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2002 Publications

  1. Abernethy DR, Pezzullo J, Mascelli MA, Frederick B, Kleiman NS, Freedman J. Pharmacodynamicis of abciximab during angioplasty: Comparison of healthy subjects. Clin Pharmacol Ther 2002;71(3):186-195.

  2. Abernethy DR, Ruffolo RR. International union of pharmacology nomenclature and pharmacological reviews. Pharmacol Rev 2002;54(2):159.

  3. Abernethy DR, Soldatov NM. Structure-functional diversity of human L-type Ca(2+) channel: perspectives for new pharmacological targets. J Pharmacol Exp Ther 2002;300:724-728.

  4. Alexander GE, Chen K, Pietrini P, Rapoport SI, Reiman EM. Longitudinal PET evaluation of cerebral metabolic decline in dementia: a potential outcome measure in Alzheimer's disease treatment studies. Am J Psychiatry 2002;159(5):738-745.

  5. Allen DD, Cardenas AM, Arriagada C, Bennett LB, Garcia CJ, Caviedes R, Rapoport SI, Caviedes P. A dorsal root ganglia cell line derived from trisomy 16 fetal mice, a model for Down syndrome. Neuroreport 2002;13(4):491-496.

  6. Alves Da Costa C, Paitel E, Mattson MP, Amson R, Telerman A, Ancolio K, Checler F. Wild-type and mutated presenilins 2 trigger p53-dependent apoptosis and down-regulate presenilin 1 expression in HEK293 human cells and in murine neurons. Proc Natl Acad Sci USA 2002;99(6):4043-4048.

  7. Anderson DE, Chesney MA. Gender-specific association of perceived stress and inhibited breathing pattern. Int J Behav Med. 2002;9(3):216-227.

  8. Anisimov SV, Tarasov KV, Riordon D, Wobus AM, Boheler KR. SAGE identification of differentiation responsive genes in P19 embryonic cells induced to form cardiomyocytes in vitro. Mech Dev. 2002;117(1-2):25-74.

  9. Anisimov SV, Tarasov KV, Stern MD, Lakatta, EG, Boheler KR. A quantitative and validated SAGE transcriptome reference for adult mouse heart. Genomics 2002;80:213-222.

  10. Anisimov SV, Tarasov KV, Tweedie D, Stern MD, Wobus AM, Boheler KR. SAGE identificaiton of gene transcripts with profiles unique to pluripotent mouse R1 embryonic stem cells. Genomics 2002;79:169-176.

  11. Arikawa-Hirasawa E, Le AH, Nishino I, Nonaka I, Ho NC, Francomano CA, Govindraj P, Hassell JR, Devaney JM, Spranger J, Stevenson RE, Iannaccone S, Dalakas MC, Yamada Y. Structural and functional mutations of the perlecan gene cause Schwartz-Jampel syndrome, with myotonic myopathy and chondrodysplasia. Am J Hum Genet 2002;70(5):1368-1375.

  12. Bagrov AY, Bagrov YY, Fedorova OV, Kashkin VA, Patkina NA, Zvartau EE. Endogenous digitalis-like ligands of the sodium pump: possible involvement in mood control and ethanol addiction. Eur Neuropsychopharmacol 2002;12:1-12.

  13. Bandinelli S, Lauretani F, Benvenuti E, Corsi A, De Marco MF, Bartali B, Ruotolo G, Miniati B, Macchi C, Russo CR, Guralnik JM, Ferrucci L. Understanding the physiological and functional consequences of menopause: the PROSALMEN study. PROgetto SALute MENopausa. Aging Clin Exp Res. 2002;14(3):170-177.

  14. Baynham MT, Patel S, Moaddel R, Wainer IW. Multidimensional on-line screening for ligands to the alpha3beta4 neuronal nicotinic acetylcholine receptor using an immobilized nicotinic receptor liquid chromatographic stationary phase. J Chromatogr B Analyt Technol Biomed Life Sci. 2002;772(1):155-161.

