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Recently Published Research

• Traffic-Related Air Pollution, Particulate Matter, and Autism  [Abstract] (http://archpsyc.jamanetwork.com/article.aspx?articleid=1393589#qundefined)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2013/1/dert/index.htm#a2)  Volk HE, Lurmann F, Penfold B, Hertz-Picciotto I, McConnell R.  January 2013

• Functional Regulation of ClC-3 in the Migration of Vascular Smooth Muscle Cells  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/23150504)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2013/1/dir/index.htm#a1)  Ganapathi SB, Wei SG, Zaremba A, Lamb FS, Shears SB.  January 2013

• Transactivating Function (AF) 2-Mediated AF-1 Activity of Estrogen Receptor Alpha is Crucial to Maintain Male Reproduction Tract Function  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/23213263)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2013/2/dir/index.htm#a1)  Arao Y, Hamilton KJ, Goulding EH, Janardhan KS, Eddy EM, Korach KS.  December 2012

• Mechanism of Repair of 5’-Topoisomerase II-DNA Adducts by Mammalian Tyrosyl-DNA Phosphodiesterase 2  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/23104055)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2013/1/dir/index.htm#a2)  Schellenberg MJ, Appel CD, Adhikari S, Robertson PD, Ramsden DA, Williams RS.  December 2012

• Household Light Makes Global Heat: High Black Carbon Emissions from Kerosene Wick Lamps  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/23163320)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2013/2/dert/index.htm#a1)  [Story] (http://www.niehs.nih.gov/news/newsletter/2013/1/science-kerosene/index.htm)  Lam NL, Chen Y, Weyant C, Venkataraman C, Sadavarte P, Johnson MA, Smith KR, Brem BT, Arineitwe J, Ellis JE, Bond TC.  December 2012

• The Toll-like Receptor 5 Ligand Flagellin Promotes Asthma by Priming Allergic Responses to Indoor Allergens  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/23064463)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/12/dir/index.htm#a4)  Wilson RH, Maruoka S, Whitehead GS, Foley JF, Flake GP, Sever ML, Zeldin DC, Kraft M, Garantziotis S, Nakano H, Cook DN.  November 2012

• Migratory Properties of Pulmonary Dendritic Cells are Determined by Their Developmental Lineage  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/23168837)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2013/1/dir/index.htm#a3)  Nakano H, Burgents JE, Nakano K, Whitehead GS, Cheong C, Bortner CD, Cook DN.  November 2012

• Exposure to Tobacco Smoke In Utero and Subsequent Plasma Lipids, ApoB, and CRP Among Adult Women in the MoBa Cohor  [Abstract] (http://ehp.niehs.nih.gov/2012/11/1104563/)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2013/1/dir/index.htm#a4)  Cupul-Uicab LA, Skjaerven R, Haug K, Travlos GS, Wilson RE, Eggesbo M, Hoppin JA, Whitworth KW, Longnecker MP  November 2012

• An Ultraviolet-Radiation-Independent Pathway to Melanoma Carcinogenesis in the Red Hair/Fair Skin Background  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/23123854)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2013/1/dert/index.htm#a1)  Mitra D, Luo X, Morgan A, Wang J, Hoang MP, Lo J, Guerrero CR, Lennerz JK, Mihm MC, Wargo JA, Robinson KC, Devi SP, Vanover JC, D’Orazio JA, McMahon M, Bosenberg MW, Haigis KM, Haber DA, Wang Y, Fisher DE.  November 2012

• Accumulation and Endocrine Disrupting Effects of the Flame Retardant Mixture Firemaster® 550 in Rats: An Exploratory Assessment  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/23139171)   [Synopsis] (Accumulation and Endocrine Disrupting Effects of the Flame Retardant Mixture Firemaster® 550 in Rats: An Exploratory Assessment)  Patisaul HB, Roberts SC, Mabrey N, McCaffrey KA, Gear RB, Braun J, Belcher SM, Stapleton HM.  November 2012

• Reversible Switching Between Epigenetic States in Honeybee Behavioral Subcastes  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22983211)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/11/dert/index.htm#a2)  Herb BR, Wolschin F, Hansen KD, Aryee MJ, Langmead B, Irizarry R, Amdam GV, Feinberg AP.  October 2012

• RAP80 Is Critical in Maintaining Genomic Stability and Suppressing Tumor Development  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22896338)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/12/dir/index.htm#a1)  Yin Z, Menendez D, Resnick MA, French JE, Janardhan KS, Jetten AM.  October 2012

• Prenatal Exposure to Mercury and Fish Consumption During Pregnancy and Attention-Deficit/Hyperactivity Disorder-Related Behavior in Children  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/23044994)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2013/1/dert/index.htm#a4)  Sagiv SK, Thurston SW, Bellinger DC, Amarasiriwardena C, Korrick SA.  October 2012

• Maternal Urinary Bisphenol A during Pregnancy and Maternal and Neonatal Thyroid Function in the CHAMACOS Study  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/23052180)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/12/dert/index.htm#a1)  Chevrier J, Gunier RB, Bradman A, Holland NT, Calafat AM, Eskenazi B, Harley KG.  October 2012

• Glucocorticoids Regulate Arrestin Gene Expression and Redirect the Signaling Profile of G Protein-Coupled Receptors  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/23045642)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/12/dir/index.htm#a3)  Oakley RH, Revollo J, Cidlowski JA.  October 2012

• DNA Sequence Context Effects on the Glycosylase Activity of Human 8-oxoguanine DNA Glycosylase  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22989888)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/12/dir/index.htm#a2)  Sassa A, Beard WA, Prasad R, Wilson SH.  October 2012

• Coplanar Polychlorinated Biphenyls Impair Glucose Homeostasis in Lean C57BL/6 Mice and Mitigate Beneficial Effects of Weight Loss on Glucose Homeostasis in Obese Mice  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/23099484)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/12/dert/index.htm#a2)  Baker NA, Karounos M, English V, Fang J, Wei Y, Stromberg A, Sunkara M, Morris AJ, Swanson HI, Cassis LA.  October 2012

• Bisphenol A Alters Early Oogenesis and Follicle Formation in the Fetal Ovary of the Rhesus Monkey  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/23012422)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/11/dert/index.htm#a3)  Hunt PA, Lawson C, Gieske M, Murdoch B, Smith H, Marre A, Hassold T, Vandevoort CA.  October 2012

• Targeting Blood-Brain Barrier Sphingolipid Signaling Reduces Basal P-glycoprotein Activity and Improves Drug Delivery to the Brain  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22949658)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/11/dir/index.htm#a1)  Cannon RE, Peart JC, Hawkins BT, Campos CR, Miller DS.  September 2012

• Systematic Localization of Common Disease-Associated Variation in Regulatory DNA  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22955828)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/11/dert/index.htm#a1)  Maurano MT, Humbert R, Rynes E. Thurman RE, Haugen E, Wang H, Reynolds AP, Sandstrom R, Qu H, Brody J, Shafer A, Neri F, Lee K, Kutyavin T, Stehlink-Sun S, Johnson AK, Canfield TK, Giste E, Diegel M, Bates D, Hansen RS, Neph S, Sabo PJ, Heimfeld S, Raubitschek A, Ziegler S, Cotsapas C, Sotoodehnia N, Glass I, Sunyaev SR, Kaul R, Stamatoyannopoulos JA.  September 2012

• Low-Level p53 Expression Changes Transactivation Rules and Reveals Superactivating Sequences  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22908277)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/11/dir/index.htm#a4)  Jordan JJ, Menendez D, Sharav J, Beno I, Rosenthal K, Resnick MA, Haran TE.  September 2012

• Infant Origins of Childhood Asthma Associated with Specific Molds  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22789397)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/10/dert/index.htm#a4)  Reponen T, Lockey J, Bernstein DI, Vesper SJ, Levin L, Khurana Hershey GK, Zheng S, Ryan P, Grinshpun SA, Villareal M, Lemasters G.  September 2012

• Dioxin (TCDD) Induces Epigenetic Transgenerational Inheritance of Adult Onset Disease and Sperm Epimutations  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/23049995)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/12/dert/index.htm#a4)  Manikkam M, Tracey R, Guerrero-Bosagna C, Skinner MK.  September 2012

• Cholinergic Coordination of Presynaptic and Postsynaptic Activity Induces Timing-Dependent Hippocampal Synaptic Plasticity  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22956824)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/11/dir/index.htm#a2)  Gu Z, Lamb PW, Yakel JL.  September 2012

• Childhood Air Pollutant Exposure and Carotid Artery Intima-Media Thickness in Young Adults  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22896588)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/12/dert/index.htm#a3)  Breton CV, Wang X, Mack WJ, Berhane K, Lopez M, Islam TS, Feng M, Lurmann F, McConnell R, Hodis HN, Kunzli N, Avol E.  September 2012

• A Major Environmental Cause of Death  [Abstract] (http://www.sciencemag.org/content/334/6053/180)   [Full Article]  [Special Issue]   William J. Martin II, Roger I. Glass, John M. Balbus, Francis S. Collins.  September 2012

• Altered Pattern of Immunoglobulin Hypermutation in Mice Deficient in Slip-GC Protein  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22833677)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/10/dir/index.htm#a2)  Richter K, Burch L, Chao F, Henke D, Jiang C, Daly J, Zhao ML, Kissling G, Diaz M.  September 2012

• Triclosan Impairs Excitation-Contraction Coupling and Ca2+ Dynamics in Striated Muscle  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22891308)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/10/dert/index.htm#a1)  Cherednichenko G, Zhang R, Bannister RA, Timofeyev V, Li N, Fritsch EB, Feng W, Barrientos GC, Schebb NH, Hammock BD, Beam KG, Chiamvimonvat N, Pessah IN.  August 2012

• The Human TLR Innate Immune Gene Family is Differentially Influenced by DNA Stress and p53 Status in Cancer Cells  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22673234)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/10/dir/index.htm#a4)  Shatz M, Menendez D, Resnick MA.  August 2012

• Relation Between Objective Measures of Atopy and Myocardial Infarction in the United States  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22921873)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/10/science-allergymi/index.htm)  Jaramillo R, Cohn RD, Crockett PW, Gowdy KM, Zeldin DC, Fessler MB.  August 2012

