MacVector is a sequence analysis application that provides users with a variety of tools and functions to simplify the analysis, manipulation, assembly and documentation of DNA and protein sequences.

Key Features

  • Graphical Sequence Editing assists users with reading and writing DNA and protein sequences in most file formats.
  • The Gateway and Topo Cloning feature uses a graphical interface to help users replicate biological manipulations to create new molecules with the correct sequences across the cloning and recombination junctions.
  • The Primer Design feature allows users to design primers for either PCR or Sequencing/Hybridization probes.
  • MacVector includes DNA Analysis tools such as base composition analysis, restriction enzyme searches, DNA subsequence searches and “Dot-Plot” comparisons between DNA:DNA and DNA:protein sequences.
  • Protein Analysis features help users reverse translate protein sequences into DNA, compare using “Dot-Plot” analysis and scan for proteolytic cleavage sites and amino acid sequence motifs.
  • Database Searching feature allows users to search using NCBI BLAST and Entrez databases.
  • The Multiple Sequence Alignment feature helps users align any number of sequences, and provides a sophisticated editor for fine tuning the alignments.
  • The Sequence Assembly module allows users to import trace files, or sequence files to assemble using a template.

To purchase MacVector, please contact your ISDP IC/Agency Contact. If you have any questions feel free to email us at nihisdp@mail.nih.gov.

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