Biologic Specimen and Data Repository Information Coordinating Center
Home > Studies > NGHS

Resources Available

Specimens and Study Datasets

Materials Available

SERUM 14,857

Study Documents

PDF Data Dictionary (PDF - 923.7 KB)
Forms (HTML )
PDF Protocol (PDF - 3.1 MB)
PDF Summary of Collected Data (PDF - 4.2 MB)

Persons using assistive technology may not be able to fully access information in the study documents. For assistance, Contact BioLINCC and include the web address and/or publication title in your message.

If you need help accessing information in different file formats such as PDF, XLS, DOC, see Instructions for Downloading Viewers and Players.

NHLBI Growth and Health Study (NGHS)

Clinical Trials URL: http://www.clinicaltrials.gov/ct2/s...
Study Type: Epidemiology Study
Prepared on October 13, 2008
Last Updated on January 27, 2006
Study Dates: 1985-2000
Consent: Unrestricted Consent
Commercial Use Restrictions: No
NHLBI Division: DCVS
Collection Type: Open BioLINCC Study - See bottom of this webpage for request information

Objectives

To investigate racial differences in dietary, physical activity, family, and psychosocial factors associated with the development of obesity from pre-adolescence through maturation between African-American and white girls. Secondarily, the NGHS sought to examine the effects of obesity on cardiovascular disease risk factors.

Background

Obesity is a major contributing factor to several predictors of coronary heart disease such as hypertension, a poor lipid profile and diabetes. Both genetic and environmental factors play a significant role in the development of obesity, and there is evidence to suggest that obesity in childhood will likely carry over into adulthood. Prevention of obesity in early childhood could provide significant long term health benefits. A greater understanding of the factors contributing to childhood obesity is required for the establishment of effective weight reduction intervention programs. To this end, the National Growth and Health Study was initiated in 1985 as a multicenter study of the development of obesity among black and white pre-adolescent girls.

Subjects

The NHLBI National Growth and Health Study recruited girls 9 and 10 years of age in two communities (Richmond, California and Cincinnati, Ohio) and also from families enrolled in a health maintenance organization in the Washington, D.C. area. A total of 2,379 girls were enrolled in the study between 1987-88 and were followed for 9 years. Slightly more than half of the cohort was African-American.

Design

Subjects had annual examinations, and data collected included: physical examination, anthropometric measurements, dietary information including food pattern and nutrient intake, physical activity, lipid, lipoprotein, and apolipoprotein profiles, family socioeconomic status, and psychosocial information.


Requests for Open BioLINCC Studies are submitted through this website. Click the Request button to begin.