National Institute of Neurological Disorders and Stroke (NINDS)

102 Protocols (74 Active Accrual of new subjects, 28 Follow-up of previously enrolled subjects)

 13-N-0076:

Gamma Frequency Transcranial Magnetic Stimulation in Dystonia

 13-N-0047:

Treatment of Functional Movement Disorders with Psychotherapy

 13-N-0035:

Modulating Behavior in Humans by Entrainment with Rhythmic Transcranial Magnetic Stimulation

 13-N-0022:

Placebo Controlled Double Blind Study of Acetyl Hexapeptide-8 in Treatment of Blepharospasm

 13-N-0017:

Natural History Study of Progressive Multifocal Leukoencephalopathy (PML)

 13-N-0008:

Sildenafil for Cerebrovascular Dysfunction in Chronic Traumatic Brain Injury

 12-N-0182:

Positron Emission Tomography Measurement of Neuroinflammation and P-glycoprotein in Localization-Related Epilepsy

 12-N-0137:

A Phase 1 Open-Label Dose Escalation Safety Study of Convection Enhanced Delivery (CED) of Adeno-Associated Virus Encoding Glial Cell Line-Derived Neurotrophic Factor (AAV2-GDNF) in Subjects with Advanced Parkinson's Disease

 12-N-0123:

Succinic Semialdehyde Dehydrogenase Deficiency: Physiological Markers of Taurine Therapy

 12-N-0122:

Integrating Genetic and Environmental Risk Scores into an Algorithm to Predict Multiple Sclerosis Susceptibility

 12-N-0104:

Validating a New Writer's Cramp Scale

 12-N-0095:

Clinical and Molecular Manifestations of Neuromuscular and Neurogenetic Disorders of Childhood

 12-N-0065:

Experienced Breacher Study: Evaluation of the Effects from Chronic Exposure to Low-Level Blast

 12-N-0060:

Structural and Functional Brain Imaging Markers of Upper Motor Neuron Function

 12-N-0033:

A Phase Two Clinical Trial of Buspirone Therapy in Localization-Related Epilepsy

 12-N-0031:

Imaging Biomarkers in Parkinson Disease

 12-N-0030:

Fatigue and Amotivation Following Mild Traumatic Brain Injury and their Influence on Service Member Community Reintegration

 12-N-0007:

Prospective Evaluation of the Effect of Corticotropin-Releasing Hormone Stimulation on 18F-Fludeoxyglucose High-Resolution Positron-Emission Tomography in Cushing's Disease

 11-N-0261:

Evaluation of Skeletal Muscle, Cardiac, and Diaphragm Imaging Biomarkers for GSK2402968 Effects in Ambulatory Boys with Duchenne Muscular Dystrophy

 11-N-0211:

Deep Brain Stimulation Surgery for Movement Disorders

 11-N-0204:

Prospective, Randomized Controlled Trial of Surgical Resection Prior to Bevacizumab Therapy for Recurrent Glioblastoma Multiforme

 11-N-0182:

The Role of the Inferior Frontal Gyrus in Long-Term Auditory Memory - a rTMS Study

 11-N-0171:

Effect of Functional Exercise in Patients with Spinal and Bulbar Muscular Atrophy

 11-N-0084:

Evaluation and Diagnosis of Potential Research Subjects with Traumatic Brain Injury (TBI)

 11-N-0055:

The Effect of Transcranial Magnetic Stimulation on Learning with Reward in Healthy Humans

 11-N-0051:

Surgery as a Treatment for Medically Intractable Epilepsy

 11-N-0039:

A Phase II Clinical Trial of PRX-00023 Therapy in Localization-Related Epilepsy

 10-N-0212:

Double Blind Combination of Rituximab by Intravenous and Intrathecal Injection Versus Placebo in Patients with Low-Inflammatory Secondary Progressive Multiple Sclerosis (RIVITaLISe)

 10-N-0199:

Ethanol Response in Essential Tremor: Clinical and Neurophysiological Correlates

 10-N-0193:

Using Positron Emission Tomography (PET) to Predict Intracranial Tumor Growth in Neurofibromatosis Type II (NF2) Patients

 10-N-0143:

A Prospective Natural History Study of Patients with Syringomyelia

 10-N-0057:

The Influence of Sensory Stimuli on Gait Imagery in Patients with Freezing of Gait

 10-N-0009:

Physiological Investigations of Movement Disorders

 10-N-0003:

Recording and Modulation of Neuronal Mechanisms During Operant Conditioning: A MEG Study

 09-N-0197:

Double Blind Placebo-Controlled Phase I/II Clinical Trial of Idebenone in Patients with Primary Progressive Multiple Sclerosis

 09-N-0182:

GABA/Glutamate Balance in Temporal Lobe Epilepsy with and without Major Depression

 09-N-0118:

Investigation of Neurofeedback with Real-Time fMRI in Healthy Volunteers and Patients with Hyperkinetic Movement Disorders

 09-N-0117:

An Open Label Dose Escalation Safety Study of Convection-Enhanced Delivery of IL13-PE38QQR in Patients with Progressive Pediatric Diffuse Infiltrating Brainstem Glioma and Supratentorial High-Grade Glioma

 09-N-0032:

Comprehensive Multimodal Analysis of Neuroimmunological Diseases of the CNS

 09-N-0010:

Biomarkers of Risk of Parkinson Disease

 08-N-0215:

Understanding the Anatomy and Physiology of the Sensory Experience and its Role in Generating Tics in Tourette Syndrome

 08-N-0161:

Noninvasive Language Mapping in Patients with Localization-Related Epilepsy

 08-N-0153:

The Role of Autoimmunity in Neurologic Complications of Celiac Disease

 08-N-0044:

A Prospective Natural History Study of Patients with Neurofibromatosis Type 2 (NF2)

 08-N-0027:

HHV6B in Epilepsy Imaging and CSF Studies

 07-N-0190:

Neurobiological Studies of Psychogenic Movement Disorders and Non-Epileptic Seizures

 07-N-0137:

Expanding the Phenotype of the LRRK-2 Mutation in Individuals with History of Parkinson's Disease and their Relatives: a Prospective Study

 07-N-0103:

Imaging Serotoninergic Neurotransmission in Epilepsy

 07-N-0092:

PET Evaluation of Brain Peripheral Benzodiazepine Receptors Using [(11)C]PBR28 in Patients with Multiple Sclerosis (MS)

 07-N-0063:

Detecting a Reward Signal in the Motor Cortex

 06-N-0224:

Collection of Blood Samples for DNA Analysis in Motor Neuron Diseases

 06-N-0161:

Long-Term Motor Learning in Focal Hand Dystonia

 06-N-0085:

Two-Compartment Model of Diffusion Tensor Magnetic Resonance Imaging (DT-MRI) for the Diagnosis of Glioma Tumor Recurrence versus Radiation Necrosis

 06-N-0047:

Reference Values for Plasma Catechols

 05-N-0228:

The Role of Cortical Coherence in Focal Hand Dystonia

 05-N-0223:

Clinical Neurophysiology: Training and Normative Values

 04-N-0071:

Phase I/II Study of HTLV-I-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP) Using the Humanized MiK-Beta-1 Monoclonal Antibody Directed Toward the IL-2/IL-15R-Beta Subunit (CD122) that Blocks IL-15 Action

 03-N-0164:

Evaluation and Treatment of Neurosurgical Disorders

 03-N-0004:

Clinical Laboratory Evaluation of Primary Chronic Autonomic Failure

 02-N-0132:

In Vivo Mapping Of Structural and Biochemical Abnormalities In Patients With Primary Focal Dystonia

 02-N-0128:

Evaluation of Tourette's Syndrome with Multimetabolite H-Magnetic Resonance Spectroscopy at 3T

 02-N-0014:

Research Study of Specimens Obtained During Epilepsy Surgery

 01-N-0206:

Phenotype/Genotype Correlations in Movement Disorders

 01-N-0145:

Screening and Natural History: Primary Lateral Sclerosis and Related Disorders

 01-N-0139:

Evaluation and Treatment of Patients with Epilepsy

 01-N-0007:

Evaluation, Pathogenesis, and Treatment of Patients with or at Risk for Cerebrovascular Disease (A Natural History/Disease Pathogenesis Protocol)

 00-N-0158:

Trial of Intracerebral Infusion in Patients with Medically Intractable Epilepsy

 00-N-0089:

Genetic Analysis of the Chiari I Malformation

 00-N-0082:

Characterization of Brain Morphology and Activity Using Functional and Anatomical MRI Contrast

 00-N-0043:

Clinical and Molecular Manifestations of Inherited Neurological Disorders

 98-N-0047:

Immuno-Virological Evaluation of Human T Cell Leukemia Virus Type-1 Associated Myelopathy (HAM/TSP)

 93-N-0202:

Diagnosis and Natural History Protocol for Patients with Different Neurological Conditions

 89-N-0045:

Evaluation of Progression in Multiple Sclerosis by Magnetic Resonance Imaging (MRI)

 85-N-0195:

A Training Protocol for the use of Botulinum Toxin in the Treatment of Neurological Disorders

 12-N-0012:

Pilot Study of Bilateral Pedunculo-Pontine Nucleus (PPN) Deep Brain Stimulation for Patients with Parkinson Disease (PD) Who Have Persistent Gait Disturbance, Despite Bilateral Subthalamic Nucleus (STN) Deep Brain Stimulation

 11-N-0210:

NIB Repository Protocol

 11-N-0157:

Analysis of Visual-Motor Task Electrophysiological Activity During Deep Brain Stimulation for Treatment-Resistant Obsessive-Compulsive and Movement Disorders

 11-N-0116:

Manganese-Enhanced Magnetic Resonance Imaging in Healthy Volunteers and People with Multiple Sclerosis

 11-N-0090:

Structural and Functional Neuroimaging Studies of Combat Veterans

 10-N-0185:

Neural Dynamics and Connectivity in Response Inhibition and Traumatic Brain Injury

 10-N-0125:

Investigating Mechanism of Action of DAC HYP in the Treatment of High-Inflammatory Multiple Sclerosis (MS)

 10-N-0121:

Oxidative Stress in Motor Neuron Disease: COSMOS-PLS Add-On Study

 10-N-0092:

Genetics of Motor Learning

 10-N-0012:

Screening Protocol for Patients with Stroke

 09-N-0160:

Convection Enhanced Delivery of Muscimol to Study the Pathophysiology Underlying the Clinical Features of Parkinson's Disease

 08-N-0181:

Role of Neurotransmission and Functional CNS Networks in Spasmodic Dysphonia and Other Focal Dystonias

 08-N-0134:

Pilot Study of Tolerability of Lithium Therapy in Patients with Spinocerebellar Ataxia Type I (SCA1)

 08-N-0012:

L-Dihydroxyphenylserine (L-DOPS) for Norepinephrine Deficiency: Interactions with Carbidopa and Entacapone

 07-N-0122:

of Motor Function by Stimulation of the Central and Peripheral Nervous System

 07-N-0072:

Neural Substrates of Lasting Motor Skill Learning by Spacing Effect

 06-N-0174:

Cortical Function in Primary Lateral Sclerosis and Amyotrophic Lateral Sclerosis

 06-N-0138:

Long-Term Improvement in Training Effects by Transcranial DC Stimulation

 06-N-0113:

Phase II Clinical Trial to Examine the Efficacy and Safety of Dutasteride in Patients with Kennedy's Disease (Spinal and Bulbar Muscular Atrophy)

 06-N-0012:

Moving a Paralyzed Hand through a Brain-Computer Interface Controlled by the Affected Hemisphere After Stroke or Traumatic Brain Injury

 05-N-0245:

A Six Month Double-Blind, Placebo-Controlled Phase 2 Clinical Trial to Determine the Safety and Efficacy of Idebenone Administered to Patients with Friedreich's Ataxia

 05-N-0189:

Neuropathological Basis of Spasmodic Dysphonia and Related Voice Disorders

 05-N-0179:

MRI Measurement of Brain Metabolism Across the Sleep-Wake Cycle

 05-N-0063:

NINDS Biomarkers in Multiple Sclerosis Study (BioMS)

 03-N-0293:

Induction of Mucosal Tolerance to Human E-Selectin for the Secondary Prevention of Stroke

 03-N-0203:

SMN Levels in Peripheral Blood Samples of SMA Patients and the Effects of Pharmacological Compounds In Vitro

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