The Biomedical Translational Research Information System (BTRIS) is a resource available to the NIH intramural community that brings together clinical research data from the Clinical Center and other NIH Institutes and Centers.  BTRIS provides clinical investigators with access to identifiable data for the subjects on their own active protocols, while providing all NIH investigators with access to de-identified data across all protocols.  BTRIS provides users with advanced search, filtering, and aggregation methods to create data sets to support ongoing studies and stimulate ideas for new research.  BTRIS contains subject data from CRIS/MIS (the Clinical Center Medical Information Systems) and research data from NIAID (Crimson), NIAAA, and NCI.  Data are available from 1976 to the present.

BTRIS comprises two distinct but interrelated Web-based applications, BTRIS Data Access and BTRIS Preferences. (Refer to the graphic below)

BTRIS Data Access is the data repository where principal investigators or their designees create reports on their active protocols with identified subject data.  Multiple reports are available in BTRIS and can easily be run by researchers through a series of prompts.  Reports include the IRB Inclusion Enrollment Report, demographics, patient lists, laboratory and microbiology results, vital signs, medication orders and administration, diagnoses, and radiology reports (with links to images in the CC PACS system).

BTRIS Preferences allows principal investigators or their designees to verify subject enrollment in their protocol(s).  This ensures that reports created in BTRIS Data Access include all subjects.  It also allows the principal investigator to designate associate investigators, and other members of the research team, to manage subject enrollment and create reports in BTRIS Data Access.

For questions or comment about BTRIS contact Dr. Jim Cimino, Chief, Laboratory for Informatics Development, NIH Clinical Center, National Institutes of Health, Bethesda, MD
   

This graphic shows the two applications within BTRIS; BTRIS Data Access and BTRIS Preferences. BTRIS Data Access allows researchers to access identified data on active protocols, or de-identified data with approval from the Office of Human Subjects Research. BTRIS Preferences allows researchers to attribute subjects to their protocols, designate alternate users, and set thresholds for e-mail notifications.

NOTE: PDF documents require the free Adobe Reader
Video requires RealPlayer software and high-speed internet connection.