Alliance of Glycobiologists

The Alliance is structured as a partnership for discovery and development by the Tumor Glycomics Laboratories with technical resources and support provided by NIGMS and NHLBI, and clinical validation support from NCI.

Partners

CFG Nature - Functional Glycomics Gateway
Systems Biology Technology Centers
Programs in Excellence in Glycosciences
Early Detection Research Network (EDRN)

Welcome

Welcome to the website for the Alliance of Glycobiologists for Detection of Cancer, a consortium of eight Tumor Glycomics Laboratories and research partners. The Alliance is working to reveal the cancer-related dynamics of complex carbohydrates, and to develop new validated, clinical biomarkers for early cancer detection.

By combining resources and expertise, the Alliance brings an unrivaled strength to this emerging field. Here you will find publications, recent news and media coverage, upcoming meetings and events, contact information and scientific resources from Alliance members.

Mission

The mission of the Alliance is to study structure and function of glycans in relation to cancer development towards developing clinically useful biomarkers for the early detection of cancer by using a variety of approaches and technologies. This charge also requires extensive collaborations across institutions with different skills and facilities to accelerate glycan-based biomarkers to the forefront of NCI's efforts to detect and diagnose cancer at early stages.

The unique needs of the laboratories for technologies embracing carbohydrate chemistry are further supported by programs of:

A Steering Committee (SC) representing all eight Tumor Glycomics Laboratories, representatives from the partnering programs, and program staff from NCI, NIGMS and NHLBI integrates the activities of the Alliance.

In Focus

Identification of potential glycan cancer markers with sialic acid attached to sialic acid and up-regulated fucosylated galactose structures in epidermal growth factor receptor secreted from A431 cell line. Exit Disclaimer Mol Cell Proteomics. 2013 Jan 31. [Epub ahead of print]


The National Academy of Sciences/National Research Council has conducted a study entitled "Assessing the Importance and Impact of Glycomics and Glycosciences." For more information on this study see: http://glyco.nas.edu/ Exit Disclaimer

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Download the Abbreviated Key Findings Exit Disclaimer


More news

Last updated: 02/13/2013
U.S. Department of Health & Human Services National Institutes of Health USA.gov