  15. Berndt SI, Carter HB, Landis PK, Tucker KL, Hsieh LJ, Metter EJ, Platz EA. Calcium intake and prostate cancer risk in a long-term aging study: the Baltimore Longitudinal Study of Aging. Urology. 2002;60(6):1118-1123.

  16. Birukov KG, Birukova AA, Dudek SM, Verin AD, Crow MT, Zhan X, DePaola N, Garcia JG. Shear stress-mediated cytoskeletal remodeling and cortactin translocation in pulmonary endothelial cells. Am J Respir Cell Mol Biol 2002;26(4):453-464.

  17. Black A, Lane MA. Nonhuman primate models of skeletal and reproductive aging. Gerontology 2002;48:72-80.

  18. Blanc S, Colligan AS, Trabulsi J, Harris T, Everhart JE, Bauer D, Schoeller DA. Influence of delayed isotopic equiliberation in urine on the accuracy of the (2)H(2)(18)O method in the elderly. J Appl Physiol 2002;92(3):1036-1044.

  19. Boheler KR, Czyz J, Tweedie D, Yang HT, Anisimov SV, Wobus AM. Differentiation of pluripotent embryonic stem cells into cardiomyocytes. Circ Res. 2002;91(3):189-201.

  20. Bohr VA. DNA damage and its processing. Relation to human disease. J Inherit Metab Dis 2002;25:215-222.

  21. Bohr VA. DNA damage. In: Wiley Encyclopedia of Molecular Medicine, John Wiley and Sons, Inc., 2002, pp.1067-1070.

  22. Bohr VA. Human premature aging syndromes and genomic instability. Mech Ageing Dev. 2002;123(8):987-993.

  23. Bohr VA. Repair of oxidative DNA damage in nuclear and mitochondrial DNA, and some changes with aging in mammalian cells(1,2). Free Radic Biol Med 2002;32(9):804-812.

  24. Bohr VA, Brosh RM Jr, von Kobbe C, Opresko P, Karmakar P. Pathways defective in the human premature aging disease Werner syndrome. Biogerontology 2002;3(1-2):89-94.

  25. Bohr VA, Stevnsner T, de Souza-Pinto NC. Mitochondrial DNA repair of oxidative damage in mammalian cells. Gene 2002;286(1):127-134.

  26. Boon K, Osorio EC, Greenhut SF, Schaefer CF, Shoemaker J, Polyak K, Morin PJ, Buetow KH, Strausberg RL, De Souza SJ, Riggins GJ. An anatomy of normal and malignant gene expression. Proc Natl Acad Sci USA. 2002;99(17):11287-11292.

  27. Bosetti F, Brizzi F, Barogi S, Mancuso M, Siciliano G, Tendi EA, Murri L, Rapoport SI, Solaini G. Cytochrome c oxidase and mitochondrial F(1)F(0)-ATPase (ATP synthase) activities in platelets and brain from patients with Alzheimer's disease. Neurobiol Aging 2002;23(3):371-376.

  28. Bosetti F, Rintala J, Seemann R, Rosenberger TA, Contreras MA, Rapoport SI, Chang MC. Chronic lithium downregulates cyclooxygenase-2 activity and prostaglandin E(2) concentration in rat brain. Mol Psychiatry. 2002;7(8):845-850.

  29. Bosetti F, Seemann R, Bell JM, Zahorchak R, Friedman E, Rapoport SI, Manickam P. Analysis of gene expression with cDNA microarrays in rat brain after 7 and 42 days of oral lithium administration. Brain Res Bull 2002;57(2):205-209.

  30. Bosetti F, Seemann R, Rapoport SI. Chronic lithium chloride administration to rats decreases brain protein level of epsilon (epsilon) subunit of eukaryotic initiation factor-2B. Neurosci Lett. 2002;327(1):71-73.

  31. Brosh RM Jr. Functions of the Werner syndrome protein as caretaker of the human genome. Recent Res Devel Biol Chem. 2002;1:183-207.

  32. Brosh RM, Bohr VA. Roles of the Werner syndrome protein in pathways required for maintenance of genome stability. Exp Gerontol 2002;37:491-506.