• Red Meat and Poultry, Cooking Practices, Genetic Susceptibility and Risk of Prostate Cancer: Results from a Multiethnic Case-Control Study  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22822096)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/10/dert/index.htm#a2)  Joshi AD, Corral R, Catsburg C, Lewinger JP, Koo J, John EM, Ingles SA, Stern MC.  August 2012

• Mitochondrial Dysfunction in Pten Haplo-Insufficient Mice with Social Deficits and Repetitive Behavior: Interplay between Pten and p53.  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22900024)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/10/dert/index.htm#a3)  Napoli E, Ross-Inta C, Wong S, Hung C, Fujisawa Y, Sakaguchi D, Angelastro J, Omanska-Klusek A, Schoenfeld R, Giulivi C.  August 2012

• Gestational Exposure to Bisphenol A Produces Transgenerational Changes in Behaviors and Gene Expression  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22707478)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/8/dert/index.htm#a3)  Wolstenholme JT, Edwards M, Shetty SR, Gatewood JD, Taylor JA, Rissman EF, Connelly JJ.  August 2012

• Evolutionary History and Adaptation from High-coverage Whole-genome Sequences of Diverse African Hunter-gatherers  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22840920)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/9/dert/index.htm#a1)  Lachance J, Vernot B, Elbers CC, Ferwerda B, Froment A, Bodo JM, Lema G, Fu W, Nyambo TB, Rebbeck TR, Zhang K, Akey JM, Tishkoff SA.  August 2012

• A Quantitative Assay for Assessing the Effects of DNA Lesions on Transcription  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22902614)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/11/dert/index.htm#a4)  You C, Dai X, Yuan B, Wang J, Wang J, Brooks PJ, Niedernhofer LJ, Wang Y  August 2012

• Urinary Naphthol Metabolites and Chromosomal Aberrations in 5-Year-Old Children  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22573794)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/8/dert/index.htm#a1)  Orijuela MA, Liu X, Miller RL, Warburton D, Tang D, Jobanputra V, Hoepner L, Suen IH, Diaz-Carreno S, Li Z, Sjodin A, Perera FP.  July 2012

• Prevalence and Sociodemographic Correlates of Antinuclear Antibodies in the United States  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22237992)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/9/dir/index.htm#a3)  Satoh M, Chan EK, Ho LA, Rose KM, Parks CG, Cohn RD, Jusko TA, Walker NJ, Germolec DR, Whitt IZ, Crockett PW, Pauley BA, Chan JY, Ross SJ, Birnbaum LS, Zeldin DC, Miller FW.  July 2012

• Hypomethylation of Dual Specificity Phosphatase 22 Promoter Correlates with Duration of Service in Firefighters and is Inducible by Low-dose Benzo(a) Pyrene  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22796920)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/9/dert/index.htm#a3)  Ouyang B, Baxter CS, Lam HM, Yeramaneni S, Levin L, Haynes E, Ho SM.  July 2012

• Fungal and Atopic Sensitization Are Low Among Farmers in the Agricultural Health Study  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22633325)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/8/dir/index.htm#a1)  Endres SM, Green BJ, Henneberger PK, Germolec DR, Bledsoe TA, Beezhold DH, London SJ, Alavanja MC, Beane Freeman LE, Hoppin JA.  July 2012

• Fertility Drugs and Young-onset Breast Cancer: Results from the Two Sister Study  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22773825)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/9/dir/index.htm#a2)  Fei C, DeRoo LA, Sandler DP, Weinberg CR.  July 2012

• Detection and Imaging of the Free Radical DNA in Cells – Site-specific Radical Formation Induced by Fenton Chemistry and its Repair in Cellular DNA As Seen by Electron Spin Resonance, Immuno-spin Trapping and Confocal Microscopy  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22387463)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/9/dir/index.htm#a4)  Bhattacharjee S, Chatterjee S, Jiang J, Sinha BK, Mason RP.  July 2012

• Cerium Dioxide Nanoparticles Induce Apoptosis and Autophagy in Human Peripheral Blood Monocytes  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22717232)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/10/dir/index.htm#a3)  Hussain S, Al-Nsour F, Rice AB, Marshburn J, Yingling B, Ji Z, Zink JI, Walker NJ, Garantziotis S.  July 2012

• Cardiovascular Remodeling in Response to Long-term Exposure to Fine Particulate Matter Air Pollution  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22661498)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/9/dert/index.htm#a4)  Wold LE, Ying Z, Hutchinson KR, Velten M, Gorr MW, Velten C, Youtz DJ, Wang A, Lucchesi PA, Sun Q, Rajagopalan S.  July 2012

• A New Sensor for the Assessment of Personal Exposure to Volatile Organic Compounds  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22736952)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/9/dert/index.htm#a2)  Chen C, Campbell KD, Negi I, Iglesias RA, Owens P, Tao N, Tsow F, Forzani E.  July 2012

• 450K Epigenome-Wide Scan Identifies Differential DNA Methylation in Newborns Related to Maternal Smoking During Pregnancy  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22851337)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/10/dir/index.htm#a1)  [Story] (http://www.niehs.nih.gov/news/newsletter/2012/9/science-mechanism/index.htm)  Joubert BR, Haberg SE, Nilsen RM, Wang X, Vollset SE, Murphy SK, Huang Z, Hoyo C, Midttun O, Cupul-Uicab LA, Ueland PM, Wu MC, Nystad W, Bell DA, Peddada SD, London SJ.  July 2012

• STAT6 and LRP1 Polymorphisms are Associated with Food Allergen Sensitization in Mexican Children  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22534531)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/7/dir/index.htm#a3)  Hancock DB, Romieu I, Chiu GY, Sienra-Monge JJ, Li H, Estela Del Rio-Navarro B, London SJ.  June 2012

• RORgamma Directly Regulates the Circadian Expression of Clock Genes and Downstream Targets In Vivo  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22753030)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/9/dir/index.htm#a1)  Takeda Y, Jothi R, Birault V, Jetten AM.  June 2012

• Prenatal Exposure to Butybenzyl Phthalate and Early Eczema in an Urban Cohort  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22732598)   Just AC, Whyatt RM, Perzanowski MS, Calafat AM, Perera FP, Goldstein IF, Chen Q, Rundle AG, Miller RL.  June 2012

• Epigenetic Transgenerational Inheritance of Altered Stress Responses  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22615374)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/7/dert/index.htm#a3)  Crews D, Gillette R, Scarpino SV, Manikkam M, Savenkova MI, Skinner MK.  June 2012

• Altered Ig Hypermutation Pattern and Frequency in Complementary Mouse Models of DNA Polymerase Zeta Activity  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22547703)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/8/dir/index.htm#a2)  Daly J, Bebenek K, Watt DL, Richter K, Jiang C, Zhao ML, Ray M, McGregor WG, Kunkel TA, Diaz M.  June 2012

• Use of Metal Oxide Nanoparticle Band Gap to Develop a Predictive Paradigm for Oxidative Stress and Acute Pulmonary Inflammation  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22502734)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/7/dert/index.htm#a4)  Zhang H, Ji Z, Xia T, Meng H, Low-Kam C, Liu R, Pokhrel S, Lin S, Wang X, Liao YP, Wang M, Li L, Rallo R, Damoiseaux R, Telesca D, Mädler L, Cohen Y, Zink JI, Nel AE.  May 2012

• Regulating the Regulators: The Pervasive Effects of Pol II Pausing on Stimulus-Responsive Gene Networks  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22549956)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/7/dir/index.htm#a1)  Gilchrist DA, Fromm G, dos Santos G, Pham LN, McDaniel IE, Burkholder A, Fargo DC, Adelman K.  May 2012

• Identification of Novel NRF2-regulated Genes by ChIP-Seq: Influence on Retinoid X Receptor Alpha  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22581777)   Chorley BN, Campbell MR, Wang X, Karaca M, Sambandan D, Bangura F, Xue P, Pi J, Kleeberger SR, Bell DA.  May 2012

• Cnot1, Cnot2, and Cnot3 Maintain Mouse and Human ESC Identity and Inhibit Extraembryonic Differentiation  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22367759)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/5/dir/index.htm#a3)  Zheng X, Dumitru R, Lackford BL, Freudenberg JM, Singh AP, Archer TK, Jothi R, Hu G.  May 2012

• Clustered Mutations in Yeast and in Human Cancers Can Arise from Damaged Long Single-Strand DNA Regions  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22607975)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/7/dir/index.htm#a2)  Roberts SA, Sterling J, Thompson C, Harris S, Mav D, Shah R, Klimczak LJ, Kryukov GV, Malc E, Mieczkowski PA, Resnick MA, Gordenin DA.  May 2012

• Childhood Socioeconomic Factors and Perinatal Characteristics Influence Development of Rheumatoid Arthritis in Adulthood  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22586176)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/7/dir/index.htm#a4)  Parks CG, D’Aloisio AA, DeRoo LA, Huiber K, Rider LG, Miller FW, Sandler DP.  May 2012

• Association Between Changes in Air Pollution Levels During the Beijing Olympics and Biomarkers of Inflammation and Thrombosis in Healthy Young Adults  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22665106)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/7/dert/index.htm#a2)  Rich DQ, Kipen HM, Huang W, Wang G, Wang Y, Zhu P, Ohman-Strickland P, Hu M, Philipp C, Diehl SR, Lu SE, Tong J, Gong J, Thomas D, Zhu T, Zhang JJ.  May 2012

• Analysis of Chromatin Dynamics During Glucocorticoid Receptor Activation  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22451486)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/6/dir/index.htm#a1)  Burd CJ, Ward JM, Crusselle-Davis VJ, Kissling GE, Phadke D, Shah RR, Archer TK.  May 2012

• Alpha-Synuclein Genetic Variants Predict Faster Motor Symptom Progression in Idiopathic Parkinson Disease  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22615757)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/7/dert/index.htm#a1)  Ritz B, Rhodes SL, Bordelon Y, Bronstein J.  May 2012

