keywords. This service returns search results with brief records and full records in DIRLINE API Response Format.

Health Services

API

 

 
Disaster Information
Health information resource and informatics research related to disasters of natural, accidental, or deliberate origin.

Disaster Medicine

 

 

E-mail, Listserv, GovDelivery, RSS, Web 2.0
Distance Education Program Resources
Distance education resource for many NLM products.

Education

 

Training

 
DOCLINE
Interlibrary loan (ILL) request, routing, and referral system.

Library Science

Downloadable Files (TXT, PDF)

Images

 
Drug Information
Information about U.S. drugs.

Drug Therapy; Pharmacology

 

Special Interest

 
Drug Information Portal
Gateway to current, accurate drug information from NLM and other key government agencies.

Drug Therapy; Pharmacology

 

Database

 
E-Bench
Interactive tool that allows users to build E-utility URLs, view the raw output, and test in a simple environment before including in applications.

Technology

Utilities, Tools, EXE

 

 
Ebot
A tool that allows users to construct an E-utility analysis pipeline using an online form, and then generates a Perl script to execute the pipeline.

Technology

Utilities, Tools, EXE

 

 
Electronic PCR (e-PCR)
A computational procedure used to identify sequence tagged sites (STSs) within DNA sequences.

Biochemistry

Utilities, Tools, EXE

 

 
Embryo
Visually explore human embryo development with the Carnegie Embryo Collection mobile device.

Anatomy; Embryonic Development; Neuroanatomy

Mobile, Apps, Widgets

 

 
Entrez
Search the biomedical databases of the Entrez Molecular Biology System.

Medicine; Molecular Biology

 

Database

 
Entrez Programming Utilities
Tools that provide access to data within the NCBI Entrez system outside of the regular Web query interface. They provide a method of automating Entrez tasks within software applications. Each utility performs a specialized retrieval task, and can be used simply by writing a specially formatted URL.

Technology

API

 

 
Environmental Health and Toxicology Information
Portal to numerous NLM databases and resource in environmental health and toxicology.

Environmental Health; Toxicology

 

Database

E-mail, Listserv, GovDelivery, RSS
Epigenomics
This resource provides a unique interface to search and navigate epigenomic data in the context of biological sample information, as well as tools to select, download and view multiple sets of epigenomic data as tracks on genome browsers.

Genetics; Molecular Biology

 

Database

 
FASTA BLAST Databases
Sequence databases in FASTA format for use with the stand-alone BLAST programs. These databases must be formatted using formatdb before they can be used with BLAST.

Biochemistry

FTP

 

 
Frequency-weighted Link (FLink)
FLink is a tool that enables you to link from a group of records in a source database to a ranked list of associated records in a destination database based on frequency-weighted statistics.

Technology

Utilities, Tools, EXE

 

 
GenBank
Genetic sequence database.

Genetics; Molecular Biology

FTP

Database

 
GenBank: BankIt
A Web-based sequence submission tool for one or a few submissions to the GenBank database, designed to make the submission process quick and easy.

Genetics; Molecular Biology

Submission Systems

 

 
GenBank: Barcode
Tool for submission to the GenBank database of Barcode short nucleotide sequences from a standard genetic locus for use in species identification.

Genetics; Molecular Biology

Submission Systems

 

 
GenBank: Sequin
A stand-alone software tool developed by the NCBI for submitting and updating entries to public sequence databases (GenBank, EMBL, or DDBJ). For simple submission, use the online submission tool BankIt instead.

Genetics; Molecular Biology

Submission Systems

 

 
GenBank: tbl2asn
A command-line program that automates the creation of sequence records for submission to GenBank using many of the same functions as Sequin. It is used primarily for submission of complete genomes and large batches of sequences.

Genetics; Molecular Biology

Submission Systems

 

 
Gene
Database of gene-specific information. Each record represents a single gene from a given organism and can include, as available, nomenclature, map, sequence, expression, structure, functional, and homology data.

Genetics; Molecular Biology

FTP

Database

 
Gene Expression Nervous System Atlas (GENSAT)
Maps the expression of all genes expressed in the mouse brain at various stages of development.

Genetics; Molecular Biology; Neurology

FTP

Database

 
Gene Expression Omnibus (GEO) BLAST
Tool for aligning a query sequence (nucleotide or protein) to GenBank sequences included on microarray or SAGE platforms in the GEO database.

Genetics; Molecular Biology

Utilities, Tools, EXE

 

 
Gene Expression Omnibus (GEO) Database
A public functional genomics data repository supporting MIAME-compliant data submissions. Array- and sequence-based data are accepted and tools are provided to help users query and download experiments and curated gene expression profiles.

Genetics; Molecular Biology

 

Database

 
Gene Expression Omnibus (GEO) Datasets
A component of the Gene Expression Omnibus (GEO) repository that contains submitter-supplied records (known as "GEO Series"), which summarize individual experiments, plus GEO DataSets that are assembled by GEO staff.

Genetics; Molecular Biology

FTP, Utilities, Tools, EXE

Database

 
Gene Expression Omnibus (GEO) Profiles
Individual gene expression and molecular abundance profiles assembled from the Gene Expression Omnibus (GEO) repository. A Profile consists of the expression measurements for an individual gene across all Samples in a DataSet.

Genetics; Molecular Biology

FTP, Utilities, Tools, EXE

Database

 
Gene Expression Omnibus (GEO) Web Deposit
Submit expression data, such as microarray, SAGE or mass spectrometry datasets to the NCBI Gene Expression Omnibus (GEO) database.