  33. Brosh RM Jr, Driscoll HC, Dianov GL, Sommers JA. Biochemical characterization of the WRN-FEN-1 functional interaction. Biochemistry. 2002;41(40):12204-12216.

  34. Brosh RM Jr, Waheed J, Sommers JA. Biochemical characterization of the DNA substrate specificity of Werner syndrome helicase. J Biol Chem 2002;277(26):23236-23245.

  35. Buerger K, Zinkowski R, Teipel SJ, Tapiola T, Arai H, Blennow K, Andreasen N, Hofmann-Kiefer K, DeBernardis J, Kerkman D, McCulloch C, Kohnken R, Padberg F, Pirttila T, Schapiro MB, Rapoport SI, Moller HJ, Davies P, Hampel H. Differential diagnosis of Alzheimer disease with cerebrospinal fluid levels of tau protein phosphorylated at threonine 231. Arch Neurol. 2002;59(8):1267-1272.

  36. Cai J, Rao MS. Stem cell and precursor cell therapy. Neuromolecular Med. 2002;2(3):233-249.

  37. Caldwell MC, Hough C, Furer S, Linehan WM, Morin PJ, Gorospe M. Serial analysis of gene expression in renal carcinoma cells reveals VHL-dependent sensitivity to TNF alpha cytotoxicity. Oncogene 2002;21:929-936.

  38. Cardenas AM, Allen DD, Arriagada C, Olivares A, Bennett LB, Caviedes R, Dagnino-Subiabre A, Mendoza IE, Segura-Aguilar J, Rapoport SI, Caviedes P. Establishment and characterization of immortalized neuronal cell lines derived from the spinal cord of normal and trisomy 16 fetal mice, an animal model of Down syndrome. J Neurosci Res 2002;68(1):46-58.

  39. Chan SL, Culmsee C, Haughey N, Klapper W, Mattson MP. Presenilin-1 mutations sensitize neurons to DNA damage-induced death by a mechanism involving perturbed calcium homeostasis and activation of calpains and caspase-12. Neurobiol Dis. 2002;11(1):2-19.

  40. Chan SL, Furukawa K, Mattson MP. Presenilins and APP in neuritic and synaptic plasticity: implications for the pathogenesis of Alzheimer's disease. Neuromolecular Med. 2002;2(2):167-196.

  41. Chan SL, Pedersen WA, Zhu H, Mattson MP. Numb modifies neuronal vulnerability to amyloid beta-peptide in an isoform-specific manner by a mechanism involving altered calcium homeostasis: implications for neuronal death in Alzheimer's disease. Neuromolecular Med 2002;1(1):55-67.

  42. Chaves PH, Ashar B, Guralnik JM, Fried LP. Looking at the relationship between hemoglobin concentration and prevalent mobility difficulty in older women. Should the criteria currently used to define anemia in older people be reevaluated? J Am Geriatr Soc. 2002;50(7):1257-1264.

  43. Chen GS, Jaradat SA, Banerjee N, Tanaka TS, Ko MSH, Zhang MQ. Evaluation and comparison of clustering algorithms in analyzing es cell gene expression data. Statistica Sinica 2002;12:241-262.

  44. Chen P, Li J, Barnes J, Kokkonen GC, Lee JC, Liu Y. Restraint of proinflammatory cytokine biosynthesis by mitogen-activated protein kinase phosphatase-1 in lipopolysaccharide-stimulated macrophages. J Immunol. 2002;169(11):6408-6416.

  45. Chen P, Hutter D, Liu P, Liu Y. A mammalian expression system for rapid production and purificaton of active MAP kinase phosphatases. Protein Expr Purif 2002;24(3):481-488.

  46. Cheng G, Yu Z, Zhou D, Mattson MP. Phosphatidylinositol-3-kinase-Akt kinase and p42/p44 mitogen-activated protein kinases mediate neurotrophic and excitoprotective actions of a secreted form of amyloid precursor protein. Exp Neurol. 2002;175(2):407-414.