• Urinary Bisphenol A Concentrations and Implantation Failure Among Women Undergoing In Vitro Fertilization  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22484414)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/6/dert/index.htm#a2)  Ehrlich S, Williams PL, Missmer SA, Flaws JA, Berry KF, Calafat AM, Ye X, Petrozza JC, Wright D, Hauser R.  April 2012

• Targeted Deletion of Nrf2 Impairs Lung Development and Oxidant Injury in Neonatal Mice  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22400915)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/5/dir/index.htm#a4)  Cho HY, van Houten B, Wang X, Miller-Degraff L, Fostel J, Gladwell W, Perrow L, Panduri V, Kobzik L, Yamamoto M, Bell DA, Kleeberger SR.  April 2012

• Summer Temperature Variability and Long-term Survival Among Elderly People with Chronic Disease  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22493259)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/5/dert/index.htm#a1)  Zanobetti A, O’Neill MS, Gronlund CJ, Schwartz JD.  April 2012

• Mismatch Repair-dependent Mutagenesis in Nondividing Cells  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22474380)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/6/dert/index.htm#a4)  Rodriguez GP, Romanova NV, Bao G, Rouf NC, Kow YW, Crouse GF.  April 2012

• Maternal Metabolic Conditions and Risk for Autism and Other Neurodevelopmental Disorders  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22492772)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/5/dert/index.htm#a2)  Krakowiak P, Walker CK, Bremer AA, Baker AS, Ozonoff S, Hansen RL, Hertz-Picciotto I.  April 2012

• Formation of Reactive Sulfite-derived Free Radicals by the Activation of Human Neutrophils: An ESR Study  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22326772)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/4/dir/index.htm#a3)  Ranguelova K, Rice AB, Khajo A, Triquigneaux M, Garantziotis S, Magliozzo RS, Mason RP.  April 2012

• Estrogen Receptor-Alpha Mediates Diethylstilbestrol-induced Feminization of the Seminal Vesicle in Male Mice  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22275727)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/4/dir/index.htm#a4)  Walker VR, Jefferson WN, Couse JF, Korach KS.  April 2012

• Environmental Estrogens Differentially Engage the Histone Methyltransferase EZH2 to Increase Risk of Uterine Tumorigenesis  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22504913)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/5/dert/index.htm#a4)  Greathouse KL, Bredfeldt T, Everitt JI, Lin K, Berry T, Kannan K, Mittelstadt ML, Ho SM, Walker CL.  April 2012

• Dissecting the Substrate Recognition of 3-O-sulfotransferase for the Biosynthesis of Anticoagulant Heparin  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22431632)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/5/dir/index.htm#a1)  Moon AF, Xu Y, Woody SM, Krahn JM, Linhardt RJ, Liu J, Pedersen LC.  April 2012

• Differential Estrogenic Actions of Endocrine-Disrupting Chemicals Bisphenol A, Bisphenol AF, and Zearalenone Through Estrogen Receptor Alpha and Beta In Vitro  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22494775)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/6/dir/index.htm#a3)  Li Y, Burns KA, Arao Y, Luh CJ, Korach KS.  April 2012

• Differential Effects of Poly(ADP-ribose) Polymerase Inhibition on DNA Break Repair in Human Cells Are Revealed with Epstein-Barr Virus  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22493268)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/6/dir/index.htm#a2)  Ma W, Halweg CJ, Menendez D, Resnick MA.  April 2012

• Association of Childhood Obesity with Maternal Exposure to Ambient Air Polycyclic Aromatic Hydrocarbons During Pregnancy  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22505764)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/6/dert/index.htm#a1)  Rundle A, Hoepner L, Hassoun A, Oberfield S, Freyer G, Holmes D, Reyes M, Quinn J, Camann D, Perera F, Whyatt R.  April 2012

• A Novel “Molecular Tweezer” Inhibitor of alpha-Synuclein Neurotoxity in Vitro and in Vivo  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22373667)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/5/dert/index.htm#a3)  Prabhudesai S, Sinha S, Attar A, Kotagiri A, Fitzmaurice AG, Lakshmanan R, Ivanova MI, Loo JA, Klärner FG, Schrader T, Stahl M, Bitan G, Bronstein JM.  April 2012

• Quantitative Microbial Risk Assessment of Human Illness from Exposure to Marine Beach Sand  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22296573)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/6/dert/index.htm#a3)  Shibata T, Solo-Gabriele HM.  March 2012

• Long-lived Epigenetic Interactions Between Perinatal PBDE Exposure and Mecp2308 Mutation  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22343140)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/4/dert/index.htm#a3)  Woods R, Vallero RO, Golub MS, Suarez JK, Ta TA, Yasui DH, Chi LH, Kostyniak PJ, Pessah IN, Berman RF, Lasalle JM.  March 2012

• Forecasting Sudden Changes in Environmental Pollution Patterns  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22411824)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/4/dert/index.htm#a2)  Olascoaga MJ, Haller G.  March 2012

• Calcium Influx-mediated Signaling is Required for Complete Mouse Egg Activation  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22371584)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/5/dir/index.htm#a2)  Miao YL, Stein P, Jefferson WN, Padilla-Banks E, Williams CJ.  March 2012

• Systemic SIRT1 Insufficiency Results in Disruption of Energy Homeostasis and Steroid Hormone Metabolism Upon High-Fat-Diet Feeding  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22006157)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/6/dir/index.htm#a4)  Purushotham A, Xu Q, Li X.  February 2012

• Fetal Exposure to Bisphenol A as a Risk Factor for the Development of Childhood Asthma: An Animal Model Study  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22353195)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/4/dert/index.htm#a4)  Nakajima Y, Goldblum RM, Midoro-Horiuti T.  February 2012

• Exposure to Particulate Air Pollution and Cognitive Decline in Older Women  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22332151)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/4/dert/index.htm#a1)  Weuve J, Puett RC, Schwartz J, Yanosky JD, Laden F, Grodstein F.  February 2012

• Single-nucleotide Base Excision Repair DNA Polymerase Activity in C. elegans in the Absence of DNA Polymerase Beta  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21917855)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/4/dir/index.htm#a2)  Asagoshi K, Lehmann W, Braithwaite EK, Santana-Santos L, Prasad R, Freedman JH, Van Houten B, Wilson SH.  January 2012

• Serum Vaccine Antibody Concentrations in Children Exposed to Perfluorinated Compounds  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22274686)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/2/extramural/index.htm#a2)  Grandjean P, Andersen EW, Budtz-Jorgensen E, Nielsen F, Molbak K, Weihe P, Heilmann C.  January 2012

• Rotenone Activates Phagocyte NADPH Oxidase by Binding to its Membrane Subunit gp91phox  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22094225)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/4/dir/index.htm#a1)  Zhou H, Zhang F, Chen SH, Zhang D, Wilson B, Hong JS, Gao HM.  January 2012

• Pulmonary CD103(+) Dendritic Cells Prime Th2 Responses to Inhaled Allergens  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22012243)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/3/dir/index.htm#a4)  Nakano H, Free ME, Whitehead GS, Maruoka S, Wilson RH, Nakano K, Cook DN.  January 2012

• Occurrence of Mental Illness Following Prenatal and Early Childhood Exposure to Tetrachloroethylene (PCE)-contaminated Drinking Water: A Retrospective Cohort Study  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22264316)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/3/dert/index.htm#a3)  Aschengrau A, Weinberg JM, Janulewicz PA, Romano ME, Gallagher LG, Winter MR, Martin BR, Vieira VM, Webster TF, White RF, Ozonoff DM.  January 2012

• Epoxyeicosanoids Stimulate Multiorgan Metastasis and Tumor Dormancy Escape in Mice  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22182838)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/3/dir/index.htm#a2)  [Newsletter Article] (http://www.niehs.nih.gov/news/newsletter/2012/1/science-cancer/index.htm)  Panigrahy D, Edin ML, Lee CR, Huang S, Bielenberg DR, Butterfield CE, Barnes CM, Mammoto A, Mammoto T, Luria A, Benny O, Chaponis DM, Dudley AC, Greene ER, Vergilio JA, Pietramaggiori G, Scherer-Pietramaggiori SS, Short SM, Seth M, Lih FB, Tomer KB, Yang J, Schwendener RA, Hammock BD, Falck JR, Manthati VL, Ingber DE, Kaipainen A, D’Amore PA, Kieran MW, Zeldin DC  January 2012

• Costs of Childhood Asthma Due to Traffic-related Pollution in Two California Communities  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22267764)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/3/dert/index.htm#a2)  Brandt SJ, Perez L, Künzli N, Lurmann F, McConnell R  January 2012

• Binary Complex Crystal Structure of DNA Polymerase Beta Reveals Multiple Conformations of the Templating 8-oxoguanine Lesion  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22178760)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/2/intramural/index.htm#a1)  Batra VK, Shock DD, Beard WA, McKenna CE, Wilson SH.  January 2012

• Associations Between Phthalate Metabolite Urinary Concentrations and Body Size Measure in New York City Children  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22222007)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/3/dert/index.htm#a1)  Teitelbaum SL, Mervish N, Moshier EL, Vangeepuram N, Galvez MP, Calafat AM, Silva MJ, Brenner BL, Wolff MS.  January 2012

• AHR2 Mutant Reveals Functional Diversity of Aryl Hydrocarbon Receptors in Zebrafish  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22242167)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/3/dert/index.htm#a4)  Goodale BC, La Du JK, Bisson WH, Janszen DB, Waters KM, Tanguay RL.  January 2012

• Rice Consumption Contributes to Arsenic Exposure in US Women  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22143778)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/1/dert/index.htm#a4)  Gilbert-Diamond D, Cottingham KL, Gruber JF, Punshon T, Sayarath V, Gandolfi AJ, Baker ER, Jackson BP, Folt CL, Karagas MR.  December 2011

• Quantitative Measurement of Airborne Cockroach Allergen in New York City Apartments  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21658130)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/2/extramural/index.htm#a4)  Esposito WA, Chew GL, Correa JC, Chillrud SN, Miller RL, Kinney PL.  December 2011

