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EHP

February 2013 | Volume 121 | Number 2

News

Focus

EHP Cover Image

Phage Renaissance: New Hope against Antibiotic Resistance

Carol Potera | A48-A53

Bacteriophages, or phages for short, are natural viral predators that target bacteria but leave mammalian and plant cells unscathed. Before the widespread use of antibiotics, physicians successfully treated a variety of infections with phages. Today, faced with the growing threat of antibiotic-resistant bacteria, researchers are reinvestigating phages as a potential solution for a variety of medical, agricultural, and environmental problems.

Forum

“Trilongins” Offer Insight into Mold Toxicity

Bob Weinhold | A44

Health Impact Bonds: Will Investors Pay for Intervention?

Rebecca Fairfax Clay | A45

Study Suggests Long-Term Decline in French Sperm Quality

Adrian Burton | A46

The Beat

Erin E. Dooley | A47

Spheres of Influence

Plane flying in sunset

Sunset for Leaded Aviation Gasoline?

Rebecca Kessler | A54-A57

Leaded aviation gasoline (avgas) is one of the few fuels in the United States to still contain lead, and it’s the single largest source of lead emissions in the country. An appropriate replacement fuel has remained surprisingly elusive, but the search for a replacement got a boost in 2012, when a committee of the Federal Aviation Administration issued recommendations and criteria for identifying and approving an unleaded avgas.

 

Science Selections

Lasting Impacts: Pre- and Postnatal PBDE Exposures Linked to IQ Deficits

Kellyn S. Betts | A58

Phthalates and Childhood Asthma: Revealing an Association through Urinary Biomarkers

Tanya Tillett | A59

Road Traffic Noise and Diabetes: Long-Term Exposure May Increase Disease Risk

Wendee Nicole | A60

POPs vs. Fat: Persistent Organic Pollutant Toxicity Targets and Is Modulated by Adipose Tissue

Julia R. Barrett | A61

Commentaries

Data Disclosure for Chemical Evaluations

Randall Lutter, Craig Barrow, Christopher J. Borgert, James W. Conrad Jr., Debra Edwards, and Allan Felsot | 145-148

Assuring Access to Data for Chemical Evaluations

Lynn R. Goldman and Ellen K. Silbergeld | 149-152

Reviews

Persistent Organic Pollutants and Type 2 Diabetes: A Prospective Analysis in the Nurses’ Health Study and Meta-analysis

Hongyu Wu, Kimberly A. Bertrand, Anna L. Choi, Frank B. Hu, Francine Laden, Philippe Grandjean, and Qi Sun | 153-161

Toxicological Function of Adipose Tissue: Focus on Persistent Organic Pollutants

Michele La Merrill, Claude Emond, Min Ji Kim, Jean-Philippe Antignac, Bruno Le Bizec, Karine Clément, Linda S. Birnbaum, and Robert Barouki | 162-169

Evaluation of the Association between Maternal Smoking, Childhood Obesity, and Metabolic Disorders: A National Toxicology Program Workshop Review

Mamta Behl, Deepa Rao, Kjersti Aagaard, Terry L. Davidson, Edward D. Levin, Theodore A. Slotkin, Supriya Srinivasan, David Wallinga, Morris F. White, Vickie R. Walker, Kristina A. Thayer, and Alison C. Holloway | 170-180

Research

Thyroid Hormones in Relation to Lead, Mercury, and Cadmium Exposure in the National Health and Nutrition Examination Survey, 2007–2008

Aimin Chen, Stephani S. Kim, Ethan Chung, and Kim N. Dietrich | 181-186

Associations between Urinary Excretion of Cadmium and Proteins in a Nonsmoking Population: Renal Toxicity or Normal Physiology?