  47. Cheng H, Wang SQ. Calcium signaling between sarcolemmal calcium channels and ryanodine receptors in heart cells. Front Biosci. 2002;7:D1867-D1878.

  48. Chiao E, Fisher P, Crisponi L, Deiana M, Dragatsis I, Schlessinger D, Pilia G, Efstratiadis A. Overgrowth of a mouse model of the Simpson-Golabi-Behmel syndrome is independent of IGF signaling. Dev Biol 2002;243:185-206.

  49. Cho YS, Kim MK, Cheadle C, Neary C, Park YG, Becker KG, Cho-Chung YS. A genomic-scale view of the cAMP response element-enhancer decoy: a tumor target-based genetic tool. Proc Natl Acad Sci USA. 2002;99(24):15626-15631.

  50. Cho-Chung YS, Nesterova M, Becker KG, Srivastava R, Park YG, Lee YN, Cho YS, Kim MK, Neary C, Cheadle C. Dissecting the circuitry of protein kinase A and cAMP signaling in cancer genesis: antisense, microarray, gene overexpression, and transcription factor decoy. Ann NY Acad Sci. 2002;968:22-36.

  51. Christmas C, O'Connor KG, Harman SM, Tobin JD, Munzer R, Bellantoni MF, St. Clair C, Pabst KM, Sorkin JD, Blackman MR. Growth hormone and sex steroid effects on bone metabolism and bone mineral density in healthy aged women and men. J Gerontol 2002;57A:M12-M18.

  52. Compton D, Wavrant DeVrieze F, Petersen R, Tangalos E, Li L, Hardy J. Possible association between genetic variability at the apolipoprotein(a) locus and Alzheimer's disease in apolipoprotein E2 carriers. Neurosci Lett. 2002;331(1):60.

  53. Conant K, Haughey N, Nath A, St Hillaire C, Gary DS, Pardo CA, Wahl LM, Bilak M, Milward E, Mattson MP. Matrix metalloproteinase-1 activates a pertussis toxin-sensitive signaling pathway that stimulates the release of matrix metalloproteinase-9. J Neurochem. 2002;82(4):885-893.

  54. Contreras MA, Rapoport SI. Recent studies on interactions between n-3 and n-6 polyunsaturated fatty acids in brain and other tissues. Curr Opin Lipidol. 2002;13(3):267-272.

  55. Correia LC, Lakatta EG, O'Connor FC, Becker LC, Clulow J, Townsend S, Gerstenblith G, Fleg JL. Attenuated cardiovascular reserve during prolonged submaximal cycle exercise in healthy older subjects. J Am Coll Cardiol. 2002;40(7):1290-1297.

  56. Corti MC, Guralnik JM, Sartori L, Baggio G, Manzato E, Pezzotti P, Barbato G, Zambon S, Ferrucci L, Minervini S, Musacchio E, Crepaldi G. The effect of cardiovascular and osteoarticular diseases on disability in older Italian men and women: rationale, design, and sample characteristics of the Progetto Veneto Anziani (PRO.V.A.) study. J Am Geriatr Soc. 2002;50(9):1535-1540.

  57. Costa PT Jr, Herbst JH, McCrae RR, Samuels J, Ozer DJ. The replicability and utility of three personality types. Eur J Pers 2002;16:S73-S87.

  58. Costa PT Jr, Widiger TA (eds.) Personality disorders and the five-factor model of personality, 2nd Edition. Washington, DC: American Psychological Association, 2002.

  59. Crow MT. Beta-adrenergic receptor signaling pathways mediating cell survival in cardiomyocytes: a role for PKC epsilon inhibition? J Mol Cell Cardiol. 2002;34(9):1121-1125.

  60. Crow MT. Hypoxia, BNip3 proteins, and the mitochondrial death pathway in cardiomyocytes. Circ Res. 2002;91(3):183-185.