• Menthol Attenuates Respiratory Irritation Responses to Multiple Cigarette Smoke Irritants  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21903934)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/2/extramural/index.htm#a3)  [Newsletter Article] (http://www.niehs.nih.gov/news/newsletter/2011/october/science-menthol/index.cfm)  Willis DN, Liu B, Ha MA, Jordt SE, Morris JB.  December 2011

• Ligand-independent Phosphorylation of the Glucocorticoid Receptor Integrates Cellular Stress Pathways with Nuclear Receptor Signaling  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21930780)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/2/intramural/index.htm#a4)  Galliher-Beckley AJ, Williams JG, Cidlowski JA.  December 2011

• Estrogen Inhibits the Effects of Obesity and Alcohol on Mammary Tumors and Fatty Liver  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21850368)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/1/dert/index.htm#a3)  Hong J, Holcomb VB, Kushiro K, Núñez NP.  December 2011

• Early-life Soy Exposure and Gender-role Play Behavior in Children  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21813368)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/3/dir/index.htm#a3)  Adgent MA, Daniels JL, Edwards LJ, Siega-Riz AM, Rogan WJ.  December 2011

• Acute Depletion of Tet1-dependent 5-hydroxymethylcytosine Levels Impairs LIF/Stat3 Signaling and Results in Loss of Embryonic Stem Cell Identity  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22210859)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/3/dir/index.htm#a1)  Freudenberg JM, Ghosh S, Lackford BL, Yellaboina S, Zheng X, Li R, Cuddapah S, Wade PA, Hu G, Jothi R.  December 2011

• Urinary Mycoestrogens, Body Size and Breast Development in New Jersey Girls  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21975003)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/december/science-extramural/index.cfm#three)  Bandera EV, Chandran U, Buckley B, Lin Y, Isukapalli S, Marshall I, King M, Zarbl H.  November 2011

• Therapeutic Potential of Nrf2 Activators in Streptozotocin-induced Diabetic Nephropathy  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22025779)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/1/dert/index.htm#a2)  Zheng H, Whitman SA, Wu W, Wondrak GT, Wong PK, Fang D, Zhang DD.  November 2011

• Structural Basis for an Inositol Pyrophosphate Kinase Surmounting Phosphate Crowding  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22119861)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/2/intramural/index.htm#a3)  Wang H, Falck JR, Hall TM, Shears SB.  November 2011

• In Utero Exposure to Maternal Tobacco Smoke and Subsequent Obesity, Hypertension, and Gestational Diabetes Among Women in the MoBa Cohort  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22128036)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/2/intramural/index.htm#a2)  Cupul-Uicab LA, Skjaerven R, Haug K, Melve KK, Engel SM, Longnecker MP  November 2011

• Effect of Reduction in Household Air Pollution on Childhood Pneumonia in Guatemala (RESPIRE): A Randomised Controlled Trial  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22078686)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/december/science-extramural/index.cfm#one)  Smith KR, McCraken JP, Weber MW, Hubbard A, Jenny A, Thompson LM, Balmes J, Diaz A, Arana B, Bruce N.  November 2011

• Early-Life Exposures and Early Onset Uterine Leiomyomata in Black Women in the Sister Study   [Abstract] (http://ehp03.niehs.nih.gov/article/info%3Adoi%2F10.1289%2Fehp.1103620)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/1/dir/index.htm#a2)  D’Aloisio AA, Baird DD, DeRoo LA, Sandler DP.  November 2011

• Cyclic Electrowinning/Precipitation (CEP) System for the Removal of Heavy Metal Mixtures from Aqueous Solutions  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22102792)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/2/extramural/index.htm#a1)  Grimshaw P, Calo JM, Hradil G.  November 2011

• Canned Soup Consumption and Urinary Bisphenol A: A Randomized Crossover Trial  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22110104)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/1/dert/index.htm#a1)  Carwile JL, Ye X, Zhou X, Calafat AM, Michels KB.  November 2011

• Caffeine-induced Synaptic Potentiation in Hippocampal CA2 Neurons  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22101644)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/1/dir/index.htm#a1)  Simons SB, Caruana DA, Zhao M, Dudek SM.  November 2011

• Apolipoprotein E Genotypes and the Risk of Parkinson Disease  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21741729)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/december/science-intramural/index.cfm#one)  Gao J, Huang X, Park Y, Liu R, Hollenbeck A, Schatzkin A, Mailman RB, Chen H.  November 2011

• Whole Blueberry Powder Modulates the Growth and Metastasis of MDA-MB-231 Triple Negative Breast Tumors in Nude Mice  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21880954)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/december/science-extramural/index.cfm#two)  Adams LS, Kanaya N, Phung S, Liu Z, Chen S.  October 2011

• The Transcription Factors Snail an Slug Activate the Transforming Growth Factor-Beta Signaling Pathway in Breast Cancer  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/22028892)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/1/dir/index.htm#a4)  Dhasarathy A, Phadke D, Mav D, Shah RR, Wade PA.  October 2011

• The Impact of Menu Labeling on Fast-Food Purchases for Children and Parents  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21961472)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/december/science-extramural/index.cfm#four)  Tandon PS, Zhou C, Chan NL Lozano P, Couch SC, Glanz K, Krieger J, Saelens BE.  October 2011

• Structure of an Aprataxin-DNA Complex with Insights into AOA1 Neurodegenerative Disease  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21984210)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/december/science-intramural/index.cfm#three)  Tumbale P, Appel CD, Kraehenbuehl R, Roberson PD, Williams JS, Krahn J, Ahel I, Williams RS.  October 2011

• Liganded Pregnane X Receptor Represses the Human Sulfotransferase SULT1E1 Promoter Through Disrupting its Chromatin Structure  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21764778)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2012/1/dir/index.htm#a3)  Kodama S, Hosseinpour F, Goldstein JA, Negishi M.  October 2011

• Endothelial Expression of Human Cytochrome P450 Epoxygenase CYP2C8 Increases Susceptibility to Ischemia-Reperfusion Injury in Isolated Mouse Heart  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21697548)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/december/science-intramural/index.cfm#two)  Edin ML, Wang Z, Bradbury JA, Graves JP, Lih FB, DeGraff LM, Foley JF, Torphy R, Ronnekleiv OK, Tomer KB, Lee CR, Zeldin DC.  October 2011

• coMOTIF: A Mixture Framework for Identifying Transcription Factor and a Coregulator Motif in ChIP-seq Data  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21775309)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/december/science-intramural/index.cfm#four)  Xu M, Weinberg CR, Umbach DM, Li L.  October 2011

• Arsenic Migration to Deep Groundwater in Bangladesh Influence by Adsorption and Water Demand  [Abstract] (http://www.nature.com/ngeo/journal/v4/n11/abs/ngeo1283.html)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/november/science-extramural/index.cfm#one)  Radloff KA, Zheng Y, Michael HA, Stute M, Bostick BC, Mihajlov I, Bounds M, Huq MR, Choudhury I, Rahman MW, Schlosser P, Ahmed KM, van Green A.  October 2011

• A Dopamine Receptor (DRD2) But Not Dopamine Transporter (DAT1) Gene Polymorphism is Associated With Neurocognitive Development of Mexican Preschool Children With Lead Exposure  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21592505)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/november/science-extramural/index.cfm#four)  Kordas D, Ettinger AS, Bellinger DC, Schnaas L, Téllez Rojo MM, Hernández-Avila M, Hu H, Wright RO.  October 2011

• TP53 Mutational Signature for Aristolochic Acid: An Environmental Carcinogen  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21413016)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/november/science-extramural/index.cfm#two)  Moriya M, Slade N, Brdar B, Medverec Z, Tomic K, Jelaković B, Wu L, Truong S, Fernandes A, Grollman AP.  September 2011

• Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21778364)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/september/science-extramural/index.cfm#one)  Ito S, Shen L, Dai Q, Wu SC, Collins LB, Swenberg JA, He C, Zhang Y.  September 2011

• Novel Rank-based Approaches for Discovery and Replication in Genome-wide Association Studies  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21705758)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/november/science-intramural/index.cfm#three)  Kuo CL, Zaykin DV.  September 2011

• Induction of Regulatory T Cells by Green Tea Polyphenol EGCG  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21621552)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/november/science-extramural/index.cfm#three)  Wong CP, Nguyen LP, Noh SK, Bray TM, Bruno RS, Ho E.  September 2011

• IL-35 Production by Inducible Costimulator (ICOS)-postive Regulatory T Cells Reverses Established IL-17-dependent Allergic Airways Disease  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21906794)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/november/science-intramural/index.cfm#two)  Whitehead GS, Wilson RH, Nakano K, Burch LH, Nakano H, Cook DN.  September 2011

• Estrogen Receptor Alpha AF-2 Mutation Results in Antagonist Reversal and Reveals Tissue Selective Function of Estrogen Receptor Modulators  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21873215)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/november/science-intramural/index.cfm#one)  Arao Y, Hamilton KJ, Ray MK, Scott G, Mishina Y, Korach KS.  September 2011

• Cell Entry of One-Dimensional Nanomaterials Occurs by Tip Recognition and Rotation  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21926979)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/october/science-extramural/index.cfm#one)  Shi X, von dem Bussche A, Hurt RH, Kane AB, Gao H.  September 2011

• Permanent Oviduct Posteriorization Following Neonatal Exposure to the Phytoestrogen Genistein  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21810550)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/october/science-intramural/index.cfm#one)  Jefferson WN, Padilla-Banks E, Phelps JY, Gerrish JE, Williams CJ.  August 2011

• Identification of Candidate Genes Downstream of TLR4 Signaling After Ozone Exposure in Mice: A Role for Heat-Shock Protein 70.  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21543283)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/november/science-intramural/index.cfm#four)  Bauer AK, Rondini EA, Hummel KA, Degraff LM, Walker C, Jedlicka AE, Kleeberger SR.  August 2011

• High Environmental Relative Moldiness Index During Infancy as a Predictor of Asthma at 7 Years of Age  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21802019)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/october/science-extramural/index.cfm#four)  Reponen T, Vesper S, Levin L, Johansson E, Ryan P, Burkle J, Grinshpun SA, Zheng S, Bernstein DI, Lockey J, Villareal M, Khurana Hershey GK, LeMasters G.  August 2011

