Question ID: WS-49
Submitted by: Deadly Cancer Coalition
February 8, 2011
Question: Can we develop a systematic molecular classification of the deadliest cancer types? Background: Understanding the driving molecular pathways (e.g. Bcr/Abl in CML or Her2 in breast cancer) has helped us to develop effective targeted therapeutics. Feasibility: Research that develops a systematic method for molecular definition and classification of all cancers – correlated to historic phenotypic and anatomic origins of the specific cancer types and also to the available genomic information – can stimulate many aspects of fundamental cancer research that may be vital to finding better diagnostic markers and targeted therapeutics.
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