Friday, November 21, 2003, 20:10 EST (08:10 PM EST)
CDCHAN-00165-03-11-21-UPD-N
Preliminary Report of Avian Influenza A (H9N2) Virus Infection in a Child in Hong Kong
Current surveillance data indicate that the United States is experiencing an early influenza season that could be more severe than in the past 3 years. The situation underscores the need for timely immunization of those people most at risk from serious complications of influenza and the people taking care of them, especially health-care workers.
The United States and some European countries are experiencing influenza morbidity earlier than usual. So far, the majority of the influenza viruses identified in the United States this winter have been type A (H3N2) viruses, which historically have been associated with relatively severe influenza epidemics. Of the influenza A(H3N2) viruses from the United States that have been analyzed at CDC, 78% are similar to the A/Fujian/411/2002 strain, which evolved or "drifted from the A/Panama/2007/99 strain present in the current vaccine, and the remaining 22% are similar to the vaccine strain. The A/Fujian/411/2002 drift variant was the predominant influenza strain circulating in Australia and New Zealand during their most recent influenza season, which was characterized as "moderately severe." These factors could portend higher morbidity and mortality in the United States during the 2003-04 influenza season.
The influenza vaccine is safe and is the most effective way to prevent the disease and its complications. Although this year's vaccine contains the Panama strain of influenza A (H3N2), it is expected to provide some cross-protection against the Fujian-like viruses that are currently circulating. The other two virus strains (influenza A[H1N1] and influenza B) in the vaccine closely match their circulating counterparts.
CDC recommends the following individuals get vaccinated against influenza:
· persons 50 years and older;
· residents of nursing homes and other long-term care facilities that house persons of any age who have long-term illnesses;
· adults and children 6 months of age and older who have chronic heart or lung conditions, including asthma;
· adults and children 6 months of age and older who need regular medical care or had to be in a hospital because of metabolic diseases (like diabetes), chronic kidney disease, or weakened immune system (including immune system problems caused by medicine or by infection with HIV);
· children and teenagers (6 months to 18 years of age) who are on long-term aspirin therapy and therefore could develop Reye syndrome after influenza;
· women who will be more than 3 months pregnant during the influenza season.
In addition, CDC recommends vaccination of the following groups of people to reduce the risk of spreading influenza to persons at high risk for complications:
· doctors, nurses, and other employees in hospitals and doctors' offices, including emergency response workers;
· employees of nursing homes and long-term care facilities who have contact with patients or residents;
· employees of assisted living and other residences for people in high-risk groups;
· people who provide home care to those in high-risk groups;
· household members (including children) of people in high-risk groups.
CDC also encourages, when feasible, vaccination of children aged 6-23 months and their caregivers.
The primary contraindication to influenza vaccination is allergy to eggs. For more information about influenza, visit CDC's Web site at www.cdc.gov.
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