• Direct Reprogramming of Adult Human Fibroblasts to Functional Neurons Under Defined Conditions  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21802386)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/october/science-extramural/index.cfm#three)  Ambasudhan R, Talantova M, Coleman R, Yuan X, Zhu S, Lipton SA, Ding S.  August 2011

• Widespread RNA and DNA Sequence Differences in the Human Transcriptome  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21596952)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/october/science-extramural/index.cfm#two)  Li M, Wang IX, Li Y, Bruzel A, Richards AL, Toung JM, Cheung VG.  July 2011

• Timing-Dependent Septal Cholinergic Induction of Dynamic Hippocampal Synaptic Plasticity  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21745645)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/august/science-investigators/index.cfm)  Gu Z, Yakel JL.  July 2011

• The Landscape of Recombination in African Americans  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21775986)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/september/science-extramural/index.cfm#four)  Hinch AG, et al.  July 2011

• Proteomic Profiling of S-Acylated Macrophage Proteins Identifies a Role for Palmitoylation in Mitochondrial Targeting of Phospholipid Scramblase 3  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21785166)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/october/science-intramural/index.cfm#three)  Merrick BA, Dhungana S, Williams JG, Aloor JJ, Peddada S, Tomer KB, Fessler MB.  July 2011

• Prenatal Vitamins, One-Carbon Metabolism Gene Variants, and Risk for Autism  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21610500)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/september/science-extramural/index.cfm#two)  Schmidt RJ, Hansen RL, Hartiala J, Allayee H, Schmidt LC, Tancredi DJ, Tassone F, Hertz-Picciotto I.  July 2011

• Increased Efficacy of Doxorubicin Delivered in Multifunctional Microparticles for Mesothelioma Therapy  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20830711)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/september/science-extramural/index.cfm#three)  Hillegass JM, Blumen SR, Cheng K, MacPherson MB, Alexeeva V, Lathrop SA, Beuschel SL, Steinbacher JL, Butnor KJ, Ramos-Niño ME, Shukla A, James TA, Weiss DJ, Taatjes DJ, Pass HI, Carbone M, Landry CC, Mossman BT.  July 2011

• Efficiently Identifying Genome-wide Changes with Next-Generation Sequencing Data  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21803788)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/october/science-intramural/index.cfm#two)  Huang W, Umbach DM, Vincent Jordan N, Abell AN, Johnson GL, Li L.  July 2011

• Cyclooxygenase-2 Regulates Th17 Cell Differentiation During Allergic Lung Inflammation  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21474648)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/october/science-intramural/index.cfm#four)  Li H, Bradbury JA, Dackor RT, Edin ML, Graves JP, DeGraff LM, Wang PM, Bortner CD, Maruoka S, Lih FB, Cook DN, Tomer KB, Jetten AM, Zeldin DC.  July 2011

• Caffeine Promotes Ultraviolet B-induced Apoptosis in Human Keratinocytes without Complete DNA Repair  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21561856)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/august/science-extramural/index.cfm#three)  Han W, Ming M, He YY.  July 2011

• Assessment of Bisphenol A Released from Reusable Plastic, Aluminium and Stainless Steel Water Bottles  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21741673)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/august/science-extramural/index.cfm#one)  Cooper JE, Kendig EL, Belcher SM.  July 2011

• The Prostaglandin E2 Receptor, EP2, Regulates Survivin Expression via an EGFR/STAT3 Pathway in UVB-exposed Mouse Skin  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21268125)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/august/science-intramural/index.cfm#four)  Chun KS, Langenbach R.  June 2011

• Prostate Cancer and Ambient Pesticide Exposure in Agriculturally Intensive Areas in California  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21447478)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/august/science-extramural/index.cfm#four)  Cockburn M, Mills P, Zhang X, Zadnick J, Goldberg D, Ritz B.  June 2011

• Neuroinflammation and α-Synuclein Dysfunction Potentiate Each Other, Driving Chronic Progression of Neurodegeneration in a Mouse Model of Parkinson's Disease  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21245015)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/september/science-intramural/index.cfm#one)  Gao HM, Zhang F, Zhou H, Kam W, Wilson B, Hong JS.  June 2011

• Genome-wide Association Study of Prostate Cancer in Men of African Ancestry Identifies a Susceptibility Locus at 17q21  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21602798)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/august/science-extramural/index.cfm#two)  Haiman CA et al.  June 2011

• Garlic Extract Diallyl Sulfide (DAS) Activates Nuclear Receptor CAR to Induce the Sult1e1 Gene in Mouse Liver  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21698271)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/september/science-intramural/index.cfm#three)  Sueyoshi T, Green WD, Vinal K, Woodrum TS, Moore R, Negishi M.  June 2011

• Expanded Methyl-sensitive Cut Counting Reveals Hypomethylation as an Epigenetic State that Highlights Functional Sequences of the Genome  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21602498)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/august/science-intramural/index.cfm#three)  Colaneri A, Staffa N, Fargo DC, Gao Y, Wang T, Peddada SD, Birnbaumer L.  June 2011

• Cadmium Induces Transcription Independently of Intracellular Calcium Mobilization  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21694771)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/september/science-intramural/index.cfm#two)  Tvermoes BE, Bird GS, Freedman JH.  June 2011

• Reactive Nanostructured Membranes for Water Purification  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21606340)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/june/science-extramural/index.cfm#one)  Lewis SR, Datta S, Gui M, Coker EL, Huggins FE, Daunert S, Bachas L, Bhattacharyya D.  May 2011

• Rapid Activity-induced Transcription of Arc and Other IEGs Relies on Poised RNA Polymerase II  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21623364)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/august/science-intramural/index.cfm#two)  Saha RN, Wissink EM, Bailey ER, Zhao M, Fargo DC, Hwang JY, Daigle KR, Fenn JD, Adelman K, Dudek SM.  May 2011

• Mechanical Stretch Induces Epithelial-Mesenchymal Transition in Alveolar Epithelia via Hyaluronan Activation of Innate Immunity  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21398522)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/august/science-intramural/index.cfm#one)  Heise RL, Stober V, Cheluvaraju C, Hollingsworth JW, Garantziotis S.  May 2011

• Comparative Study on the Response of Rat Primary Astrocytes and Microglia to Methylmercury Toxicity  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21351162)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/july/science-extramural/index.cfm#four)  Ni M, Li X, Yin Z, Sidoryk-Wegrzynowicz M, Jiang H, Farina M, Rocha JB, Syversen T, Aschner M.  May 2011

• Aberrant Lipid Metabolism Disrupts Calcium Homeostasis Causing Liver Endoplasmic Reticulum Stress in Obesity  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21532591)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/july/science-extramural/index.cfm#three)  Fu S, Yang L, Li P, Hofmann O, Dicker L, Hide W, Lin X, Watkins SM, Ivanov AR, Hotamisligil GS.  May 2011

• Structural Insights into Catalytic and Substrate Binding Mechanisms of the Strategic EndA Nuclease from Streptococcus pneumoniae  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21113026)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/july/science-intramural/index.cfm#three)  Moon AF, Midon M, Meiss G, Pingoud A, London RE, Perdersen LC.  April 2011

• Selective Mutations in Estrogen Receptor Alpha D-domain Alters Nuclear Translocation and Non-estrogen Response Element Gene Regulatory Mechanisms  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21285458)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/june/science-intramural/index.cfm#three)  Burns KA, Li Y, Arao Y, Petrovich RM, Korach KS.  April 2011

• Regular Breakfast and Blood Lead Levels Among Preschool Children  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21457535)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/july/science-extramural/index.cfm#two)  Liu J, McCauley L, Compher C, Yan C, Shen X, Needleman H, Pinto-Martin JA.  April 2011

• PAH/Aromatic DNA Adducts in Cord Blood and Behavior Scores in New York City Children  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21486719)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/july/science-extramural/index.cfm#one)  Perera FP, Wang S, Vishnevetsky J, Zhang B, Cole KJ, Tang D, Rauh V, Phillips DH.  April 2011

• Inhibition of Fried Meat-induced Colorectal DNA Damage and Altered Systemic Genotoxicity in Humans by Crucifera, Chlorophyllin, and Yogurt  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21541030)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/july/science-intramural/index.cfm#one)  Shaughnessy DT, Gangarosa LM, Schliebe B, Umbach DM, Xu Z, MacIntosh B, Knize MG, Matthews PP, Swank AE, Sandler RS, DeMarini DM, Taylor JA.  April 2011

• Beta2-adrenergic Receptor Activation Prevents Rodent Dopaminergic Neurotoxicity by Inhibiting Microglia Via a Novel Signaling Pathway  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21335487)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/july/science-intramural/index.cfm#four)  Qian L, Wu HM, Chen SH, Zhang D, Ali SF, Peterson L, Wilson B, Lu RB, Hong JS, Flood PM.  April 2011

• Aryl Hydrocarbon Receptor Activation During Pregnancy, and in Adult Nulliparous Mice, Delays the Subsequent Development of DMBA-induced Mammary tumors  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20521247)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/june/science-extramural/index.cfm#three)  Wang T, Gavin HM, Arlt VM, Lawrence BP, Fenton SE, Medina D, Vorderstrasse BA.  April 2011

• Amyloid-binding Compounds Maintain Protein Homeostasis During Ageing and Extend Lifespan  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21451522)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/may/science-extramural/index.cfm#two)  Alavez S, Vantipalli MC, Zucker DJ, Klang IM, Lithgow GJ.  April 2011

• Alkylation Base Damage is Converted into Repairable Double-strand Breaks and Complex Intermediates in G2 Lacking AP Endonuclease  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21552545)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/july/science-intramural/index.cfm#two)  Ma W, Westmoreland JW, Gordenin DA, Resnick MA.  April 2011

• A Comparison of PBDE Serum Concentrations in Mexican and Mexican-American Children Living in California  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21498147)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/june/science-extramural/index.cfm#two)  Eskenazi B, Fenster L, Castorina R, Marks AR, Sjödin A, Rosas LG, Holland N, Guerra AG, López-Carrillo L, Bradman A.  April 2011

