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Smallpox Vaccine

Information for the General Public

Information for health professionals can be found on the Smallpox Vaccination page.

What You Need to Know About the Smallpox Vaccine

  • Smallpox Vaccine Overview
    The smallpox vaccine helps the body develop immunity to smallpox. Currently, the U.S. has a big enough stockpile to vaccinate everyone who might need it in the event of an emergency…
  • The Live Virus Smallpox Vaccine
    The vaccinia virus is the "live virus" used in the vaccine. It is a "pox"-type virus related to smallpox. When given to humans as a vaccine, it helps the body to develop immunity to smallpox…
  • Frequently Asked Questions About Smallpox Vaccine
    How long does a smallpox vaccination last? Is it possible for people to get smallpox from the vaccination? CDC answers common questions such as these…

What Happens After Vaccination?

  • Side Effects of Vaccination
    For most people, the smallpox vaccine is safe & effective. Most people experience normal, typically mild reactions to the vaccine, which indicate that it is beginning to work. Some people may experience reactions that may require medical attention…
  • Someone You Are Close to May Get the Smallpox Vaccine: What You Should Know and Do
    If someone you have close, physical contact with (your spouse, partner or other member of your household) is considering getting the smallpox vaccine, there are some things you should know…

What to Know If You're Considering Vaccination

Frequently Asked Questions

Related Resources

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