Sandra A. Mitchell
Dr. Sandra A. Mitchell is a Research Scientist and Program Director in the Outcomes Research Branch of the Applied Research Program. Her primary research interests include symptoms and functional status (self-report and performance-based measures) as primary and secondary endpoints in cancer treatment trials, latent variable mixture modeling to characterize heterogeneity in patterns of change over time, and analysis and interpretation issues of patient-reported outcomes, including health-related quality of life. A board certified Acute Care Nurse Practitioner, Dr. Mitchell maintains a clinical practice as an Oncology Nurse Practitioner with the Experimental Transplantation and Immunology Branch, NCI Intramural Program, focusing on long-term survivors of allogeneic hematopoietic stem cell transplantation with Chronic Graft-Versus-Host Disease.
Dr. Mitchell’s work in the Outcomes Research Branch is focused on the development and testing of PRO-CTCAE as a tool to evaluate the symptom experience in patients participating in cancer clinical trials. PRO-CTCAE integrates the patient perspective into the process of adverse event reporting, and may ultimately prove useful as an outcome measure in comparative effectiveness research and to characterize the severity and impact of symptom burden in patients with cancer.
Dr. Mitchell received her undergraduate and master’s degrees from the University of Toronto and the University of Rochester, and received a PhD from the University of Utah with a focus in quantitative methods. The author of numerous peer-reviewed publications in the areas of symptom management, functional status, cancer survivorship, and the application of quality-of-life outcomes in evaluating therapeutic response to treatment, Dr. Mitchell’s work has been recognized with numerous awards, including two NIH Clinical Center Director’s Awards and the Oncology Nursing Society’s Award for Excellence in Nursing-Sensitive Patient Outcomes.
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