• The Toll-like Receptor Gene Family Is Integrated into Human DNA Damage and p53 Networks  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21483755)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/june/science-intramural/index.cfm#one)  Menendez D*, Shatz M*, Azzam K, Garantziotis S, Fessler MB, Resnick MA. (*co-first authors)  March 2011

• Mercury Exposure and Risk of Cardiovascular Disease in Two U.S. Cohorts  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21428767)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/may/science-extramural/index.cfm#three)  Mozaffarian D, Shi P, Morris JS, Spiegelman D, Grandjean P, Siscovick DS, Willet WC, Rimm EB.  March 2011

• Hotspots of Aberrant Epigenetic Reprogramming in Human Induced Pluripotent Stem Cells  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21289626)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/april/science-extramural/index.cfm#two)  Lister R, Pelizzola M, Kida YS, Hawkins RD, Nery JR, Hon G, Antosiewicz-Bourget J, O'Malley R, Castanon R, Klugman S, Downes M, Yu R, Stewart R, Ren B, Thomson JA, Evans RM, Ecker JR.  March 2011

• Crucial Role for DNA Ligase III in Mitochondria But Not in Xrcc1-dependent Repair  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21390132)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/may/science-extramural/index.cfm#four)  Simsek D, Furda A, Gao Y, Artus J, Brunet E, Hadjantonakis AK, Van Houten B, Shuman S, McKinnon PJ, Jasin M.  March 2011

• Alternate Modes of Cognate RNA Recognition by Human PUMILIO Proteins  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21397187)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/june/science-intramural/index.cfm#two)  Lu G, Hall TM.  March 2011

• Resveratrol (3,5,4'-trihydroxystilbene) Protects Pregnant Mother and Fetus from the Immunotoxic Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20715097)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/april/science-extramural/index.cfm#one)  Singh NP, Singh US, Nagarkatti M, Nagarkatti PS.  February 2011

• Replication Infidelity via a Mismatch with Watson-Crick Geometry  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21233421)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/march/science-intramural/#three)  [Story] (http://www.niehs.nih.gov/news/newsletter/2011/february/science-mismatch/index.cfm)  Bebenek K, Pedersen LC, Kunkel TA.  February 2011

• Med25 Is Required for RNA Polymerase II Recruitment To Specific Promoters, Thus Regulating Xenobiotic and Lipid Metabolism In Human Liver  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21135126)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/may/science-intramural/index.cfm#four)  Rana R, Surapureddi S, Kam W, Ferguson S, Goldstein JA.  February 2011

• Mechanistic Basis of Resistance to PCBs in Atlantic Tomcod from the Hudson River  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21330491)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/march/science-extramural/#one)  Wirgin I, Roy NK, Loftus M, Chambers RC, Franks DG, Hahn ME.  February 2011

• Evidence from Chile That Arsenic in Drinking Water May Increase Mortality from Pulmonary Tuberculosis  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21190988)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/april/science-extramural/index.cfm#three)  Smith AH, Marshall G, Yuan Y, Liaw J, Ferreccio C, Steinmaus C.  February 2011

• Estimated Reduction in Cancer Risk Due to PAH Exposures if Source Control Measures During the 2008 Beijing Olympics Were Sustained  [Abstract] (http://ehp03.niehs.nih.gov/article/fetchArticle.action?articleURI=info%3Adoi%2F10.1289%2Fehp.1003100)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/may/science-extramural/index.cfm#one)  Jia Y, Stone D, Wang W, Schrlau J, Tao S, Massey Simonich SL.  February 2011

• Environmental Tobacco Smoke Furthers Progression of Diabetic Nephropathy  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20924282)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/april/science-extramural/index.cfm#four)  Obert DM, Hua P, Pilkerton ME, Feng W, Jaimes EA.  February 2011

• Aryl Hydrocarbon Receptor-mediated Up-regulation of ATP-driven Xenobiotic Efflux Transporters at the Blood-Brain Barrier  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21048045)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/may/science-intramural/index.cfm#two)  Wang X, Hawkins BT, Miller DS.  February 2011

• Nuclear Orphan Receptor TAK1/TR4-deficient Mice Are Protected Against Obesity-linked Inflammation, Hepatic Steatosis, and Insulin Resistance  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20864514)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/april/science-intramural-papers/index.cfm#three)  Kang HS, Okamoto K, Kim YS, Takeda Y, Bortner CD, Dang H, Wada T, Xie W, Yang XP, Liao G, Jetten AM.  January 2011

• Mortality in the Agricultural Health Study, 1993-2007  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21084556)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/april/science-intramural-papers/index.cfm#four)  Waggoner JK, Kullman GJ, Henneberger PK, Umbach DM, Blair A, Alavanja MC, Kamel F, Lynch CF, Knott C, London SJ, Hines CJ, Thomas KW, Sandler DP, Lubin JH, Beane Freeman LE, Hoppin JA.  January 2011

• Interactions of Lifetime Lead Exposure and Stress: Behavioral, Neurochemical and HPA Axis Effects  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20875452)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/march/science-extramural/#four)  Rossi-George A, Virgolini MB, Weston D, Thiruchelvam M, Cory-Slechta DA.  January 2011

• Human Single-nucleotide Polymorphisms Alter p53 Sequence-specific Binding at Gene Regulatory Elements  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20817676)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/april/science-intramural-papers/index.cfm#one)  Bandele OJ, Wang X, Campbell MR, Pittman GS, Bell DA.  January 2011

• HMGB1 Acts on Microglia Mac1 to Mediate Chronic Neuroinflammation That Drives Progressive Neurodegeneration  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21248133)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/march/science-intramural/#one)  Gao HM, Zhou H, Zhang F, Wilson BC, Kam W, Hong JS.  January 2011

• Genetic Variation in the Glutathione Synthesis Pathway, Air Pollution, and Children's Lung Function Growth  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20802163)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/march/science-extramural/#three)  Breton CV, Salam MT, Vora H, Gauderman WJ, Gilliland FD.  January 2011

• Estrogenic Activity of Bisphenol A and 2,2-bis(p-hydroxyphenyl)-1,1,1-trichloroethane (HPTE) Demonstrated in Mouse Uterine Gene Profiles  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20826375)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/may/science-intramural/index.cfm#three)  Hewitt SC, Korach KS.  January 2011

• Elevated Plasma Cytokines in Autism Spectrum Disorders Provide Evidence of Immune Dysfunction and Are Associated with Impaired Behavioral Outcome  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20705131)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/march/science-extramural/#two)  Ashwood P, Krakowiak P, Hertz-Picciotto I, Hansen R, Pessah I, Van de Water J.  January 2011

• Deciphering the Clinical Presentations, Pathogenesis, and Treatment of the Idiopathic Inflammatory Myopathies  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21224460)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/march/science-intramural/#four)  [Story] (http://www.niehs.nih.gov/news/newsletter/2011/march/science-intramural/#four)  Rider LG, Miller FW.  January 2011

• Augmented Glucose-induced Insulin Release in Mice Lacking G(o2), But Not G(o1) or G(i) Proteins  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21220323)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/may/science-intramural/index.cfm#one)  Wang Y, Park S, Bajpayee NS, Nagaoka Y, Boulay G, Birnbaumer L, Jiang M.  January 2011

• Serum Unconjugated Bisphenol A Concentrations in Women May Adversely Influence Oocyte Quality During In Vitro Fertilization  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21122836)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/january/science-extramural.cfm#one)  Fujimoto VY, Kim D, Vom Saal FS, Lamb JD, Taylor JA, Bloom MS.  December 2010

• Semen Quality and Sperm DNA Damage in Relation to Urinary Bisphenol A Among Men from an Infertility Clinic  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20656017)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/february/science-extramural/#four)  Meeker JD, Ehrlich S, Toth TL, Wright DL, Calafat AM, Trisini AT, Ye X, Hauser R.  December 2010

• Rewiring of Genetic Networks in Response to DNA Damage  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21127252)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/february/science-extramural/#two)  Bandyopadhyay S, Mehta M, Kuo D, Sung MK, Chuang R, Jaehnig EJ, Bodenmiller B, Licon K, Copeland W, Shales M, Fiedler D, Dutkowski J, Guénolé A, van Attikum H, Shotkat KM, Kolodner RD, Huh WK, Aebersold R, Keogh MC, Krogan NJ, Ideker T.  December 2010

• Reversal of a Mutator Activity by a Nearby Fidelity-neutral Substitution in the RB69 DNA Polymerase Binding Pocket  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20950625)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/april/science-intramural-papers/index.cfm#two)  Trzemecka A, Jacewicz A, Carver GT, Drake JW, Bebenek A.  December 2010

• Residential Proximity to Freeways and Autism in the CHARGE Study  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21156395)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/january/science-extramural.cfm#two)  Volk HE, Hertz-Picciotto I, Delwiche L, Lurmann F, McConnell R.  December 2010

• Protective Role of Interleukin-10 in Ozone-induced Pulmonary Inflammation  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20826374)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/march/science-intramural/#two)  Backus GS, Howden R, Fostel J, Bauer AK, Cho HY, Marzec J, Peden DB, Kleeberger SR.  December 2010

• Predicting the Hepatocarcinogenic Potential of Alkenylbenzene Flavoring Agents Using Toxicogenomics and Machine Learning  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20004213)   Auerbach SS, Shah RR, Mav D, Smith CS, Walker NJ, Vallant MK, Boorman GA, Irwin RD.  December 2010

• Mitochondrial Dysfunction in Autism  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21119085)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/february/science-extramural/#one)  Giulivi C, Zhang YF, Omanska-Klusek A, Ross-Inta C, Wong S, Hertz-Picciotto I, Tassone F, Pessah IN.  December 2010

• Lysine 63-linked Ubiquitination is Important for Arachidonic Acid-induced Cellular Adhesion and Migration  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21102657)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/february/science-intramural/#two)  Ray DM, Rogers BA, Sunman JA, Akiyama SK, Olden K, Roberts JD.  December 2010

• Distribution and Clearance of PEG-single-walled Carbon Nanotube Cancer Drug Delivery Vehicles in Mice  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21143032)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/february/science-extramural/#three)  Bhirde AA, Patel S, Sousa AA, Patel V, Molinolo AA, Ji Y, Leapman RD, Gutkind JS, Rushling JF.  December 2010