  61. Cui CY, Durmowicz M, Tanaka TS, Hartung AJ, Tezuka T, Hashimoto K, Ko MS, Srivastava AK, Schlessinger D. EDA targets revealed by skin gene expression profiles of wild-type, Tabby and Tabby EDA-A1 transgenic mice. Hum Mol Genet. 2002;11(15):1763-1773.

  62. Cutler RG, Pedersen WA, Camandola S, Rothstein JD, Mattson MP. Evidence that accumulation of ceramides and cholesterol esters mediates oxidative stress-induced death of motor neurons in amyotrophic lateral sclerosis. Ann Neurol. 2002;52(4):448-457.

  63. Davatzikos C, Resnick SM. Degenerative age changes in white matter connectivity visualized in vivo using Magnetic Resonance Imaging. Cereb Cortex. 2002;12(7):767-771.

  64. de Souza-Pinto NC, Bohr VA. The mitochondrial theory of aging: involvement of mitochondrial DNA damage and repair. Int Rev Neurobiol. 2002;53:519-534.

  65. Demehin AA, Abugo OO, Jayakumar R, Lakowicz JR, Rifkind JM. Binding of hemoglobin to red cell membranes with eosin-5-maleimide-labeled band 3: analysis of centrifugation and fluorescence data. Biochemistry. 2002;41(27):8630-8637.

  66. den Heijer T, Oudkerk M, Launer LJ, van Duijn CM, Hofman A, Breteler MM. Hippocampal, amygdalar, and global brain atrophy in different apolipoprotein E genotypes. Neurology. 2002;59(5):746-748.

  67. Dolan NC, Liu K, Criqui MH, Greenland P, Guralnik JM, Chan C, Schneider JR, Mandapat AL, Martin G, McDermott MM. Peripheral artery disease, diabetes, and reduced lower extremity functioning. Diabetes Care 2002;25:113-120.

  68. Duan W, Ladenheim B, Cutler RG, Kruman II, Cadet JL, Mattson MP. Dietary folate deficiency and elevated homocysteine levels endanger dopaminergic neurons in models of Parkinson's disease. J Neurochem 2002;80:101-110.

  69. Duan W, Zhu X, Ladenheim B, Yu QS, Guo Z, Oyler J, Cutler RG, Cadet JL, Greig NH, Mattson MP. p53 inhibitors preserve dopamine neurons and motor function in experimental parkinsonism. Ann Neurol. 2002;52(5):597-606.

  70. Durmowicz MC, Cui CY, Schlessinger D. The EDA gene is a target of, but does not regulate Wnt signaling. Gene. 2002;285(1-2):203-211.

  71. Egan JM, Clocquet AR, Elahi D. The insulinotropic effect of acute exendin-4 administered to humans: comparison of nondiabetic state to type 2 diabetes. J Clin Endocrinol Metab 2002;87:1282-1290.

  72. Egan JM, Meneilly GS, Habener JF, Elahi D. Glucagon-like peptide-1 augments insulin-mediated glucose uptake in the obese state. J Clin Endocrinol Metab. 2002;87(8):3768-3773.

  73. Elahi D, Muller DC, Egan JM, Andres R, Veldhuist J, Meneilly GS. Glucose tolerance, glucose utilization and insulin secretion in ageing. Novartis Found Symp 2002;242: 222-242.

  74. Espinoza-Delgado I. Cancer vaccines. Oncologist. 2002;7 Suppl 2:20-33.

  75. Espinoza-Delgado, E., Longo, D.L.: Non-Hodgkin's lymphoma. In Laughlin, J.J., and Lazarus, H.M. (Eds.): Allogeneic Stem Cell Transplantation: Clinical Research and Practice, Totowa, N.J., Humana Press, 2002, pp. 83-99.

  76. Fan J, Yang X, Wang W, Wood WH 3rd, Becker KG, Gorospe M. Global analysis of stress-regulated mRNA turnover by using cDNA arrays. Proc Natl Acad Sci USA. 2002;99(16):10611-10616.

  77. Fang J, Metter EJ, Landis P, Carter HB. PSA velocity for assessing prostate cancer risk in men with PSA levels between 2.0 and 4.0 ng/ml.Urology 2002;59(6):889-893.