Magnus Akerstrom, Gerd Sallsten, Thomas Lundh, and Lars Barregard | 187-191

Long-term Exposure to PM2.5 and Incidence of Acute Myocardial Infarction

Jaime Madrigano, Itai Kloog, Robert Goldberg, Brent A. Coull, Murray A. Mittleman, and Joel Schwartz | 192-196

Neighborhood Effects on Heat Deaths: Social and Environmental Predictors of Vulnerability in Maricopa County, Arizona

Sharon L. Harlan, Juan H. Declet-Barreto, William L. Stefanov, and Diana B. Petitti | 197-204

Black–White Blood Pressure Disparities: Depressive Symptoms and Differential Vulnerability to Blood Lead

Margaret T. Hicken, Gilbert C. Gee, Cathleen Connell, Rachel C. Snow, Jeffrey Morenoff, and Howard Hu | 205-209

Short-Term Effects of the 2008 Cold Spell on Mortality in Three Subtropical Cities in Guangdong Province, China

Huiyan Xie, Zhibin Yao, Yonghui Zhang, Yanjun Xu, Xiaojun Xu, Tao Liu, Hualiang Lin, Xiangqian Lao, Shannon Rutherford, Cordia Chu, Cunrui Huang, Scott Baum, and Wenjun Ma | 210-216

Long-Term Exposure to Road Traffic Noise and Incident Diabetes: A Cohort Study

Mette Sørensen, Zorana J. Andersen, Rikke B. Nordsborg, Thomas Becker, Anne Tjønneland, Kim Overvad, and Ole Raaschou-Nielsen | 217-222

Association between Long-Term Exposure to Traffic-Related Air Pollution and Subclinical Atherosclerosis: The REGICOR Study

Marcela Rivera, Xavier Basagaña, Inmaculada Aguilera, Maria Foraster, David Agis, Eric de Groot, Laura Perez, Michelle A. Mendez, Laura Bouso, Jaume Targa, Rafael Ramos, Joan Sala, Jaume Marrugat, Roberto Elosua,> and Nino Künzli | 223-230

Persistent Environmental Pollutants and Couple Fecundity: The LIFE Study

Germaine M. Buck Louis, Rajeshwari Sundaram, Enrique F. Schisterman, Anne M. Sweeney, Courtney D. Lynch, Robert E. Gore-Langton, José Maisog, Sungduk Kim, Zhen Chen, and Dana B. Barr | 231-236

Association between Arsenic Suppression of Adipogenesis and Induction of CHOP10 via the Endoplasmic Reticulum Stress Response

Yongyong Hou, Peng Xue, Courtney G. Woods, Xia Wang, Jingqi Fu, Kathy Yarborough, Weidong Qu, Qiang Zhang, Melvin E. Andersen, and Jingbo Pi | 237-243

In Utero Exposure to Arsenic Alters Lung Development and Genes Related to Immune and Mucociliary Function in Mice

Kathryn A. Ramsey, Anthony Bosco, Katherine L. McKenna, Kim W. Carter, John G. Elliot, Luke J. Berry, Peter D. Sly, Alexander N. Larcombe, and Graeme R. Zosky | 244-250

Children’s Health

Urinary Biomarkers for Phthalates Associated with Asthma in Norwegian Children

Randi J. Bertelsen, Karin C. Lødrup Carlsen, Antonia M. Calafat, Jane A. Hoppin, Geir Håland, Petter Mowinckel, Kai-Håkon Carlsen, and Martinus Løvik | 251-256

Prenatal p,p´-DDE Exposure and Neurodevelopment among Children 3.5–5 Years of Age

Luisa Torres-Sánchez, Lourdes Schnaas, Stephen J Rothenberg, Mariano E. Cebrián, Erika Osorio-Valencia, María del Carmen Hernández, Rosa María García-Hernández, and Lizbeth López-Carrillo | 263-268

In Utero Pesticide Exposure and Leukemia in Brazilian Children < 2 Years of Age

Jeniffer Dantas Ferreira, Arnaldo Cézar Couto, Maria S. Pombo-de-Oliveira, Sergio Koifman, and the Brazilian Collaborative Study Group of Infant Acute Leukemia | 269-275

In Utero and Childhood Polybrominated Diphenyl Ether (PBDE) Exposures and Neurodevelopment in the CHAMACOS Study

Brenda Eskenazi, Jonathan Chevrier, Stephen A. Rauch, Katherine Kogut, Kim G. Harley, Caroline Johnson, Celina Trujillo, Andreas Sjödin, and Asa Bradman | 257-262

Characterization of Residential Pesticide Use and Chemical Formulations through Self-Report and Household Inventory: The Northern California Childhood Leukemia Study

Neela Guha, Mary H. Ward, Robert Gunier, Joanne S. Colt, C. Suzanne Lea, Patricia A. Buffler, and Catherine Metayer | 276-282

Perspectives