The National Institute of Diabetes & Digestive & Kidney Diseases

Type 1 Diabetes: Prevention

This program includes studies on drug development, and cellular therapy that are being proposed to prevent type 1 diabetes.

Areas of particular interest are:

• Studies on drug development for type 1 diabetes treatment or prevention:
• Studies including the creation of animal models for therapy trials or humans to maintain normal blood glucose levels.
• Tolerance induction for prevention of type 1 diabetes
• Immune intervention
• "Humanized" mouse model (development of transgenic NOD with human HLA molecules on the T cells) for type 1 diabetes
• Development of therapies for prevention of Impaired Glucose Tolerance (IGT) or interventions to prevent conversion of IGT to type 1 diabetes
• Drugs designed to enhance peripheral glucose metabolism or reduce hepatic glucose production of type 1 diabetics
• Therapies designed to increase insulin sensitivity of type 1 diabetics

For more information, contact Dr. Beena Akolkar, Immunopathogenesis and Genetics of Type 1 Diabetes Program Director.

Resources for Researchers Databases, Registries and Information Basic Research Networks Reagents Services Standardization Programs Tissues, Cells, Animals Useful Tools Clinical Research Search for Clinical Trials Multicenter Clinical Research Centers All NIDDK Centers Related Study Sections Hypersensitivity, Autoimmune, and Immune-mediated Diseases Study Section [HAI] Transplantation, Tolerance and Tumor Immunology Study Section [TTT] NIDDK Staff Dr. Beena Akolkar, Immunopathogenesis and Genetics of Type 1 Diabetes Program Director Dr. Michael Appel, Director, Islet Biology and Transplantation Research Program Dr. Catherine Cowie, Director, Diabetes Epidemiology Program Dr. Edward Doo, Director of the Liver Diseases Program Dr. Michael Flessner, Inflammatory Kidney Diseases Program Director Dr. Frank Hamilton, Gastrointestinal Mucosa and Immunology Program Director. Dr. Ellen Leschek, Type 1 Diabetes Trialnet Program Director Dr. Jose Serrano, Director of the Liver and Biliary Program; Director of the Pancreas Program Dr. Lisa Spain, Director, Immunobiology of Type 1 Diabetes Program and Autoimmune Endocrine Diseases Program Dr. Susan Yanovski, Co-Director, Office of Obesity Research See Also Diabetes Research at NIDDK Digestive Diseases at NIDDK National Institute of Allergy and Infectious Diseases Medline Plus: Immune System and Disorders

Funding Opportunities All NIDDK PAs, RFAs, and Notices Immunological Diseases Research PAs General NIDDK PAs Funding for Special Communities Training and Careers Small Business Conferences Conference Grant support Upcoming Past Immunological Diseases Conference Reports Related Reports Action Plan for Liver Disease Research January 18-19, 2005 - Expert Panel Meeting on the Special Statutory Funding Program for Type 1 Diabetes Research - Meeting Summary (PDF, 530KB) Type 1 Diabetes Research Special Statutory Funding Program Report on Progress & Opportunities The Type 1 Diabetes Research Strategic Plan Related Organizations Juvenile Diabetes Research Foundation International Center for the Study of Inflammatory Bowel Disease (CSIBD) Crohn's & Colitis Foundation of America Broad Medical Research Program

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Page last updated: February 01, 2011