Genetics; Molecular Biology

Submission Systems

 

 
Gene Plot
A tool for pairwise comparison of two prokaryotic genomes that displays pairs of protein homologs that are symmetrical best hits between the two genomes.

Genetics; Molecular Biology

Utilities, Tools, EXE

 

 
GENE-TOX (Genetic Toxicology DataBank)
Mutagenicity test data on chemicals based on peer review of the scientific literature.

Genetics; Toxicology

 

Database

 
GeneED
Explore topics such as Cell Biology, DNA, Genes, Chromosomes, Heredity/Inheritance Patterns, Epigenetics/Inheritance and the Environment, Genetic Conditions, Evolution, Biostatistics, Biotechnology, DNA Forensics, and Top Issues in Genetics.

Biotechnology; Education; Genetics

Downloadable Files (TXT, PDF)

Training

E-mail, Listserv, GovDelivery, RSS, Multimedia, Web 2.0
GeneRIF
GeneRIF provides a simple mechanism to allow scientists to add to the functional annotation of genes in the Gene database.

Genetics; Molecular Biology

Submission Systems

 

 
Genes and Disease
Summary information for more than 80 genetic disorders with discussions of the underlying mutation(s) and clinical features, as well as links to related databases and organizations.

Genetics; Molecular Biology

 

Database

 
GeneTests
A publicly funded medical genetics information resource developed for physicians, other healthcare providers, and researchers, available at no cost to all interested persons.

Genetics; Molecular Biology

 

Database

 
Genetic Codes
Displays the genetic codes for organisms in the Taxonomy database in tables and on a taxonomic tree.

Genetics; Molecular Biology

Utilities, Tools, EXE

 

 
Genetics Home Reference
Genetic conditions and the genes or chromosomes responsible.

Genetics, Medical; Molecular Biology

 

Reference

 
Genetics Home Reference API
Method for creating links or downloading Genetics Home Reference data in XML format. This service contains consumer information about genetic conditions, genes, and chromosome related to those conditions.

Genetics, Medical; Molecular Biology

API

 

 
Genome
Sequence and map data from the whole genomes of organisms. The genomes represent both completely sequenced organisms and those for which sequencing is in progress.

Genetics; Molecular Biology

FTP

Database

 
Genome Mapping Data
Contains directories for each genome that include available mapping data for current and previous builds of that genome.

Genetics; Molecular Biology

FTP

 

 
Genome Project
Searchable collection of complete and incomplete (in-progress) large-scale sequencing, assembly, annotation, and mapping projects for cellular organisms. The Entrez Genome Project database provides an umbrella view of the status of each genome project, links to project data in the other Entrez databases, and links to a variety of other NCBI and external resource associated with a given genome project.

Genetics; Molecular Biology

Submission Systems

Database

E-mail, Listserv, GovDelivery, RSS
Genome ProtMap
Maps each protein from a COG or VOG back to its genome, and displays all the genomic segments coding for members of this particular group of related proteins. The view can be shifted to focus on an adjacent COG/VOG, and clusters can be searched by name, protein gig, or gene locus tag.

Genetics; Molecular Biology

Utilities, Tools, EXE

 

 
Genome Reference Consortium (GRC)
Maintains responsibility for the human and mouse reference genomes and works to correct misrepresented loci and to close remaining assembly gaps. In addition, the GRC seeks to provide alternate assemblies for complex or structurally variant genomic loci.

Genetics; Molecular Biology

 

Database

 
Genome Remapping Service
NCBI Remap tool allows users to project annotation data from one assembly to another through a base by base analysis. Options are provided to adjust the stringency of remapping, and summary results are displayed on the page.

Genetics; Molecular Biology

Utilities, Tools, EXE

 

 
Genome UniSTS
A comprehensive database of sequence tagged sites (STSs) derived from STS-based maps and other experiments. STSs are defined by PCR primer pairs and are associated with additional information, such as genomic position, genes, and sequences.

Genetics; Molecular Biology

FTP

Database

 
Genome Workbench
An integrated application for viewing and analyzing sequence data. With Genome Workbench, you can view data in publically available sequence databases at NCBI, and mix these data with your own data.

Genetics; Molecular Biology

Utilities, Tools, EXE

 

 
Genomic Basic Local Alignment Search Tool (BLAST)
This tool compares nucleotide or protein sequences to genomic sequence databases and calculates the statistical significance of matches.

Genetics; Molecular Biology

Utilities, Tools, EXE

 

 
GenPept
The protein sequences corresponding to the translations of coding sequences (CDS) in GenBank are collected for each GenBank release..Please see the README file in the directory for more information.

Genetics; Molecular Biology; Neurology

FTP

 

 
Haz-Map
Links jobs and hazardous tasks with occupational diseases and their symptoms.

Environmental Health; Toxicology

Mobile, Apps, Widgets

Database

 
Hazardous Substances Data Bank (HSDB)
Comprehensive, peer-reviewed toxicology data for about 5,000 chemicals.

Environmental Health; Occupational Medicine; Toxicology

 

Database

 
Health Data Standards and Privacy
NLM participation in activities relating to nationwide implementation of an interoperable health information technology infrastructure to improve the quality and efficiency of health care.

Health Services; Jurisprudence

Downloadable Files (TXT, PDF)

 

 
Health Hotlines
Toll-free telephone numbers for various health-related services.

Health Services

 

Database, Multilanguage

 
Health Hotlines Mobile
Mobile access to the directory of organizations with toll-free telephone numbers.

Health Services

Mobile, Apps, Widgets

Database, Multilanguage

 
Health Services and Sciences Research Resources (HSRR)
Research datasets and instruments/indices.