• Uterine Epithelial Estrogen Receptor Alpha Is Dispensable For Proliferation but Essential for Complete Biological and Biochemical Responses  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20974921)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/january/science-intramural.cfm#two)  Winuthayanon W, Hewitt SC, Orvis GD, Behringer RR, Korach KS.  November 2010

• Ubiquitin-dependent and Ubiquitin-independent Control of Subunit Stoichiometry in the SWI/SNF Complex  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20829358)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/february/science-intramural/#three)  Keppler BR, Archer TK.  November 2010

• Rapid Desensitization of the Rat 7 nAChR is Facilitated by the Presence of a Proline Residue in the Outer Beta-sheet  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20837638)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/february/science-intramural/#four)  McCormack TJ, Melis C, Colón J, Gay EA, Mike A, Karoly R, Lamb PW, Molteni C, Yakel JL.  November 2010

• Pausing of RNA Polymerase II Disrupts DNA-specified Nucleosome Organization To Enable Precise Gene Regulation  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21074046)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/january/science-intramural.cfm#one)  Gilchrist DA, Dos Santos G, Fargo DC, Xie B, Gao Y, Li L, Adelman K.  November 2010

• Ischemic Heart Disease and Stroke in Relation To Blood DNA Methylation  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20805753)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/january/science-extramural.cfm#four)  Baccarelli A, Wright R, Bollati V, Litonjua A, Zanobetti A, Tarantini L, Sparrow D, Vokonas P, Schwartz J.  November 2010

• Heatwaves in the United States: Mortality Risk During Heatwaves and Effect Modification by Heatwave Characteristics in 43 U.S. Communities  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/21084239)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/december/science-extramural.cfm#one)  Anderson GB, Bell ML.  November 2010

• Glucocorticoids Modulate MicroRNA Expression and Processing During Lymphocyte Apoptosis  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20847043)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/february/science-intramural/#one)  Smith LK, Shah RR, Cidlowski JA.  November 2010

• A Colorimetric Sensor Array for Detection of Triacetone Triperoxide Vapor  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20949933)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/january/science-extramural.cfm#three)  Lin H, Suslick KS.  November 2010

• Sexually Dimorphic Actions of Glucocorticoids Provide a Link to Inflammatory Diseases With Gender Differences in Prevalence  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20940427)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/december/science-intramural.cfm#four)  Duma D, Collins JB, Chou JW, Cidlowski JA.  October 2010

• Genome-wide Model for the Normal Eukaryotic DNA Replication Fork  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20876092)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/january/science-intramural.cfm#four)  Larrea AA, Lujan SA, Nick McElhinny SA, Mieczkowski PA, Resnick MA, Gordenin DA, Kunkel TA.  October 2010

• Epigenetic Influences of Low-dose Bisphenol A in Primary Human Breast Epithelial Cells  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20678512)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/december/science-extramural.cfm#three)  Weng YI, Hsu PY, Liyanarachchi S, Liu J, Deatherage DE, Huang YW, et al.  October 2010

• Environment and Disease Risks  [Abstract] (http://www.sciencemag.org/content/330/6003/460.summary)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/december/science-extramural.cfm#two)  Rappaport SM, Smith MT.  October 2010

• Endothelial Expression of Human Cytochrome P450 Epoxygenases Lowers Blood Pressure and Attenuates Hypertension-induced Renal Injury in Mice  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20495177)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2011/january/science-intramural.cfm#three)  Lee CR, Imig JD, Edin ML, Foley J, DeGraff LM, Bradbury JA, Graves JP, Lih FB, Clark J, Myers P, Perrow AL, Lepp AN, Kannon MA, Ronnekleiv OK, Alkayed NJ, Falck JR, Tomer KB, Zeldin DC.  October 2010

• Efficacy of Succimer Chelation of Mercury at Background Exposures in Toddlers: A Randomized Trial  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20889164)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/december/science-intramural.cfm#one)  Cao Y, Chen A, Jones RL, Radcliffe J, Dietrich KN, Caldwell KL, et al.  October 2010

• Complement-mediated Regulation of the IL-17A Axis Is a Central Genetic Determinant of the Severity of Experimental Allergic Asthma  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20802484)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/december/science-extramural.cfm#four)  Lajoie S, Lewkowich IP, Suzuki Y, Clark JR, Sproles AA, Dienger K, et al.  October 2010

• RGS14 Is a Natural Suppressor of Both Synaptic Plasticity in CA2 Neurons and Hippocampal-based Learning and Memory  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20837545)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/december/science-intramural.cfm#two)  Lee SE, Simons SB, Heldt SA, Zhao M, Schroeder JP, Vellano CP, et al.  September 2010

• Prenatal Exposure to Airborne Polycyclic Aromatic Hydrocarbons and Children's Intelligence at Age 5 in a Prospective Cohort Study in Poland  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20406721)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/november/science-extramural.cfm#four)  Edwards SC, Jedrychowski W, Butscher M, Camann D, Kieltyka A, Mroz E, et al.  September 2010

• Mutagenesis Dependent Upon the Combination of Activation-induced Deaminase Expression and a Double-strand Break  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20828826)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/november/science-intramural.cfm#two)  Poltoratsky V, Heacock M, Kissling GE, Prasad R, Wilson SH.  September 2010

• Metabolic Profiling of Murine Plasma Reveals an Unexpected Biomarker in Rofecoxib-mediated Cardiovascular Events  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20837537)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/november/science-extramural.cfm#one)  Liu JY, Li N, Yang J, Li N, Qiu H, Ai D, et al.  September 2010

• Inhibitors of Leucine-rich Repeat Kinase-2 Protect Against Models of Parkinson's Disease  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20729864)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/november/science-extramural.cfm#three)  Lee BD, Shin JH, VanKampen J, Petrucelli L, West AB, Ko HS, et al.  September 2010

• Genome Instability Due to Ribonucleotide Incorporation into DNA  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20729855)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/november/science-intramural.cfm#three)  Nick McElhinny SA, Kumar D, Clark AB, Watt DL, Watts BE, Lundström EB, et al.  September 2010

• Disease Variants of the Human Mitochondrial DNA Helicase Encoded by C10orf2 Differentially Alter Protein Stability, Nucleotide Hydrolysis, and Helicase Activity  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20659899)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/december/science-intramural.cfm#three)  Longley MJ, Humble MM, Sharief FS, Copeland WC.  September 2010

• Aryl Hydrocarbon Receptor Antagonists Promote the Expansion of Human Hematopoietic Stem Cells  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20688981)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/october/science-extramural.cfm#one)  Boitano AE, Wang J, Romeo R, Bouchez LC, Parker AE, Sutton SE, et al.  September 2010

• A Large-scale, Consortium-based Genomewide Association Study of Asthma  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20860503)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/november/science-extramural.cfm#two)  Moffatt MF, Gut IG, Demenais F, Strachan DP, Bouzigon E, Heath S, et al.  September 2010

• The Effect of Light Rail Transit on Body Mass Index and Physical Activity  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20621257)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/october/science-extramural.cfm#four)  MacDonald JM, Stokes RJ, Cohen DA, Kofner A, Ridgeway GK.  August 2010

• Genetic Variation and Antioxidant Response Gene Expression in the Bronchial Airway Epithelium of Smokers at Risk for Lung Cancer  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20689807)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/october/science-intramural.cfm##three)  Wang X, Chorley BN, Pittman GS, Kleeberger SR, Brothers J 2nd, Liu G, et al.  August 2010

• Gene Expression in the Fetal Mouse Ovary Is Altered by Exposure to Low Doses of Bisphenol A  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20739668)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/october/science-extramural.cfm#two)  Lawson C, Gieske M, Murdoch B, Ye P, Li Y, Hassold T, Hunt PA.  August 2010

• Estrogen Receptor Beta Signaling Through Phosphatase and Tensin Homolog/Phosphoinositide 3-Kinase/Akt/Glycogen Synthase Kinase 3 Down-Regulates Blood-Brain Barrier Breast Cancer Resistance Protein  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20460386)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/october/science-intramural.cfm#one)  Hartz AM, Madole EK, Miller DS, Bauer B.  August 2010

• Dyslipidemia Induces Opposing Effects on Intrapulmonary and Extrapulmonary Host Defense Through Divergent TLR Response Phenotypes  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20581153)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/september/science-intramural.cfm#two)  Madenspacher JH, Draper DW, Smoak KA, Li H, Griffiths GL, Suratt BT, et al.  August 2010

• DNA Methylation Prevents CTCF-mediated Silencing of the Oncogene BCL6 in B Cell Lymphomas  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20733034)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/november/science-intramural.cfm#four)  Lai AY, Fatemi M, Dhasarathy A, Malone C, Sobol SE, Geigerman C, et al.  August 2010

• Der p 5 Crystal Structure Provides Insight Into the Group 5 Dust Mite Allergens  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20534590)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/november/science-intramural.cfm#one)  Mueller GA, Gosavi RA, Krahn JM, Edwards LL, Cuneo MJ, Glesner L, et al.  August 2010

• Biological, Clinical and Population Relevance of 95 Loci for Blood Lipids  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20686565)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/october/science-extramural.cfm##three)  Teslovich TM, Musunuru K, Smith AV, Edmondson AC, Stylianou IM, Koseki M, et al.  August 2010

• A Single-Strand Specific Lesion Drives MMS-Induced Hyper-Mutability at a Double-Strand Break in Yeast  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20663718)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/october/science-intramural.cfm#two)  Yang Y, Gordenin DA, Resnick MA.  August 2010

• Protein Radical Formation Resulting from Eosinophil Peroxidase-Catalyzed Oxidation of Sulfite  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20501663)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/october/science-intramural.cfm#four)  Ranguelova K, Chatterjee S, Ehrenshaft M, Ramirez DC, Summers FA, Kadiiska MB, Mason RP.  July 2010

• Myeloid Deletion of SIRT1 Induces Inflammatory Signaling in Response to Environmental Stress  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20647536)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/september/science-intramural.cfm#one)  Schug TT, Xu Q, Gao H, Peres-da-Silva A, Draper DW, Fessler MB, et al.  July 2010