  78. Fant M, Weisoly DL, Cocchia M, Huber R, Khan S, Lunt T, Schlessinger D. PLAC1, a trophoblast-specific gene, is expressed throughout pregnancy in the human placenta and modulated by keratinocyte growth factor. Mol Reprod Dev. 2002;63(4):430-436.

  79. Fedorova OV, Dorofeeva NA, Lopatin DA, Lakatta EG, Bagrov AY. Phorbol diacetate potentiates na(+)-k(+) ATPase inhibition by a putative endogenous ligand, marinobufagenin. Hypertension 2002;39:298-302.

  80. Fedorova OV, Talan MI, Agalakova NI, Lakatta EG, Bagrov AY. Endogenous ligand of alpha(1) sodium pump, marinobufagenin, is a novel mediator of sodium chloride dependent hypertension. Circulation 2002;105:1122-1127.

  81. Feiveson AH, Metter EJ, Paloski WH. A statistical model for interpreting computerized dynamic posturography data. IEEE Trans Biomed Eng. 2002;49(4):300-309.

  82. Ferrucci L, Cavazzini C, Corsi A, Bartali B, Russo CR, Lauretani F, Ferrucci L, Cavazzini C, Corsi AM, Bartali B, Russo CR, Lauretani F, Bandinelli S, Bandinelli S, Guralnik JM. Biomarkers of frailty in older persons. J Endocrinol Invest. 2002;25(10 Suppl):10-15.

  83. Ferrucci L, Penninx BW, Volpato S, Harris TB, Bandeen-Roche K, Balfour J, Leveille SG, Fried LP, Md JM. Change in muscle strength explains accelerated decline of physical function in older women with high interleukin-6 serum levels. J Am Geriatr Soc. 2002;50(12):1947-1954.

  84. Ferrucci L, Russo CR, Lauretani F, Bandinelli S, Guralnik JM. A role for sarcopenia in late-life osteoporosis. Aging (Milano). 2002;14(1):1-4.

  85. Fleg JL. Can exercise conditioning be effective in older heart failure patients? Heart Fail Rev 2002;7:99-103.

  86. Foley DJ, Heimovitz HK, Guralnik JM, Brock DB. Driving life expectancy of persons aged 70 years and older in the United States. Am J Public Health. 2002;92(8):1284-1289.

  87. Foley DJ, White LR. Dietary intake of antioxidants and risk of Alzheimer disease: food for thought. JAMA. 2002;287(24):3261-3263.

  88. Freedman J, Mascelli MA, Pezzullo JC, Barnathan ES, Frederick B, Jordan RE, Abernethy DR. Pharmacodynamic profile of short-term readministration of abciximab in healthy subjects. Am Heart J 2002;143:87-94.

  89. Fridman AI, Matveev SA, Agalakova NI, Fedorova OV, Lakatta EG, Bagrov AY. Marinobufagenin, an endogenous ligand of alpha-1 sodium pump, is a marker of congestive heart failure severity. J Hypertens 2002;20(6):1189-1194.

  90. Fu W, Lee J, Guo Z, Mattson MP. Seizures and tissue injury induce telomerase in hippocampal microglial cells. Exp Neurol. 2002;178(2):294-300.

  91. Fu W, Lu C, Mattson MP. Telomerase mediates the cell survival-promoting actions of brain-derived neurotrophic factor and secreted amyloid precursor protein in developing hippocampal neurons. J Neurosci. 2002;22(24):10710-10719.

  92. Gaines JM, Talbot LA, Metter EJ. The relationship of arthritis self-efficacy to functional performance in older men and women with osteoarthritis of the knee. Geriatr Nurs. 2002;23(3):167-170.

  93. Gary DS, Getchell TV, Getchell ML, Mattson MP. Olfactory bulbectomy protects hippocampal pyramidal neurons against excitotoxic death. Exp Neurol. 2002;176(1):266-268.

