The Pediatric Kidney Disease program would encompass any interventional, epidemiological, descriptive, natural history studies of children with acute or chronic renal diseases. Specific areas to be included:
Congenital and hereditary disorders in children – renal dysplasia, cystic kidney diseases; congenital nephrotic syndrome, hereditary glomerulopathy, Alport syndrome; metabolic disorders such as cystinosis. Cystinuria, hyperoxaluria, Fanconi syndrome; primary and secondary kidney involvement in disorders of phosphorus, calcium and vitamin D; tubular disorders of electrolyte transport and regulation such as Bartter’s syndrome, Liddle’s syndrome, renal tubular acidosis.
Glomerulonephritides in children – minimal change nephrotic syndrome, focal segmental glomerulosclerosis, membranoproliferative glomerulonephritis, IgA nephropathy, and hemolytic uremic syndrome. Lupus nephritis is covered under the Inflammatory Kidney Disease Program.
Acute renal failure in children – natural history or treatment interventions.
Pediatric chronic kidney disease and End Stage Renal Disease (ESRD) – treatment interventions for slowing disease progression and for the complications of chronic kidney disease, including dialysis and transplantation. Areas of interest would include nutritional management, growth and growth failure, cardiovascular complications, neurocognitive complications, disease recurrence post-transplant, and complications post-transplantation.
Renal Function Assessment in Children – studies of methods to accurately measure glomerular filtration rate (invasive or surrogate, noninvasive methods), urinary protein excretion; renal biopsy techniques and tissue assessment; renal imaging.
For more information, contact Dr. Marva Moxey-Mims, Program Director, Pediatric Nephrology.