• Mutagenic Conformation of 8-oxo-7,8-dihyro-2’-dGTP in the Confines of a DNA Polymerase Active Site  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20526335)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/august/science-intramural.cfm#one)  Batra VK, Beard WA, Hou EW, Pedersen LC, Prasad R, Wilson SH.  July 2010

• Disruption of the Clock Components CLOCK and BMAL1 Leads to Hypoinsulinaemia and Diabetes  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20562852)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/september/science-extramural.cfm#two)  Marcheva B, Ramsey KM, Buhr ED, Kobayashi Y, Su H, Ko CH, et al.  July 2010

• Cohesin is Limiting for the Suppression of DNA Damage-induced Recombination Between Homologous Chromosomes  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20617204)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/september/science-intramural.cfm#three)  Covo S, Westmoreland JW, Gordenin DA, Resnick MA.  July 2010

• Chronic Lung Disease in Preterm Lambs: Effect of Daily Vitamin A Treatment on Alveolarization  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20382748)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/september/science-extramural.cfm#four)  Albertine KH, Dahl MJ, Gonzales LW, Wang ZM, Metcalfe D, Hyde DM, et al.  July 2010

• Bisphenol-A Exposure In utero Leads to Epigenetic Alterations in the Developmental Programming of Uterine Estrogen Response  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20181937)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/september/science-extramural.cfm#three)  Bromer JG, Zhou Y, Taylor MB, Doherty L, Taylor HS.  July 2010

• (Bi)sulfite Oxidation by Copper, Zinc-superoxide Dismutase: Sulfite-derived, Radical-initiated Protein Radical Formation  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20348042)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/september/science-intramural.cfm#four)  Ranguelova K, Bonini MG, Mason RP.  July 2010

• Reconstituting Organ-level Lung Functions on a Chip  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20576885)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/august/science-extramural.cfm#two)  Huh D, Matthews BD, Mammoto A, Montoya-Zavala M, Hsin HY, Ingber DE.  June 2010

• Polybrominated Diphenylether (PBDE) Flame Retardants and Thyroid Hormone During Pregnancy  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20562054)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/july/science-extramural.cfm#two)  Chevrier J, Harley KG, Bradman A, Gharbi M, Sjödin A, Eskenazi B.  June 2010

• Myeloid Differentiation Primary Response Protein 88 Couples Reverse Cholesterol Transport to Inflammation  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20519121)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/august/science-intramural.cfm#two)  Smoak KA, Aloor JJ, Madenspacher J, Merrick BA, Co  June 2010

• Molecular Characterization of numr-1 and numr-2: Genes That Increase Both Resistance to Metal-induced Stress and Lifespan in Caenorhabditis elegans  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20501697)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/august/science-intramural.cfm##four)  Tvermoes BE, Boyd WA, Freedman JH.  June 2010

• Modulation of Allergic Airway Inflammation by the Oral Pathogen Porphyromonas gingivalis  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20308298)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/june/science-intramural.cfm#inside-two)  Card JW, Carey MA, Voltz JW, Bradbury JA, Ferguson CD, Cohen EA, et al.  June 2010

• Helix Unwinding and Base Flipping Enable Human MTERF1 to Terminate Mitochondrial Transcription  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20550934)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/august/science-extramural.cfm#three)  Yakubovskaya E, Mejia E, Byrnes J, Hambardjieva E, Gracia-Diaz M.  June 2010

• Exposure to Polyfluoroalkyl Chemicals and Attention Deficit Hyperactivity Disorder in U.S. Children Aged 12–15 Years  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20551004)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/september/science-extramural.cfm#one)  Hoffman K, Webster TF, Weisskopf MG, Weinberg J, Viera VM.  June 2010

• Associations of PM10 With Sleep and Sleep-disordered Breathing in Adults from Seven U.S. Urban Areas  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20508218)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/august/science-extramural.cfm#one)  Zanobetti A, Redline S, Schwartz J, Rosen D, Patel S, O’Connor GT, et al.  June 2010

• Arsenic Exposure from Drinking Water, and All-Cause and Chronic-disease Mortalities in Bangladesh (HEALS): A Prospective Cohort Study  [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/july/science-extramural.cfm#one)  Argos M, Kalra T, Rathouz PJ, Chen Y, Pierce B, Parvez F, et al.  June 2010

• Activin A, a Product of Fetal Leydig Cells, Is a Unique Paracrine Regulator of Sertoli Cell Proliferation and Fetal Testis Cord Expansion  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20498064)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/august/science-extramural.cfm#four)  Archambeault DR, Yao HH.  June 2010

• Spatial and Temporal Variation of Groundwater Arsenic in South and Southeast Asia  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20508123)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/july/science-extramural.cfm#three)  Fendorf S, Michael HA, van Geen A.  May 2010

• Regulation of ERR-alpha Gene Expression by Estrogen Receptor Agonists and Antagonists in SKBR3 Breast Cancer Cells: Differential Molecular Mechanisms Mediated by G Protein-Coupled Receptor GPR30/GPER1  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20211987)   Li Y, Birnbaumer L, Teng CT.  May 2010

• Ozone Activates Pulmonary Dendritic Cells and Promotes Allergic Sensitization Through a Toll-like Receptor 4-dependent Mechanism  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20394980)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/august/science-intramural.cfm#three)  Hollingsworth JW, Free ME, Li Z, Andrews LN, Nakano H, Cook DN.  May 2010

• Obligatory Role in GTP Hydrolysis for the Amide Carbonyl Oxygen of the Mg(2+)-coordinating Thr of Regulatory GTPases  [Abstract] (http://www.ncbi.nlm.nih.gov/sites/pubmed/20457940)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/july/science-intramural.cfm#one)  Zurita A, Zhang Y, Pedersen L, Darden T, Birnbaumer L.  May 2010

• Kidney Injury Molecule-1 Outperforms Traditional Biomarkers of Kidney Injury in Preclinical Biomarker Qualification Studies  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20458318)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/july/science-extramural.cfm#four)  Vaidya VS, Ozer JS, Dieterle F, Collings FB, Ramirez V, Troth S, et al.  May 2010

• Arsenic-specific Stem Cell Selection During Malignant Transformation  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20339138)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/july/science-intramural.cfm#four)  Tokar EJ, Qu W, Liu J, Liu W, Webber MM, Phang JM, Waalkes MP.  May 2010

• The Structure of the Dust Mite Allergen Der p 7 Reveals Similarities to Innate Immune Proteins  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20226507)   Mueller GA, Edwards LL, Aloor JJ, Fessler MB, Glesner J, Pomes A, et al.  April 2010

• Testing Haplotype-Environment Interactions Using Case-Parent Triads  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20413979)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/june/science-intramural.cfm#inside-four)  Shi M, Umbach DM, Weinberg CR.  April 2010

• Risk for Asthma in Offspring of Asthmatic Mothers Versus Fathers: a Meta-Analysis  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20405032)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/june/science-extramural.cfm#four)  Lim RH, Kobzik L, Dahl M.  April 2010

• Prenatal Phthalate Exposure and Reduced Masculine Play in Boys  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/19919614)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/june/science-extramural.cfm#three)  Swan SH, Liu F, Hines M, Kruse RL, Wang C, Redmon JB, et al.  April 2010

• Oxidation State of the XRCC1 N-Terminal Domain Regulates DNA Polymerase Beta Binding Affinity  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20351257)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/june/science-intramural.cfm#inside-three)  Cuneo MJ, London RE.  April 2010

• Nuclear Receptor CAR Represses TNFalpha-induced Cell Death by Interacting with the Anti-apoptotic GADD45B  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20404936)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/july/science-intramural.cfm#three)  Yamamoto Y, Moore R, Flavell RA, Lu B, Negishi M.  April 2010

• Fate of PCB congeners in an industrial harbor of Lake Michigan  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20131898?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1)   Martinez A, Wang K, Hornbuckle KC.  April 2010

• DYRK1A and DYRK3 Promote Cell Survival Through Phosphorylation and Activation of SIRT1  [Abstract] (http://www.ncbi.nlm.nih.gov/sites/pubmed/20167603)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/july/science-intramural.cfm#two)  Guo X, Williams JG, Schug TT, Li X.  April 2010

• Age-Dependent Decreases in DNA Methyltransferase Levels and Low Transmethylation Micronutrient Levels Synergize to Promote Overexpression of Genes Implicated in Autoimmunity and Acute Coronary Syndromes  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20035856)   [Synopsis] (http://www.niehs.nih.gov/news/newsletter/2010/june/science-extramural.cfm#two)  Li Y, Liu Y, Strickland FM, Richardson B.  April 2010

• Promotion of Variant Human Mammary Epithelial Cell Outgrowth by Ionizing Radiation: An Agent-Based Model Supported by In Vitro Studies. Breast Cancer Res.  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20146798)   Mukhopadhyay R, Costes SV, Bazarov AV, Hines WC, Barcellos-Hoff MH, Yaswen P.  February 2010

• Prenatal Acetaminophen Exposure and Risk of Wheeze at Age 5 Years in an Urban Low-income Cohort  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/19850963?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=5)   Perzanowski MS, Miller RL, Tang D, Ali D, Garfinkel RS, Chew GL, et al.  February 2010

• PBDE Concentrations in Women's Serum and Fecundability. Environ Health Perspect  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20103495)   Harley KG, Marks AR, Chevrier J, Bradman A, Sjödin A, Eskenazi B.  January 2010

• Estrogen Receptor Acting in cis Enhances WT and Mutant p53 Transactivation at Canonical and Noncanonical p53 Target Sequences  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/20080630?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1)   Menendez D, Inga A, Resnick MA.  January 2010

• Acetaminophen Dosing of Humans Results in Blood Transcriptome and Metabolome Changes Consistent with Impaired Oxidative Phosphorylation  [Abstract] (http://www.ncbi.nlm.nih.gov/pubmed/19918972?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=2)   Fannin RD, Russo M, O'Connell TM, Gerrish K, Winnike JH, Macdonald J, et al.  January 2010

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