  94. Gearhart PJ. Immunology: the roots of antibody diversity. Nature. 2002;419(6902):29-31.

  95. Geleijnse JM, Launer LJ, Van der Kuip DA, Hofman A, Witteman JC. Inverse association of tea and flavonoid intakes with incident myocardial infarction: the Rotterdam Study. Am J Clin Nutr 2002;75(5):880-886.

  96. Ghosh P, Buchholz MA, Yano S, Taub D, Longo DL. Effect of rapamycin on the cyclosporin A-resistant CD28-mediated costimulatory pathway. Blood 2002;99(12):4517-4524.

  97. Gilman CP, Mattson MP. Do apoptotic mechanisms regulate synaptic plasticity and growth-cone motility? Neuromolecular Med. 2002;2(2):197-214.

  98. Giovacchini G, Chang MC, Channing MA, Toczek M, Mason A, Bokde AL, Connolly C, Vuong BK, Ma Y, Der MG, Doudet DJ, Herscovitch P, Eckelman WC, Rapoport SI, Carson RE. Brain incorporation of [11C]arachidonic acid in young healthy humans measured with positron emission tomography. J Cereb Blood Flow Metab. 2002;22(12):1453-1462.

  99. Gorospe M. Regulation of mRNA turnover by cellular stress. In: Handbook of Cellular Signaling. Bradshaw RA, E Dennis (Eds.): Academic Press, 2002.

  100. Greig NH, Lahiri DK, Sambamurti K. Butyrylcholinesterase: an important new target in Alzheimer's disease therapy. Int Psychogeriatr. 2002;14 Suppl 1:77-91.

  101. Guralnik JM, Alecxih L, Branch LG, Wiener JM. Medical and long-term care costs when older persons become more dependent. Am J Public Health. 2002;92(8):1244-1245.

  102. Guralnik JM, Ferrucci L. Underestimation of disability occurrence in epidemiological studies of older people: is research on disability still alive? J Am Geriatr Soc. 2002;50(9):1599-1601.

  103. Guralnik JM, Melzer D. Chronological and functional ageing. In: Copeland JRM, Abou-Saleh MT, Blazer DG, eds. Principles and practice of geriatric psychiatry, 2nd edition. Chichester, UK: John Wiley and Sons. 2002:71-74.

  104. Gustafsson AB, Sayen MR, Williams SD, Crow MT, Gottlieb RA. TAT protein transduction into isolated perfused hearts: TAT-apoptosis repressor with caspase recruitment domain is cardioprotective. Circulation. 2002;106(6):735-739.

  105. Hagemann D, Naumann E, Thayer JF, Bartussek D. Does resting electroencephalograph asymmetry reflect a trait? an application of latent state-trait theory. J Pers Soc Psychol 2002;82(4):619-641.

  106. Hagemann D, Xiao RP. Dual site phospholamban phosphorylation and its physiological relevance in the heart. Trends Cardiovasc Med 2002;12:51-56.

  107. Hampel H, Teipel SJ, Alexander GE, Pogarell O, Rapoport SI, Moller HJ. in vivo imaging of region and cell type specific neocortical neurodegeneration in Alzheimer's disease. Perspectives of MRI derived corpus callosum measurement for mapping disease progression and effects of therapy. Evidence from studies with MRI, EEG and PET. J Neural Transm. 2002;109(5-6):837-855.

  108. Hampel H, Teipel SJ, Bayer W, Alexander GE, Schwarz R. Schapiro MB, Rapoport SI, Moller HJ. Age transformation of combined hippocampus and amygdala volume improves diagnostic accuracy in Alzheimer's disease. J Neurol Sci 2002;194:15-19.

  109. Hardy J. Pathways to primary neurodegenerative disease. Neurologia. 2002;17(8):399-401.

  110. Hardy J. Testing times for the "amyloid cascade hypothesis". Neurobiol Aging. 2002;23(6):1073-1074.

  111. Hardy J, Gwinn-Hardy K, McGeer P, Morris H, Perez-Tur J, Steele J. Clinical features and changing patterns of neurodegenerative disorders on Guam, 1997-2000. Neurology. 2002;59(7):1121.