Health Services Research

 

Database

 
Health Services Research & Health Care Technology
Resources relating to access, cost, and quality issues in healthcare.

Education; Health Services Research

 

Database, Training

 
Health Services Research Information Central    
A health services research information portal.

Health Services Research

 

Reference

Web 2.0
Health Services Research Projects (HSRProj)
Ongoing grants and contracts in health services research.

Health Services Research

 

Database

 
Health Services Technology Assessment Texts (HSTAT)
Full-text documents providing health information and supporting health care decision making.

Health Services Research

 

Database

 
Healthy People 2020 Structured Evidence Queries
One-click PubMed search strategies related to Healthy People 2020 public health objectives.

Health Services Research

 

Reference, Special Interest

 
History of Medicine
Exhibitions, historical scholarship, and images in medicine.

History of Medicine

 

Images, Reference

Multimedia
HIV-1, Human Protein Interaction Database
Information about known interactions of HIV-1 proteins with proteins from human hosts. It provides annotated bibliographies of published reports of protein interactions, with links to the corresponding PubMed records and sequence data.

Acquired Immunodeficiency Syndrome

 

Database

 
HIV/AIDS Resources
Information on Acquired Immunodeficiency Syndrome (AIDS) and Human Immunodeficiency Virus (HIV).

Acquired Immunodeficiency Syndrome

 

Reference

 
HomoloGene
System for automated detection of homologs among the annotated genes of several completely sequenced eukaryotic genomes.

Genetics; Molecular Biology

FTP

 

 
Household Products Database
Health and safety information on household products.

Environmental Health; Toxicology

 

Database

 
Images from the History of Medicine
Nearly 70,000 Images in the prints and photograph collection of the History of Medicine Division (HMD).

History of Medicine

Downloadable Files (TXT, PDF)

Database, Images

Multimedia
Index Catalogue
National Library of Medicine digital version of the printed Index-Catalogue of the Library of the Surgeon General's Office (IndexCat).

Library Science

 

Database

 
Influenza Virus Resource
Provides researchers with a growing collection of virus sequences essential to the identification of the genetic determinants of influenza pathogenicity.

Molecular Biology; Virology

FTP

Database

 
Integrated Risk Information System (IRIS)
Hazard identification and dose-response assessments on chemicals.

Environmental Health; Toxicology

 

Database

 
Interlibrary Loan
Interlibrary loan services are available only to libraries.

Library Science

 

Reference

 
International Toxicity Estimates for Risk (ITER)
Risk information on chemicals from several authoritative organizations worldwide.

Environmental Health; Toxicology

 

Database

 
Journals in NCBI Databases
Look up journals cited in NCBI databases, including PubMed.

Library Science

FTP

Database

 
LactMed - Drugs and Lactation Database
A peer-reviewed and fully referenced database of drugs to which breastfeeding mothers may be exposed.

Obstetrics; Toxicology

 

Database

 
LactMed App for iPhone/iPod Touch
Find information about maternal and infant drug levels, possible effects on lactation and on breastfed infants, and alternative drugs to consider.

Obstetrics; Toxicology

Mobile, Apps, Widgets

Database

 
LinkOut
Third parties can link directly from PubMed and other Entrez database records to relevant Web-accessible resources beyond the Entrez system. Resources include full-text publications, biological databases, consumer health information and research tools.

Library Science

Utilities, Tools, EXE

 

 
List of Serials Indexed for Online Users
Bibliographic information for serials indexed in MEDLINE (available in both PDF and XML).

Library Science

Downloadable Files (TXT, PDF), FTP, HTML, XML, MARC

 

 
Loansome Doc
Enables PubMed and NLM Gateway users to order documents found in MEDLINE.

Library Science

Downloadable Files (TXT, PDF)

 

 
LocatorPlus
Catalog of books, journals, and audiovisuals with holdings, availability, MARC 21, and more.

Library Science

 

Database

 
Malaria Research Resources
Supports African scientists and malaria researchers.

Tropical Medicine

 

Special Interest

 
Map Viewer
A software component of the Genome database that provides special browsing capabilities for a subset of organisms. You can view and search an organism's complete genome, display chromosome maps, and zoom into progressively greater levels of detail, down to the sequence data for a region of interest.

Genetics

Utilities, Tools, EXE

 

 
Medical Subject Headings (MeSH)
Controlled vocabulary thesaurus and MeSH Browser.

Medical Informatics

Downloadable Files (TXT, PDF), HTML, XML, MARC

Database

 
MEDLINE Leasing
NLM leases MEDLINE/PubMed to U.S. individuals or organizations.

Library Science

FTP

Reference

 
MEDLINE/PubMed
References including abstracts to articles in thousands of biomedical journals.

Medicine

 

Database

 
MEDLINE/PubMed Baseline Repository (MBR)
Resources related to the annual baseline files. Includes a query tool for Web-based searching for use by NLM registered MEDLINE/PubMed licensees.

Library Science

Downloadable Files (TXT, PDF)

Database

 
MedlinePlus
Health information for patients, families and health care providers. Also in Spanish.

Medicine

 

Database, Multilanguage

Web 2.0
MedlinePlus Connect
A free service that allows electronic health record (EHR) systems to link to relevant and authoritative health information from MedlinePlus.

Library Science; Medicine

Utilities, Tools, EXE

 

 
MedlinePlus Connect API
Available as a Web application that responds to requests with an on-demand, formatted MedlinePlus Connect Web page or a Web service in which a patient portal or EHR may select which MedlinePlus links and information to provide from within the system instead of automatically providing a link to the standard MedlinePlus Connect response page.

Library Science; Medicine

API

 

 
MedlinePlus en español
Health information for patients, families and health care providers in Spanish.

