NIH Blueprint for Neuroscience Research

• NIH Toolbox for Assessment of Neurological and Behavioral Function

  Many clinical studies collect data on neurological function and behavior. Historically, though, the tests available for such studies were expensive, time-consuming, and required specialized training to administer. Many of the most commonly used tests also lacked uniformity. These limitations made it difficult to acquire data and compare it across studies.

  The NIH Toolbox is an integrated set of tools for measuring cognitive, emotional, motor and sensory function. These tools have been validated for use in diverse cultures, ethnic and geographic groups, ages (3-85 years) and study types.

  The toolbox:
  

  
  A grip strength test adapted from the American Society of Hand Therapy is part of the NIH Toolbox.

  • Is low-cost and royalty-free
  • Uses state-of-the art psychometric approaches
  • Uses computer-adaptive testing so that the tests can be calibrated to a subject’s abilities
  • Can be administered within two hours
  • Is adaptable to changes in measurement and technology
  • Is available in English and Spanish

  The toolbox is expected to provide a more complete picture of neurological and behavioral health in large-scale longitudinal studies, epidemiological studies, and clinical trials; and to facilitate cross-study comparisons.