Archive for the ‘Stem Cells’ Category


Stem Cell Workshop Covered Field’s Progress, Challenges and Opportunities

In the decade since NIGMS began supporting human embryonic stem cell (hESC) research, the field has made substantial strides, including the development of methods to generate induced pluripotent stem cells (iPSC). As part of our ongoing commitment to basic research into the fundamental properties of pluripotent cells, we recently hosted our fourth biennial workshop for [...]

Filed under: Meetings/Events, Stem Cells
Permalink: https://loop.nigms.nih.gov/index.php/2011/12/01/stem-cell-workshop-covered-fields-progress-challenges-and-opportunities/

NIGMS Cell Repository Now Includes iPS Cell Lines

As we anticipated last year, the NIGMS Human Genetic Cell Repository (HGCR) now offers human induced pluripotent stem cell lines that carry disease gene mutations. The first five lines to be made available were derived from individuals with Huntington’s disease, juvenile onset diabetes, severe combined immunodeficiency disease, muscular dystrophy and spinal muscular atrophy. The repository [...]

Filed under: Resources, Stem Cells
Permalink: https://loop.nigms.nih.gov/index.php/2011/06/27/nigms-cell-repository-now-includes-ips-cell-lines/

New Funding Opportunity for Stem Cell Researchers

NIGMS has just issued a call for Program Projects for Collaborative Research on the Basic Biology of Pluripotency and Reprogramming (P01), with an emphasis on human induced pluripotent stem (iPS) cells. We are particularly interested in studies that propose comprehensive analyses of the basic biology of pluripotency, the molecular events and mechanisms of reprogramming, and [...]

Filed under: Collaborative Research, Funding Opportunities, Stem Cells
Permalink: https://loop.nigms.nih.gov/index.php/2010/09/24/new-funding-opportunity-for-stem-cell-researchers/

Update: Status of hESC Applications and Grants

NIH has rescinded the earlier notice regarding the status of applications and grants involving human embryonic stem cells. The new notice states that the receipt, processing, review and awarding of NIH applications and proposals involving human embryonic stem cells will continue. It goes on to list the following actions: The suspension of further NIH activity [...]

Filed under: Research Administration, Stem Cells
Permalink: https://loop.nigms.nih.gov/index.php/2010/09/13/update-status-of-hesc-applications-and-grants/

Status of hESC Applications and Grants

NIH has issued a notice describing the status of applications and grants that propose research using human embryonic stem cells (hESC). Among its points are: Any further NIH activity to implement, apply or act pursuant to the NIH Guidelines is hereby suspended until further notice. Issuance of all pending competing, and noncompeting continuation hESC awards [...]

Filed under: Research Administration, Stem Cells
Permalink: https://loop.nigms.nih.gov/index.php/2010/09/03/status-of-hesc-applications-and-grants/

Early Notice: Program Projects for Collaborative Research on the Basic Biology of Pluripotency and Reprogramming

It’s safe to say that the discovery that human non-embryonic cells can be reprogrammed to an embryonic stem cell-like state has created a lot of excitement in the scientific community. These cells provide a wonderful opportunity to investigate the fundamental molecular and genetic properties of pluripotent cells. Last month, the NIGMS Council approved a new [...]

Filed under: Concept Clearances, Stem Cells
Permalink: https://loop.nigms.nih.gov/index.php/2010/06/09/early-notice-program-projects-for-collaborative-research-on-the-basic-biology-of-pluripotency-and-reprogramming/

NIGMS Cell Repository Will Expand Collection, Services

Good news—we just awarded a five-year contract to the Coriell Institute for Medical Research to continue and expand operation of the NIGMS Human Genetic Cell Repository (HGCR) . A lot of NIGMS grantees who do basic research may not be familiar with the HGCR. It currently has more than 10,000 cell lines from individuals who [...]

Filed under: Resources, Stem Cells
Permalink: https://loop.nigms.nih.gov/index.php/2010/01/25/nigms-cell-repository-will-expand-collection-services/

First Human Embryonic Stem Cell Lines Approved Under New Guidelines Now Available

NIH Director Francis Collins announced today that the first 13 human embryonic stem cell (hESC) lines to be approved under the new NIH Guidelines for Human Stem Cell Research have been placed on the NIH Human Embryonic Stem Cell Registry, and NIH grantees may now use them. These lines were not previously eligible for NIH [...]

Filed under: News, Research Administration, Stem Cells
Permalink: https://loop.nigms.nih.gov/index.php/2009/12/02/first-human-embryonic-stem-cell-lines-now-available/

NIGMS Grantees Gather to Report on Stem Cell Research—Progress and Challenges

Human embryonic stem cell research is an area of special interest to NIGMS. It represents a unique opportunity to explore the most fundamental mechanisms of biology and development while providing a foundation for future clinical applications. NIGMS’s support of basic research in embryonic stem cell biology is actually greater than that of any other component [...]

Filed under: Meetings/Events, Stem Cells
Permalink: https://loop.nigms.nih.gov/index.php/2009/10/14/nigms-grantees-gather-to-report-on-stem-cell-research-progress-and-challenges/

Moving Forward with Stem Cell Research

New NIH guidelines for human stem cell research became effective on July 7, 2009. We thank those of you who provided comments on the draft policy. The input NIH received was instrumental in developing the final guidelines, which will generate a new registry of human embryonic stem cells (hESC) eligible for use in NIH-funded projects. [...]

Filed under: News, Stem Cells
Permalink: https://loop.nigms.nih.gov/index.php/2009/07/21/moving-forward-with-stem-cell-research/