Medicine

Mobile, Apps, Widgets

Database, Multilanguage

 
MedlinePlus Health Topics API
Provides access to health topic data in XML format. The service accepts keyword searches as requests and returns links to relevant English-language health topics in ranked order.

Medicine

API

 

 
MedlinePlus Mobile
Authoritative consumer health information from MedlinePlus.gov in a mobile-optimized Web site

Medicine

Mobile, Apps, Widgets

Database

 
MeSH Browser
Medical Subject Heading search tool.

Library Science; Medical Informatics

 

Database

 
MeSH Database
NLM controlled vocabulary used for indexing articles for MEDLINE/PubMed. MeSH terminology provides a consistent way to retrieve information that may use different wording for the same concepts.

Medical Informatics

 

Database

 
MetaMap
Highly configurable program to map biomedical text to the UMLS Metathesaurus or, equivalently, to discover Metathesaurus concepts referred to in text. MetaMap uses a knowledge intensive approach based on symbolic, natural language processing (NLP) and computational linguistic techniques.

Medical Informatics

Datasets, XLS, CSV

 

 
MetaMap API
The MetaMap Java API and the MetaMap UIMA Annotator allow users to access MetaMap directly through their Java-based application(s).

Medical Informatics

API

 

 
Mobile Resources
NLM projects involving Web sites and resources designed for mobile devices.

Library Science

Mobile, Apps, Widgets

 

 
Molecular Biology
Molecular biology, computational biology and related software tools.

Molecular Biology

FTP

 

E-mail, Listserv, GovDelivery, RSS
MyMedicationList
Manage medication lists and make the records readily available when needed.

Medicine; Pharmacy

Utilities, Tools, EXE

 

 
National Drug File - Reference Terminology API
Provides clinical information about medications, including therapeutic intent, mechanism of action, physiologic effect and drug-drug interactions. Two NDF-RT APIs (SOAP/WSDL and RESTful) available to provide developers with functions for retrieving NDF-RT data from the most current NDF-RT data set.

Pharmacy

API

 

 
National Library of Medicine DTDs
A Suite of tag sets for authoring and archiving journal articles. Provides a set of XML schema modules that define elements and attributes for describing the textual and graphical content of journal articles as well as some non-article material such as letters, editorials, and book and product reviews.

Library Science

FTP

 

 
NCBI C++ Toolkit Manual
A comprehensive manual on the NCBI C++ toolkit, including its design and development framework, a C++ library reference, software examples and demos, FAQs and release notes. The manual is searchable online and can be downloaded as a series of PDF documents.

Biotechnology

 

Database

 
NCBI Data Specifications
Specifications for NCBI data in ASN.1 or DTD format. The “NCBI_data_conversion.html” links to the conversion tool.

Library Science

FTP

 

 
NCBI Education Page
Links to tutorials and training materials, including PowerPoint slides and print handouts.

Biotechnology; Education

 

Database, Training

 
NCBI Field Guide Manual
Downloadable material for previously offered NCBI Field Guide training course.

Biotechnology; Education

FTP

Training

 
NCBI Glossary
Part of the NCBI Handbook, this glossary contains descriptions of NCBI tools and acronyms, bioinformatics terms and data representation formats.

Biotechnology

 

Database

 
NCBI Handbook
An extensive collection of articles about NCBI databases and software.

Biotechnology

 

Database

 
NCBI Help Manual
Accessed through the NCBI Bookshelf, the Help Manual contains documentation for many NCBI resources, including PubMed, PubMed Central, the Entrez system, Gene, SNP and LinkOut. All chapters can be downloaded in PDF format.

Biotechnology

 

Database

 
NCBI News
Monthly newsletter provides information on new and updated databases, and software services. Articles highlight and demonstrate services, features, tools, and interesting data with practical examples of their use.

Biotechnology

Utilities, Tools, EXE

 

 
NCBI Structure Course Materials
PowerPoint slides, handouts and exercises for the previously offered NCBI course "Exploring 3D Molecular Structures".

Biotechnology; Education

FTP

Training

 
NCBI Toolbox
A set of software and data exchange specifications used by NCBI to produce portable, modular software for molecular biology. Primarily designed to read records in Abstract Syntax Notation 1 (ASN.1) format, an International Standards Organization (ISO) data representation format.

Biotechnology

Utilities, Tools, EXE

 

 
NCBI Website Search
A database of static NCBI Web pages, documentation, and online tools.Including specialized online sequence analysis tools, back issues of newsletters, legacy resource description pages, sample code, and other miscellaneous resources. Equivalent to a site search tool for the whole NCBI web site excluding FTP site.

Biotechnology

 

Database

 
NIH Manuscript Submission System (NIHMS)
The NIH Public Access Policy requests that researchers funded by NIH submit their final, peer-reviewed manuscripts, which have been accepted for publication, to PubMed Central.

Library Science

Submission Systems

 

 
NIH Public Access
The NIH Public Access Policy ensures that the public has access to the published results of NIH-funded research. The NIH Manuscript Submission System is a mechanism for authors to deposit their NIH-funded manuscripts.

Library Science

 

Database, Reference

 
NIHSeniorHealth
Easily-accessible age-related health information.

Geriatrics

Utilities, Tools, EXE

 

 
NLM Catalog
An alternate way to search books, journals, audiovisuals, electronic, and other materials with links to LocatorPlus holdings and availability.

Library Science

 

Database

E-mail, Listserv, GovDelivery, RSS
NLM Classification
Medical library classification and index tool for the arrangement of library materials.

