Selected Publications

This page contains links to scholarly publications about and clinical research, written by staff and others. Titles of journal articles link to the PubMed® abstract for the publication, when available. Links to full-text versions of articles that are freely available are also provided.


Huston M, Williams RJ, Bergeris A, Fun J, Tse T. New Style and New Content for (Full Text). NLM Tech Bull. 2012 Jul-Aug;(387):e5.

Tse T, Zarin DA, Williams RJ, Ide NC. The role and importance of clinical trial registries and results databases. In: Gallin JI, Ognibene FP, eds, Principles and Practice of Clinical Research. 3rd ed. Amsterdam: Academic Press; 2012: 171-81.

Califf RM, Zarin DA, Kramer JM, Sherman RE, Aberle LH, Tasneem A. Characteristics of clinical trials registered in, 2007-2010. JAMA. 2012;307(17):1838-47.

Wong E, Williams R. Requirements and implementation strategies (Full Text, PDF) Regulatory Focus. 2012 May.

Ross JS, Tse T, Zarin DA, Xu H, Zhou L, Krumholz HM. Publication of NIH funded trials registered in cross-sectional analysis. BMJ. 2012;344:d7292. [Full Text]


Zarin DA, Tse T, Williams RJ, Califf RM, Ide NC. The results database—update and key issues. N Engl J Med. 2011;364(9):852-60. [Full Text]

Zarin DA, Tse T. The effect of funding source on outcome reporting among drug trials [letter]. Ann Intern Med. 2011 Jan 18;154(2):137-8.


Williams RJ, Tse T, Harlan WR, Zarin DA. Registration of observational studies: Is it time?. CMAJ. 2010;182(15):1638-42. [Full Text]

Zarin DA, Califf R. Point Counterpoint: Bureaucratic nuisance or opportunity to improve the field? (Full Text, PDF). APOR. 2010;6(2):3-5.


Tse T, Williams RJ, Zarin DA. Reporting "Basic Results" in Chest. 2009;136(1):295-303. [Full Text]

Tse T, Williams RJ, Zarin DA. Update on registration of clinical trials in Chest. 2009;135:304-5. [Full Text]

Tse T, Zarin DA. Clinical trial registration and results reporting: and FDAAA (Full Text, PDF). FDLI Update. 2009;1:18-22.

Zarin DA, Tse T, Williams RJ. Frequency and nature of changes in primary outcome measures. Presented at: Sixth International Congress on Peer Review and Biomedical Publication; September 2009; Vancouver, BC, Canada.

Williams RJ, Tse T, Zarin DA. Characterizing sponsor-imposed restrictions on disclosing results of clinical trials. Presented at: Sixth International Congress on Peer Review and Biomedical Publication; September 2009; Vancouver, BC, Canada. [Poster (PDF)]

Williams RJ, Tse T. A public database of clinical research. Presented at: American Public Health Association 137th Annual Meeting and Expo; November 2009; Philadelphia, PA. [Poster (PDF)]


Tse T, Williams RJ. to include basic results data (Full Text). NLM Tech Bull. 2008 Sep-Oct;(364):e15.

Zarin DA, Tse T. Moving towards transparency of clinical trials. Science. 2008;319(5868):1340-42. [Full Text (author manuscript)]


Drazen JM, Zarin DA. Salvation by registration [editorial]. N Engl J Med. 2007 Jan 11;356(2):184-5. [Full Text]

Zarin DA, Ide NC, Tse T, Harlan WR, West JC, Lindberg DA. Issues in the registration of clinical trials. JAMA. 2007;297(19):2112-20.

Zarin DA, Keselman A. Registering a clinical trial in Chest. 2007;131(3):909-12. [Full Text]

Ide NC, Loane RF, Demner-Fushman D. Essie: A concept-based search engine for structured biomedical text. J Am Med Inform Assoc. 2007;14(3):253-63. [Full Text]

Williams RJ, Tse T. New look for (Full Text). NLM Tech Bull. 2007 Sep-Oct;(358):e2.


Graham L, Tse T, Keselman A. Exploring user navigation during online health information seeking. AMIA Annu Symp Proc. 2006:299-303. [Full Text (PDF)]


Zarin DA, Tse T, Ide NC. Trial registration at between May and October 2005. N Engl J Med. 2005 Dec 29;353(26):2779-87. [Full Text]

Zarin DA, Bergeris A, Ide NC, Tse T.; A report to the Board of Scientific Counselors (Full Text, PDF). Bethesda, Md: Lister Hill National Center for Biomedical Communications, US National Library of Medicine; May 2005. Technical Report LHNCBC-TR-2005-003.

Ripple A, Tse T, Zarin DA. scope expanded (Full Text). NLM Tech Bull. 2005 Jul-Aug;(345):e6.


Gillen JE, Tse T, Ide NC, McCray AT. Design, implementation and management of a web-based data entry system for Stud Health Technol Inform. 2004;107(Pt 2):1466-70. [Full Text (PDF)]


Tse T, Johnson SO, Ripple A. Update: Expanded search capabilities (Full Text). NLM Tech Bull. 2002 Jul-Aug;(327):e5.


McCray AT, Ide NC. Design and implementation of a national clinical trials registry. J Am Med Inform Assoc. 2000 May-Jun;7(3):313-23. [Full Text]
(Note: The article is free, but users must register to access it.)

McCray AT. Better access to information about clinical trials. Ann Intern Med. 2000 Oct 17;133(8):609-14. [Full Text]

McCray AT, Dorfman E, Ripple A, Ide NC, Jha M, Katz DG, Loane RF, Tse T. Usability issues in developing a Web-based consumer health site. Proc AMIA Symp. 2000:556-60. [Full Text (PDF)]

Tse T. Searching (Full Text). NLM Tech Bull. 2000 Sep-Oct;(316):e1.

This page last reviewed in August 2012