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How to Apply

Several online resources are available across the National Institutes of Health to assist small businesses in preparing their grant applications and contract proposals. First-time applicants to the SBIR & STTR Programs are encouraged to review these resources before submitting an application.

Examples of SBIR Grant Applications

The following Phase I and Phase II SBIR examples are provided by NCI's Division of Cancer Control and Population Sciences. Both of these examples are revised applications and include an introductory page with information about changes made to the original application.

Note: The following applications are presented using the PHS398 form pages (with the former page limits), which are no longer current. The National Institutes of Health has transitioned from paper submission of the SBIR and STTR grant applications to electronic submission via the web portal of Grants.gov. Please reference the links shown below under "Electronic Grant Submission" for the most current information on how to submit an electronic SBIR or STTR grant application.

NCI SBIR Phase I Grant Application
NCI SBIR Phase II Grant Application

Electronic Grant Submission

Electronic Submission Process and Resources

Note: Contract proposals are received via paper submission only.

Tips for Applying

Nature Biotechnology Publishes Article on the SBIR & STTR Programs

In an article published in Nature Biotechnology, SBIR & STTR Development Center staff discuss the application process and provide tips for applying for funding through the SBIR & STTR Programs. The article highlights the important steps to consider in the process of writing a competitive application that will best showcase your products and technologies for the cancer community. Please click here to read the article and learn about how the SBIR & STTR Programs not only provide funding, but also help small businesses find ways to connect and collaborate with potential investors.

Please click here to download presentations from the NCI SBIR & STTR Programs that will help small businesses prepare and submit successful applications for funding.