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Chemical Biology Laboratory

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In addition to the information presented below, the CBL has an alternative website that can provide you with more detail about their work.


The Chemical Biology Laboratory (CBL) is a newly founded (2009) multidisciplinary laboratory that emphasizes chemical science at the interfaces of chemistry, biology and materials science. The CBL conducts basic research central to the discovery of new small molecules, peptides, macromolecules, arrays and materials that impact cancer and AIDS diagnostics and treatment. The CBL evolved from the Laboratory of Medicinal Chemistry (LMC), a lab that had served as the focal point of chemical research within the NCI, historically steeped in the discovery and optimization of anticancer and anti-AIDS drugs. The Chemical Biology Lab was formed to expand the role of chemistry and materials science in defining and manipulating the biological processes that impact cancer and AIDS with the ultimate goal of translating basic research discoveries into therapies.

We are a diverse group of synthetic organic chemists, chemical biologists, materials chemists, analytical chemists, and computational chemists that interact closely to create a collaborative and stimulating research environment. The CBL collaborates extensively with other NCI and broader NIH laboratories as well as academicians to accelerate discovery and translation. The CBL houses state of the art facilities to support chemical biology and materials development including newly constructed organic synthesis laboratories, mass spectrometers, NMR spectrometers, peptide synthesizers, glycan array technologies, rheometer, dynamic mechanical analyzer, CD, UV and FT-IR spectrometers, and a Linux supercomputer cluster.

The CBL is a member of the Molecular Discovery Program along with the Structural Biophysics Laboratory and the Molecular Targets Laboratory.

This page was last updated on 10/13/2011.