NIH and Government Programs and Initiatives in Biomedical Informatics and Computational Biology (BICB)

Maintained by the BISTI consortium. Send comments, suggestions to Peter Lyster.

This is a list of NIH programs and initiatives with a preponderance of or a significant component of biomedical informatics and computational biology (BICB).  A Program is an ongoing effort with prior and possibly future funding opportunity announcements, while an Initiative specifically refers to an active FOA*.  Some P&I appear twice.
*Active FOAs are identified by (A)

Tips on writing a grant in Biomedical Informatics and Computational Biology.

How to Approach NIH for Support for a Computational Project.

For an update on funding of computational grant applications at NIH read the recent editorial in Biocomputational Review.

View a link to the summary of NIH programs in Systems Biology.

Broad-based BISTI initiatives

The Innovations program for regular grant applications (R01) (PAR-09-218) and exploratory high risk/high reward grant applications (R21) (PAR-08-219), and the program contact persons are at http://www.bisti.nih.gov/R01-contacts.cfm. The initiatives use standard receipt dates.  As mentioned above, there should be a preponderance of effort in computing.  Of course it is appropriate to budget some moneys for experimental data acquisition in support of the computational research.  New investigators under these PAs are eligible for shortened review cycle http://grants1.nih.gov/grants/guide/notice-files/NOT-OD-07-083.html.

The Innovations program for SBIR/STTRs are (PAR-09-220) and (PAR-09-221), which use standard receipt dates, and the program contact persons are at http://www.bisti.nih.gov/SBIR-contacts.cfm.  For additional information, the NIH SBIR Funding Opportunities page offers a wealth of information dealing with SBIR/STTR program (not just computing) http://grants.nih.gov/grants/Funding/sbir.htm.

Broad-based or multi Institute Programs and Initiatives

  • Research Project Grant (Parent R01) – PA-11-260, NIH Exploratory Developmental Research Grant Program (R21) – PA-10-069, and the Omnibus Solicitation of the NIH for Small Business Technology Transfer Grant Applications – PA-12-089.  The majority of computational applications go to mainline NIH study sections (BDMA, MABS, BCHI, NT, GCAT, MSFD, BMRD, BMIT, MEDI, and MIS) (A)
  • NEW: Modeling Social Behavior (R01) – RFA-GM-13-006 (A)
  • Interagency Modeling and Analysis Group (IMAG) and IMAG New Funding Opportunities (A)
  • Collaborative Research in Computational Neuroscience (CRCNS): A Joint NSF-NIH initiative: NSF-11-505 (A)
  • Predictive Multiscale Models for Biomedical, Biological, Environmental and Clinical Research (Interagency U01)—PAR-11-203 (A)
  • IMAG Population Modeling Funding Announcements (A)
  • OBSSR Funding Opportunity Announcements in Systems Science (A)
  • Basic Behavioral and Social Sciences Network (OppNet) (A)
  • Social Network Analysis and Health (R01) – PAR-10-145 (A)
  • Systems Science and Health in the Behavioral and Social Sciences (R01) PAR-11-314 (R21) PAR-11-315 (A)
  • Social Network Analysis and Health, One receipt date per year (R01) PAR-10-145 (R21) PAR-10-146 (A)
  • Dissemination and Implementation Research in Health, PAR-10-038 (R01), PAR-10-039 (R03), PAR-10-040 (R21) (A)
  • Mechanisms Underlying the Links between Psychosocial Stress, Aging, the Brain and the Body (R01) -- PA-09-216 (A)
  • The National Center for Research Resources (NCRR) program for Biomedical Technology Research Centers (BTRC).  Some of these have computational focus. The National Institute of Biomedical Imaging and Bioengineering also has a program in Biotechnology Resource Centers. See Announcement for current status.  (A)
  • Climate Change and Health: Assessing and Modeling Population Vulnerability to Climate Change (R21) – PAR-10-235 (A)
  • Transforming Biomedicine at the Interface of the Life and Physical Sciences (R01) – PAR-10-141  (A)
  • New Biomedical Frontiers at the Interface of the Life and Physical Sciences (R01) – PAR-10-142
  • Bioengineering Research Partnerships (R01) – PAR-10-234  (A)
  • Bioengineering Research Grants (R01) – PA-10-009 (A)
  • Exploratory/Developmental Bioengineering Research Grants (EBRG) (R21) – PA-10-010 (A)
  • Notice of Availability of Administrative Supplements for the U.S.-JAPAN Brain Research Cooperative Program – U.S. Component – NOT-NS-10-014 (A)
  • Exceptional, Unconventional Research Enabling Knowledge Acceleration (EUREKA) (R01) – RFA-GM-11-003 RETIRED and replaced by
  • NIH Director’s Transformative Research Awards (R01) – RFA-RM-11-006 (A)
  • Spatial Uncertainty: Data, Modeling, and Communication (R01) – PA-11-238, (R21) – PA-11-239, (R03) – PA-11-240 (A)
  • Lab to Marketplace: Tools for Brain and Behavioral Research (SBIR[R43/44]) – PA-11-134 (A)
  • SHIFT Award: Small Business Helping Investigators to Fuel  the Translation of Scientific Discoveries [SBIR: R43/R44] – PAR-10-122 (A)

Institute Programs or Initiatives

Common Fund and Neuroscience Blueprint Programs or Initiatives

Training Opportunities

  • Short Courses on Mathematical, Statistical, and Computational Tools for Studying Biological Systems (R25) – PA-11-351  (A)
  • Mentored Quantitative Research Development Award (K25) – PA-11-196  (A)
  • Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants (T32) – PA-11-184 (A)
  • NIH Pathway to Independence (PI) Award (K99/R00) – PA-11-197  (A)
  • Ruth L. Kirschstein National Research Service Awards (NRSA) for Individual Postdoctoral Fellows (F32) – PA-11-113  (A)
  • NLM Independent Career Development Award for Biomedical Informatics – (K22)  PAR-10-195

Multi-Agency Programs and Initiatives

Other Agency, Foundation, and International Efforts

If you have any questions about the programs, feel to email: Peter Lyster
Updated 02/08/2012