Education; Library Science

Downloadable Files (TXT, PDF), HTML, XML, MARC

Database, Training

 
NLM Gateway
Search multiple retrieval systems.

Library Science; Medicine

 

Database

 
NLM Technical Bulletin
Web-based newsletter for NLM online searchers.

Library Science

Downloadable Files (TXT, PDF)

 

E-mail, Listserv, GovDelivery, RSS
Nucleotide
Contains nucleotide sequence data from organisms. Includes data from a number of sources databases such as GenBank, RefSeq, TPA, and PDB.

Molecular Biology

FTP, Utilities, Tools, EXE

Database

 
OLDMEDLINE Data
References to biomedical journal articles 1947 through 1965.

Medicine

 

Reference

 
OMIA (Online Mendelian Inheritance in Animals)
Database of genes, inherited disorders and traits in animal species (other than human and mouse).

Genetics; Veterinary Medicine

 

Database

 
OMIM (Online Mendelian Inheritance in Man)
Comprehensive, authoritative, and timely compendium of human genes and genetic phenotypes.

Genetics, Medical

FTP

Database

 
Online Exhibitions and Digital Projects
Enhancing the public and scholarly awareness and appreciation of National Library of Medicine collections.

Library Science

 

Database

Multimedia
Open Mass Spectrometry Search Algorithm (OMSSA) Search
Search engine for identifying MS/MS peptide spectra by searching libraries of known protein sequences.

Chemistry

Utilities, Tools, EXE

 

 
Open Reading Frame Finder (ORF Finder)
A graphical analysis tool that finds all open reading frames in a user's sequence or in a sequence already in the database.

Epidemiology; Genetics

Utilities, Tools, EXE

 

 
OSIRIS
A public domain quality assurance software package that facilitates the assessment of multiplex short tandem repeat (STR) DNA profiles based on laboratory-specific protocols.

Molecular Biology

Utilities, Tools, EXE

 

 
Pillbox beta
Pillbox enables rapid identification of unknown solid-dosage medications (tablets/capsules) based on physical characteristics and high-resolution images.

Pharmacy

 

Database

 
Pillbox beta API
Provides access to the pharmaceutical identification and reference system, data, and medication images.

Pharmacy

API

 

 
PopSet
Sets of DNA sequences that have been collected to analyze the evolutionary relatedness of a population.

Epidemiology; Molecular Biology

FTP, Utilities, Tools, EXE

Database

 
Practice Guidelines
Full-text documents providing health information and supporting health care decision making.

Health Services Research

 

Database

 
Primer-BLAST
The Primer-BLAST tool uses Primer3 to design PCR primers to a sequence template. The potential products are then automatically analyzed with a BLAST search against user specified databases, to check the specificity to the target intended.

Biochemistry; Molecular Biology

Utilities, Tools, EXE

 

 
Probe
A public registry of nucleic acid reagents designed for use in a wide variety of biomedical research applications, together with information on reagent distributors, probe effectiveness, and computed sequence similarities.

Chemistry Techniques, Analytical; Molecular Biology

FTP

Database

 
Profiles in Science
Archival collections of leaders in biomedical research and public health.

History of Medicine; Public Health; Science

 

Special Interest

 
ProSplign
A utility for computing alignment of proteins to genomic nucleotide sequence. It is based on a variation of the Needleman Wunsch global alignment algorithm and specifically accounts for introns and splice signals. Due to this algorithm, ProSplign is accurate in determining splice sites and tolerant to sequencing errors.

Biochemistry; Molecular Biology

Utilities, Tools, EXE

 

 
Protein
Contains protein sequences from organisms. Includes data from a number of source databases such as GenPept (translations from annotated coding regions in GenBank), RefSeq, SwissProt, PIR, PRF, and PDB.

Biochemistry; Molecular Biology

FTP, Utilities, Tools, EXE

Database

 
Protein Clusters
A collection of Reference Sequence (RefSeq) proteins, from the complete genomes of prokaryotes, plasmids, and organelles, that have been grouped and annotated based on sequence similarity and protein function.

Biochemistry; Molecular Biology

FTP, Utilities, Tools, EXE

Database

 
PSSM Viewer
Allows users to display, sort, subset and download position-specific score matrices (PSSMs) either from CDD records or from Position Specific Iterated (PSI)-BLAST protein searches. The tool also can align a query protein to the PSSM and highlight positions of high conservation.

Biochemistry; Molecular Biology

Utilities, Tools, EXE

 

 
PubChem
Information on the biological activities of small molecules. PubChem is organized as three linked databases (PubChem Substance, PubChem Compound, PubChem BioAssay) within the Entrez information retrieval system. Links from PubChem's chemical structure records to other Entrez databases provide information on biological properties.

Chemistry

FTP

 

E-mail, Listserv, GovDelivery, RSS, Multimedia
PubChem BioAssay
Contains bioactivity screens of chemical substances described in PubChem Substance. It provides searchable descriptions of each bioassay, including descriptions of the conditions and readouts specific to that screening procedure.

Chemistry Techniques, Analytical

 

Database

 
PubChem Compound
Database made by NCBI and derived from PubChem Substance. A non-redundant view of the chemically validated substances in PubChem Substance. There is one PubChem Compound record for each unique substance, and for each unique substance component. A compound record may link to more than one PubChem Substance record, if different depositors supplied the same structure.

Chemistry

 

Database

 
PubChem Deposition Gateway
This site is for users who want to contribute new data to PubChem and/or test data upload procedures. Contributors first create a test account where they can test the deposition procedures and preview their data records. They may then proceed to a deposition account whereby their data will be uploaded into the public database.