  112. Hardy J, Selkoe DJ. The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics. Science. 2002;297(5580):353-356.

  113. Harik-Khan RI, Fleg JL, Wise RA. Body mass index and the risk of COPD. Chest 2002;121:370-376.

  114. Harris TB. Invited commentary: Body composition in studies of aging: new opportunities to better understand health risks associated with weight. Am J Epidemiol. 2002;156(2):122-124.

  115. Haughey NJ, Liu D, Nath A, Borchard AC, Mattson MP. Disruption of neurogenesis in the subventricular zone of adult mice, and in human cortical neuronal precursor cells in culture, by amyloid beta-peptide: implications for the pathogenesis of Alzheimer's disease. Neuromolecular Med. 2002;1(2):125-135.

  116. Haughey NJ, Mattson MP. Calcium dysregulation and neuronal apoptosis by the HIV-1 proteins tat and gp120. J Acquir Immune Defic Syndr. 2002;31 Suppl 2:S55-61.

  117. Haughey NJ, Nath A, Chan SL, Borchard AC, Rao MS, Mattson MP. Disruption of neurogenesis by amyloid beta-peptide, and perturbed neural progenitor cell homeostasis, in models of Alzheimer's disease. J Neurochem. 2002;83(6):1509-1524.

  118. Havlik RJ, Foley DJ, Sayer B, Masaki K, White L, Launer LJ. Variability in midlife systolic blood pressure is related to late-life brain white matter lesions: The Honolulu-Asia Aging Study. Stroke 2002;33:26-30.

  119. Henry CJK, Ritz P, Roth GS, Lane MA, Solomons NW. Report on the IDECG Working Group on the Biology of Aging. Euro J Clin Nutr 2002;Vol 54, Supplement 3, S157-S159.

  120. Hees PS, Fleg JL, Lakatta EG, Shapiro EP. Left ventricular remodeling with age in normal men versus women: novel insights using three-dimensional magnetic resonance imaging. Am J Cardiol. 2002;90(11):1231-1236.

  121. Hillis AE, Wityk RJ, Barker PB, Beauchamp NJ, Gailloud P, Murphy K, Cooper O, Metter EJ. Subcortical aphasia and neglect in acute stroke: the role of cortical hypoperfusion. Brain 2002;125(Pt 5):1094-1104.

  122. Ho NC, Hadley DW, Jain PK, Francomano CA. Case 47: dural ectasia associated with Marfan syndrome. Radiology. 2002;223(3):767-771.

  123. Hodes RJ, Hathcock KS, Weng NP. Telomeres in T and B cells. Nat Rev Immunol. 2002;2(9):699-706.

  124. Holsinger T, Steffens DC, Phillips C, Helms MJ, Havlik RJ, Breitner JC, Guralnik JM, Plassman BL. Head injury in early adulthood and the lifetime risk of depression. Arch Gen Psychiatry 2002;59:17-22.

  125. Horska A, Kaufmann WE, Brant LJ, Naidu S, Harris JC, Barker PB. In vivo quantitative proton MRSI study of brain development from childhood to adolescence. J Magn Reson Imaging 2002;15:137-143.

  126. Hu L, Rezanka LJ, Mi QS, Lustig A, Taub DD, Longo DL, Kenny JJ. T15-idiotype negative B cells dominate the phosphocholine binding cells in the preimmune repertoire of T15i knockin mice. J Immunol 2002;168(3):1273-1280.

  127. Hurlbut DE, Lott ME, Ryan AS, Ferrell RE, Roth SM, Ivey FM, Martel GF, Lemmer JT, Fleg JL, Hurley BF. Does age, sex, or ACE genotype affect glucose and insulin responses to strength training? J Appl Physiol 2002;92:643-650.

  128. Hutter D, Chen P, Li J, Barnes J, Liu Y. The carboxyl-terminal domains of MKP-1 and MKP-2 have inhibitory effects on their phosphatase activity. Mol Cell Biochem. 2002;233(1-2):107-117.

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