NIH Clinical Research Studies Listed By Institute of the Principal Investigator

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

23 Protocols (15 Active Accrual of new subjects, 8 Follow-up of previously enrolled subjects)


Active Accrual, Protocols Recruiting New Patients 
* 13-AR-0056:
Stopping Tumor Necrosis Factor-Alpha Inhibitors in Rheumatoid Arthritis

* 13-AR-0005:
A Phase 1b, Randomized, Double-Blind, Placebo Controlled Study with an Open Label Extension to Evaluate the Safety and Tolerability of Omalizumab, A Humanized IgG1 Monoclonal Antibody in Patients with Lupus (STOP LUPUS)

* 11-AR-0241:
A Pilot Study of Anakinra in Behcet's Disease (BD)

* 11-AR-0223:
Studies on the Natural History and Pathogenesis of Spondyloarthritis

* 11-AR-0156:
Bisphosphonate Users Radiographic Characteristics of the Hip (BURCH) Study

* 04-AR-0205:
Progression of Spinal Fusion in Ankylosing Spondylitis

* 03-AR-0298:
A Long-Term Outcome Study with the IL-1 Receptor Antagonist anakinra/Kineret(Registered Trademark) in Patients with Neonatal Onset Multisystem Inflammatory Disease (NOMID/CINCA Syndrome) A Therapeutic Approach to Study the Pathogenesis of this Disease

* 03-AR-0173:
Studies of the Natural History, Pathogenesis, and Outcome of Autoinflammatory Diseases (NOMID/CAPS, DIRA, CANDLE, CRMO, Still's Disease, Behcet's Disease, and other Undifferentiated Autoinflammatory Diseases)

* 03-AR-0131:
Genetic Determinants of Ankylosing Spondylitis Severity - Longitudinal Study

* 02-AR-0131:
Collection Of Blood Components Using Apheresis from Patients with Rheumatic Diseases and Healthy Volunteers

* 01-AR-0227:
Studies of the Natural History of Rheumatic Disease in Minority Communities

* 00-AR-0222:
Studies of the Pathogenesis and Natural History of Arthritis and Related Conditions

* 99-AR-0004:
Molecular Basis of Primary Immunodeficiencies

* 94-AR-0066:
Studies of the Pathogenesis and Natural History of Systemic Lupus Erythematosus (SLE)

* 91-AR-0196:
Studies on the Natural History and Pathogenesis of Polymyositis, Dermatomyositis, and Related Diseases

Active Follow-up, Protocols NOT Recruiting New Patients 

* 09-AR-0006:
A Multi-Center, Open Label, 24-Month Treatment Study to Establish the Safety, Tolerability, Efficacy, Pharmacokinetics and Pharmacodynamics of Canakinumab (anti-IL-1 Beta Antibody) in Patients with NOMID / CINCA Syndrome

* 08-AR-0218:
Phase II Trial of Rilonacept for Treatment of Familial Mediterranean Fever (FMF)

* 08-AR-0008:
Insulin Resistance and Atherosclerosis in a Sample of Women with Systemic Lupus Erythematosus

* 05-AR-0014:
Continuation of a Pilot Open-Label Study of IL 1 Trap in Adult Subjects with Autoinflammatory Disease: A Therapeutic Approach to Study Pathogenesis

* 03-AR-0133:
Clinically Important Changes in Rheumatoid Arthritis

* 03-AR-0130:
Genetic Determinants of Ankylosing Spondylitis Severity - Cross Sectional Study

* 02-AR-0272:
A Phase I, Open-Labeled, Dose-Ascending Clinical Trial of Immunotherapy of MRA, A Humanized Anti-IL 6 Receptor Monoclonal Antibody, In Patients with Systemic Lupus Erythematosus

* 02-AR-0156:
A Randomized, Double-Blind, Placebo-Controlled Trial of Infliximab in Patients with Dermatomyositis and Polymyositis

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