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Trends, Charts, and Maps

ClinicalTrials.gov currently lists 140,426 studies with locations in all 50 states and in 182 countries. ClinicalTrials.gov receives more than 95 million page views per month and 60,000 unique visitors daily (as of February 2012).

Contents

• Locations of Registered Studies
• Locations of Recruiting Studies
• Map of Studies Registered on ClinicalTrials.gov
• Types of Registered Studies
• Number of Registered Studies over Time
• Number of Registered Studies with Posted Results over Time

Locations of Registered Studies

This chart shows the distribution of locations for all studies registered on ClinicalTrials.gov.
Total N = 140,426 studies

(Data as of February 12, 2013)

Distribution of locations for all studies registered on ClinicalTrials.gov"

Location	Number of Registered Studies and Percentage of Total
Non-U.S. Only	60,318 (43%)
U.S. Only	57,992 (41%)
Not Specified*	13,122 (9%)
Both U.S. & Non-U.S.	8,994 (6%)
Total	140,426

(Data as of February 12, 2013)

Locations of Recruiting Studies

This chart shows the distribution of locations for recruiting studies registered on ClinicalTrials.gov.
Total N = 29,645 studies

(Data as of February 12, 2013)

Distribution of locations for recruiting studies registered on ClinicalTrials.gov

Location	Number of Recruiting Studies and Percentage of Total
Non-U.S. Only	14,585 (49%)
U.S. Only	13,118 (44%)
Both U.S. & Non-U.S.	1,942 (7%)
Total	29,645

(Data as of February 12, 2013)

Map of Studies Registered on ClinicalTrials.gov

See Studies on a Map for an interactive map of studies that are registered on ClinicalTrials.gov.

Types of Registered Studies

This table shows the number and types of studies that are registered and for which results are available on ClinicalTrials.gov.

(Data as of February 12, 2013)

Study and intervention types with number of registered studies and with number of studies having posted results

Study and Intervention Type		Number of Registered Studies and Percentage of Total	Number of Studies With Posted Results and Percentage of Total***
Total		140,426	8,153
Interventional		113,852 (81%)	7,605 (93%)
Type of Intervention*	Drug or biologic	76,790	6,499
	Behavioral, other	27,669	820
	Surgical procedure	12,812	319
	Device**	9,788	694
Observational		25,933 (18%)	548 (6%)
Expanded Access		196	N/A

* A study may include more than one type of intervention (that is, a single study may be counted more than once). Because of this, the sum of counts by type of intervention do not equal the total number of interventional studies.
** A total of 445 applicable device clinical trials were submitted as "delayed posting" under the Food and Drug Administration Amendments Act of 2007 (FDAAA). That is, the Responsible Party has indicated that such a trial includes a device not previously approved or cleared by the U.S. FDA for any use. These are not included in the count of trials with at least one device.
*** Results are only required to be submitted for certain trials. For example, results submission is generally not required for trials of drugs, biologics, or devices that have not been approved by FDA; observational studies; and trials completed before 2008.

N/A = not applicable

Number of Registered Studies Over Time

The graph below shows the total number of studies registered on ClinicalTrials.gov since 2000, based on the First Received Date. The first version of ClinicalTrials.gov was made available to the public on February 29, 2000.

(Data as of February 12, 2013)

Key

ICMJE: Indicates when the International Committee of Medical Journal Editors began requiring trial registration as a condition of publication under the Uniform Requirements for Manuscripts Submitted to Biomedical Journals (URM) (September 2005).

FDAAA: Indicates when the expanded registration requirements of FDAAA began and were implemented on ClinicalTrials.gov (December 2007).

Years with numbers of registered studies

Year	Total Number of Registered Studies
2000	5,646
2001	6,998
2002	8,596
2003	10,273
2004	12,073
2005	25,033
2006	35,973
2007	49,384
2008	66,432
2009	83,622
2010	101,345
2011	119,494
2012	138,546

(Data as of February 12, 2013)

Number of Registered Studies With Posted Results Over Time

The graph below shows the number of registered studies with results posted on ClinicalTrials.gov, based on the Results First Received Date. ClinicalTrials.gov launched its results database in September 2008, at which time sponsors or investigators were allowed to begin submitting results for their registered studies. The results database was developed to accommodate results submission requirements outlined in FDAAA.

(Data as of February 12, 2013)

Years with numbers of registered studies having posted results

Year	Total Number of Registered Studies With Posted Results
2009	1,798
2010	3,469
2011	5,784
2012	8,119

(Data as of February 12, 2013)