Chemistry

Submission Systems

 

 
PubChem Download Service
This service allows users to download compound or substance records corresponding to a set of PubChem identifiers, which can be supplied manually or through a text file. Numerous download formats are available, including SDF, XML and SMILES.

Chemistry

Downloadable Files (TXT, PDF), HTML, XML, MARC

Images

Multimedia
PubChem Power User Gateway (PUG)
PUG provides access to PubChem services via a programmatic interface. PUG allows users to download data, initiate chemical structure searches, standardize chemical structures and interact with the E-utilities. PUG can be accessed using either standard URLs or via SOAP.

Biotechnology; Chemistry; Technology

API

 

 
PubChem Standardization Service
Standardization, in PubChem terminology, is the processing of chemical structures in the same way used to create PubChem Compound records from contributors' original structures. This service lets users see how PubChem would handle any structure they would like to submit.

Chemistry

HTML, XML, MARC, Utilities, Tools, EXE

 

 
PubChem Structure Search
PubChem Structure Search allows the PubChem Compound Database to be queried by chemical structure or chemical structure pattern. The PubChem Sketcher allows a query to be drawn manually. Users may also specify the structural query input by PubChem Compound Identifier (CID), SMILES, SMARTS, InChI, Molecular Formula, or by upload of a supported structure file format.

Chemistry

Utilities, Tools, EXE

 

 
PubChem Substance
Chemical substance information electronically submitted to PubChem by depositors. This includes any chemical structure information submitted, as well as chemical names, comments, and links to the depositor's Web site.

Chemistry

 

Database

 
Public Health Partners
Information access for the public health workforce.

Public Health

 

 

E-mail, Listserv, GovDelivery, RSS
PubMed
PubMed comprises more than 20 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher web sites

Medicine

 

Database

 
PubMed Central (PMC)
Free digital archive of full text biomedical and life sciences journal literature.

Medicine

Downloadable Files (TXT, PDF), FTP

Images

E-mail, Listserv, GovDelivery, RSS, Multimedia
PubMed Central Open-Access Subset
The PubMed Central (PMC) Open-Access Subset is a relatively small part of the total collection of articles in PMC. Whereas the majority of articles in PMC are subject to traditional copyright restrictions, these articles are protected by copyright, but are made available under a Creative Commons or similar license that generally allows more liberal redistribution and reuse than a traditional copyright. Please refer to the license statement in each article for specific terms of use.

Library Science

FTP

 

 
PubMed Clinical Queries
A specialized PubMed search form targeted to clinicians and health services researchers. The page simplifies searching by clinical study category, finding systematic reviews and searching the medical genetics literature.

Library Science

Utilities, Tools, EXE

 

 
PubMed for Handhelds
Search MEDLINE with the Web browser of any mobile device.

Medicine

Mobile, Apps, Widgets

 

 
PubMed Health
A service that specializes in reviews of clinical effectiveness research (CER), with easy-to-read summaries for consumers as well as full technical reports. CER finds answers to the question “What works?” in medical and health care.

Health Services Research; Medicine

 

Database

 
PubMed Mobile
Provides a simplified mobile friendly Web interface to access PubMed. PubMed comprises more than 20 million citations for biomedical literature from MEDLINE, life science journals, and online books. Citations may include links to full-text content from PubMed Central and publisher Web sites.

Medicine

Mobile, Apps, Widgets

Database

 
PubMed Tutorial
Interactive instruction tool.

Education; Library Science

 

Training

 
Radiation Emergency Medical Management (REMM)
Designed for health care providers, primarily physicians, without formal expertise in radiation safety or radiation medicine who may provide medical care during an accidental or non-accidental radiation event.

Disaster Medicine; Emergency Medicine; Environmental Health

Downloadable Files (TXT, PDF)

Database, Reference

 
Radiation Emergency Medical Management (REMM) Mobile
Guidance for health care providers on the diagnosis and treatment of radiation injuries during radiation and nuclear emergencies.

Disaster Medicine; Emergency Medicine; Environmental Health

Mobile, Apps, Widgets

Database, Reference

 
Reference Sequence (RefSeq)
A collection of curated, non-redundant genomic DNA, transcript (RNA), and protein sequences produced by NCBI. RefSeqs provide a stable reference for genome annotation, gene identification and characterization, mutation and polymorphism analysis, expression studies, and comparative analyses. The RefSeq collection is accessed through the Nucleotide and Protein databases.

Genetics

FTP

Database

 
RefSeqGene
A collection of curated, non-redundant genomic DNA, transcript (RNA), and protein sequences produced by NCBI. RefSeqs provide a stable reference for genome annotation, gene identification and characterization, mutation and polymorphism analysis, expression studies, and comparative analyses. The RefSeq collection is accessed through the Nucleotide and Protein databases.

Genetics

 

Database

 
Refugee Health Information Network
Quality multilingual health information resources for those providing care to resettled refugees and asylees.

Public Health

Downloadable Files (TXT, PDF)

Database, Multilanguage, Special Interest

E-mail, Listserv, GovDelivery, RSS, Multimedia, Web 2.0
Related Structures
The Related Structures tool allows users to find 3D structures from the Molecular Modeling Database (MMDB) that are similar in sequence to a query protein. Although the query protein may not yet have a resolved structure, the 3D shape of a similar protein sequence can shed light on the putative shape and biological function of the query protein.

Biochemistry; Molecular Biology

Utilities, Tools, EXE

 

 
Research Reporting Guidelines and Initiatives: By Organization
A chart of the major biomedical research reporting guidelines that provide advice for reporting research methods and findings.

Jurisprudence; Library Science

 

Reference

 
Resource Guide for Disaster Medicine and Public Health
Guide to freely available online disaster medicine and public health literature and related information.

