High-Performance Computing at the NIH
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The Helix Systems group is responsible for the planning and management of high-performance computing systems specifically for the intramural NIH community. These systems include Helix, a multiprocessor shared-memory system for interactive use; Biowulf, a 12,000+ processor Linux cluster; and Helixweb, which provides a number of scientific tools via the web. We provide access to a wide range of computational applications for molecular and structural biology, mathematical and graphical analysis, and other scientific fields.

Recent Publications Citing Helix and Biowulf:

thumbnail image from paper Genome-wide profiles of CtBP link metabolism with genome stability and epithelial reprogramming in breast cancer
Li-Jun Di, Jung S. Byun, Madeline M. Wong, Clay Wakano, Tara Taylor, Sven Bilke, Songjoon Baek, Kent Hunter, Howard Yang, Maxwell Lee, Cecilia Zvosec, Galina Khramtsova, Fan Cheng, Charles M. Perou, C. Ryan Miller, Rachel Raab, Olufunmilayo I. Olopade & Kevin Gardner
Nature Communications , doi:10.1038/ncomms2438 (2013)

thumbnail image from paper Ischemic stroke is associated with the ABO locus: The EuroCLOT study
FMK Williams, AM Carter, PG Hysi et al and EuroCLOT Investigators, the Wellcome Trust Case Control Consortium 2, MORGAM, MetaStroke and the International Stroke Genetics Consortium
Annals of Neurology , DOI: 10.1002/ana.23838 (2013)

thumbnail image from paper Initial Assessment of the Pathogenic Mechanisms of the Recently Identified Alzheimer Risk Loci
P Holton, M Ryten, MA Nalls et al.
Annals of Human Genetics , DOI: 10.1111/ahg.12000 (2013)

Alternative Complex III from phototrophic bacteria and its electron acceptor auracyanin
Erica L.W. Majumder, Jeremy D. King, Robert E. Blankenship
Biochimica et Biophysica Acta (BBA) - Bioenergetics , doi://10.1016/j.bbabio.2013.01.008 (2013)