Data Manual for Breast Tissue Microarrays

Progression TMAs

Data variable	Description:	Coding:
Case Type	Identifies type of tissue	Text (Invasive, DCIS, normal breast, normal non-breast, cell line)
Race	ace of patient	Text or blank (White, Black, American Indian, Asian, Unknown)
Age	Age at initial diagnosis	Integer or blank
T Stage	AJCC (version 5) T stage	TIS = Carcinoma In-situ T1 = Tumor < 20 mm T1 = Tumor < 20 mm T1a = Tumor < 5 mm T1b = Tumor > 5 mm and <10 mm T1c = Tumor > 10 mm and < 20 mm T2 = Tumor > 20 mm and < 50 mm T3 = Tumor > 50 mm T4 = Tumor any size + extension T4a = Extension to chest wall T4b = Edema or ulceration or satellite skin nodules T4c = Both T4a and T4b T4d = Inflammatory carcinoma Blank
N Stage	AJCC (version 5) N stage	NX = Minimum req. not met (unknown) N0 = No evidence of regional LN involvement N1 = Mets to movable, ipsilateral node N1a = Only micromets (< 2 mm) N1b = Any nodal mets > 2 mm N1b1 = Mets to 1-3 nodes, any > 2 mm and all <20 mm N1b2 = Mets to 4 or more nodes, any > 2 mm and all < 20 mm N1b3 = Extension of tumor beyond node capsule and < 20 mm N1b4 = Mets to nodes > 20 mm N2 = Mets to ipsilateral nodes that are fixed to one another or to other structures N3 = Mets to ipsilateral internal mammary lymph node Blank
M Stage	AJCC (version 5) M stage	MX = Distant mets not assessed M0 = No known distant mets M1 = Distant mets present Blank
Number of Nodes Positive	Number of nodes positive at initial diagnosis	Integer or blank
Size of Invasive Cancer in cm	Measurement (in cm) of the longest diameter of the tumor	Integer or blank
Total Score	Histologic grade of case	1 = Grade I 2 = Grade II 3 = Grade III Blank
ER	Estrogen receptor status	0 = Negative 1 = Positive Blank
PR	Progesterone receptor status	0 = Negative 1 = Positive Blank
Invasive Link	Coordinates if specimen is matched to an invasive specimen that appears elsewhere on the array	Alphanumeric text or blank