Disaster Medicine; Public Health

 

Database

E-mail, Listserv, GovDelivery, RSS
Retrovirus Resources
A collection of resources specifically designed to support the research of retroviruses, including a genotyping tool that uses the BLAST algorithm to identify the genotype of a query sequence; an alignment tool for global alignment of multiple sequences; an HIV-1 automatic sequence annotation tool; and annotated maps of numerous retroviruses viewable in GenBank, FASTA, and graphic formats, with links to associated sequence records.

Genetics; Molecular Biology

 

Database

 
ReUnite
A post-disaster family reunification technology. In addition to basic missing person data, it allows image capture, metadata tagging, geo-location, text and voice notes, and support for French and Spanish languages. Available from Apple iTunes.

Disasters; Technology

Mobile, Apps, Widgets

Multilanguage

 
RxNorm
A standardized nomenclature for clinical drugs.

Pharmacy

Datasets, XLS, CSV

 

 
RxNorm API
Provide developers with functions for retrieving RxNorm data from the most current RxNorm data set.

Pharmacy

API

 

 
RxTerms API
RxTerms is a drug interface terminology derived from RxNorm for prescription writing or medication history recording (e.g. in e-prescribing systems, PHRs). There are two RxTerms APIs (SOAP/WSDL and RESTful) available to provide developers with functions for retrieving RxTerms data from the most current RxTerms data set.

Pharmacy

API

 

 
SARS CoV
A summary of data for the SARS coronavirus (CoV), including: links to the most recent sequence data and publications, links to other SARS related resources, and a pre-computed alignment of genome sequences from various isolates.

Genetics; Molecular Biology

 

Database

 
Science Primer
A basic introduction to the science and technology that underlies many of the NCBI resources. A great starting place for students and the general public, the Science Primer provides a basis for understanding the NCBI web site and mission, and provides direct links to many NCBI databases and tools.

Science; Technology

Utilities, Tools, EXE

 

 
Semantic Knowledge Representation (SKR) API
Use UMLS resources in developing effective natural language processing systems that provide semantic interpretation to support innovative information management applications in the biomedical domain. The SKR_API provides access to the entire suite of SKR tools including MetaMap, Medical Text Indexer (MTI), and SemRep, and allows programmatic access to the SKR Batch and Interactive facilities allowing users to submit data and receive results from within their own application(s).

Medical Informatics

API

 

 
Single Nucleotide Polymorphism (dbSNP)
Database of single nucleotide polymorphisms (dbSNP), small-scale insertions/deletions, polymorphic repetitive elements, and microsatellite variation.

Genetics; Molecular Biology

Datasets, XLS, CSV, FTP, Utilities, Tools, EXE

 

 
SKY/M-Fish and CGH Data
SKY-CGH data in ASN.1, XML and EasySKYCGH formats.

Genetics; Molecular Biology

FTP, HTML, XML, MARC

Database

 
SNP Database Specialized Search Tools
Search by genotype, method, population, submitter, markers and sequence similarity.

Biotechnology

Utilities, Tools, EXE

 

 
Social Media
Follow, Fan and Connect with NLM.

Library Science

 

 

E-mail, Listserv, GovDelivery, RSS, Web 2.0
Space Life Sciences Data
Literature of space flight and ground-based life sciences.

Aerospace Medicine

 

Reference

 
Special Queries
Directory of Topic-Specific PubMed Queries, including Clinical Queries.

Medicine; Therapeutics

 

Reference

 
Splign
Compute cDNA-to-Genomic sequence alignments.

Genetics; Molecular Biology

Utilities, Tools, EXE

 

 
Structure (Molecular Modeling Database)
General information about the National Center for Biotechnology Information (NCBI) Structure Group and its research projects, as well as access to the Molecular Modeling Database (MMDB) and related tools to search and display three-dimensional structures.

Biochemistry; Molecular Biology

FTP

Database

 
Structured Abstracts
Information about abstracts with distinct, labeled sections (e.g., Introduction, Methods, Results, discussion) that appear in MEDLINE.

Library Science

Datasets, XLS, CSV, Downloadable Files (TXT, PDF)

 

 
Taxonomy
Contains the names and lineages of organisms, both living and extinct, that are represented in the genetic databases with at least one nucleotide or protein sequence. New organisms are added to the database as sequence data are deposited for them.

Biology; Genetics; Molecular Biology

FTP

 

 
Taxonomy Browser
Search the taxonomy tree using partial taxonomic names, common names, wild cards and phonetically similar names.

Biology; Genetics; Molecular Biology

Utilities, Tools, EXE

 

 
Taxonomy Common Tree
Generates a taxonomic tree for a selected group of organisms. Users can upload a file of taxonomy IDs or names, or they can enter names or IDs directly.

Biology; Genetics; Molecular Biology

Utilities, Tools, EXE

 

 
Taxonomy Statistics
Displays the number of taxonomic nodes in the database for a given rank and date of inclusion.

Biology; Genetics; Molecular Biology

Utilities, Tools, EXE

 

 
Taxonomy Status Reports
Displays the current status of a set of taxonomic nodes or IDs.

Biology

Utilities, Tools, EXE

 

 
TaxPlot
A tool for comparing genomes on the basis of the protein sequences they encode.

Biology

Utilities, Tools, EXE

 

 
Third Party Annotation (TPA) Database
A database that contains sequences built from the existing primary sequence data in GenBank. The sequences and corresponding annotations are experimentally supported and have been published in a peer-reviewed scientific journal. TPA records are retrieved through the Nucleotide Database.

Genetics; Molecular Biology

 

Database

 
Tox Town
Interactive guide to toxic chemicals and environmental health risks. Also in Spanish (ToxTown en español).

Environmental Health; Toxicology

Downloadable Files (TXT, PDF)

Multilanguage

 
Toxicology Data Network (TOXNET)
A cluster of databases covering toxicology, hazardous chemicals, environmental health and related areas.

Environmental Health; Toxicology

 

Database

 
Toxicology Literature Online (TOXLINE)
Over 3 million references to the toxicological literature.

Toxicology

 

Database

 
Toxicology Tutorials
Three college-level tutorials on the basic principles of toxicology, toxicokinetics, and cellular toxicology.

Education; Toxicology

 

Training

 
Toxics Release Inventory (TRI)
Annual estimated releases of toxic chemicals into the environment by industrial facilities in the United States.

Environmental Health; Toxicology

 

Database

 
TOXMAP
Uses maps of the United States to show the amount and location of toxic chemicals released into the environment.

Environmental Health; Toxicology

 

 

E-mail, Listserv, GovDelivery, RSS
ToxMystery
Interactive learning site on toxic substances for children 7-10 years old.

Education; Toxicology

 

Multilanguage, Training

 
TOXNET API
TOXNET API offers a RESTful Web Service API that allows users to search TOXNET databases with keywords.

Environmental Health; Toxicology

API

 

 
Turning the Pages
Digitized images of rare and beautiful historic books in the biomedical sciences.

History of Medicine

Mobile, Apps, Widgets

Multilanguage

 
Turning the Pages Mobile
Explore beautiful historical medical texts with this app for your iPad. Manuscripts come from a variety of regions and eras, from the Islamic medieval world to 19th century Japan to Renaissance Europe.

History of Medicine

Mobile, Apps, Widgets

Multilanguage

 
Unified Medical Language System (UMLS)
Database of biomedical vocabularies (including SNOMED CT), and related semantic and lexical resource for system developers.

Medical Informatics

Datasets, XLS, CSV

Database

E-mail, Listserv, GovDelivery, RSS
Unified Medical Language System (UMLS) Terminology Services API
Intended for application developers to perform Web service calls and retrieve UMLS data within their own applications. Documentation provides a suite of Web Services Description Language (WSDL) files, API installation instructions, and sample code.

Medical Informatics

API

 

 
UniGene
An automated analytical system for producing organized view of the transcriptome from a growing number of organisms. Each UniGene entry is a set of transcript sequences that appear to come from the same transcription locus (gene or expressed pseudogene) in a given organism, together with information on protein similarities, gene expression, cDNA clone reagents, and genomic location.

Genetics; Molecular Biology

FTP

 

 
UniSTS
A unified, non-redundant view of sequence tagged sites (STSs). UniSTS integrates marker and mapping data from a variety of public resource. If two or more markers have different names but the same primer pair, a single STS record is presented for the primer pair and all the marker names are shown.

Genetics; Molecular Biology

FTP

 

 
UniVec
UniVec and UniVec_Core databases in FASTA format.

Technology

FTP

 

 
VecScreen
Quickly identifying segments of a nucleic acid sequence that may be of vector origin.

Molecular Biology

Utilities, Tools, EXE

 

 
Vector Alignment Search Tool (VAST)
A computer algorithm that identifies similar protein 3-dimensional structures. Structure neighbors for every structure in MMDB are pre-computed and accessible via links on the MMDB Structure Summary pages. These neighbors can be used to identify distant homologs that cannot be recognized by sequence comparison alone.

Molecular Biology

Utilities, Tools, EXE

 

 
Viral Genomes
Curated sequence data and related information for the community.

Genetics; Virology

 

Database

 
Viral Genotyping Tool
This tool helps identify the genotype of a viral sequence.

Genetics; Virology

Utilities, Tools, EXE

 

 
Virus Variation
Extension of the Influenza Virus Resource to other organisms, providing an interface to download sequence sets of selected viruses; analysis tools, including virus-specific BLAST pages; and genome annotation pipelines (in progress).

Genetics; Virology

 

Database

 
Visible Human Project
Three-dimensional representations of the human male and female bodies.

Anatomy

Datasets, XLS, CSV, Downloadable Files (TXT, PDF)

Database, Images

 
Voyager
Client/server protocol for fielded search and retrieval of MARC bibliographic records from the NLM integrated library system (ILS). Retrieve in MARC-8 or UTF-8 character encodings.

Library Science

API

 

 
Water Emergency Response for Libraries
Steps on what you should do after a water emergency in your library or cultural heritage institution.

Disasters; Library Science

Mobile, Apps, Widgets

Reference

 
WebWISER
Web-based resource designed to assist first responders in hazardous material incidents.

Education; Emergency Medicine; Environmental Health; Toxicology

Mobile, Apps, Widgets

Training

 
Whole Genome Shotgun Sequences
Whole genome shotgun sequence data organized by the 4-digit project code. Data include GenBank and GenPept flat files, quality scores and summary statistics.

Genetics; Molecular Biology

FTP

 

 
Wireless Information System for Emergency Responders (WISER)
PDA and Web-based resource designed to assist first responders in hazardous material incidents.

Education; Emergency Medicine; Environmental Health; Toxicology

Mobile, Apps, Widgets

Reference, Training

 
Wireless Information System for Emergency Responders (WISER) Mobile
Assist emergency responders in hazardous materials incidents.

Emergency Medicine; Environmental Health; Toxicology

Mobile, Apps, Widgets

 

 
Women's Health Resources
Health topics, research initiatives and overarching themes of the priorities for women's health.

Women's Health

 

Reference, Special Interest

 

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