NIDA Research Monograph, Number 108 [Printed in 1991]
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Download Monograph108.pdf - Cardiovascular Toxicity of Cocaine: Underlying Mechanisms (2.8 MB)
Table of Contents
Preface-----vii
Overview-----1
Pushpa V. Thadani
Maternal-Fetal Cardiovascular System: A Target of Cocaine-----7
James R. Woods, Jr., and Mark A. Plessinger
Pharmacokinetics and Time-Action Profile of Cocaine in Dogs-----28
R. Douglas Wilkerson, Peter N. Temesy-Armos, and Theodore D. Fraker, Jr.
Acute Tolerance to the Chronotropic Effect of Cocaine in Humans-----41
John J. Ambre, Timothy J. Connelly, Tsuen-lh Ruo, and Thomas K. Henthorn
Mechanisms of Cardiac and Vascular Responses to Cocaine-----55
Mark M. Knuepfer, Carrie A. Branch, and Vernon W. Fischer
Cardiovascular Effects of Cocaine in Squirrel Monkeys-----74
Srihari R. Tella, Charles W. Schindler, and Steven R. Goldberg
Role of the Sympathetic Nervous System in the Cardiovascular Effects of Cocaine-----92
Richard A. Gillis, Lisa C. Bachenheimer, Kenneth L. Dretchen, Hashim K. Erzouki, Yvonne M. Hernandez, Rakesh K. Jain, Muskesh K. Jain, Fred E. Kuhn, Jack Quest, and Gary L. Schaer
Cocaine-Induced Myocardial Depression-----110
Theodore D. Fraker, Jr., Peter N. Temesy-Armos, and R. Douglas Wilkerson
Prevalence of Myocardial lschemia in Cocaine Addicts-----116
Koonlawee Nademanee
Cocaine-Induced Myocardial Infarction: Clinical Observations and Pathogenetic Considerations-----121
Jeffrey M. lsner and Saurabh K. Chokshi
Cardiac Electrophysiological Effects of Cocaine in Animal Models-----131
Peter N. Temesy-Armos, Theodore D. Fraker, Jr., and R. Douglas Wilkerson
Effects of Cocaine on Intracellular Calcium Handling in Cardiac and Vascular Smooth Muscle-----139
Cynthia L. Perreault, Kathleen G. Morgan, and James P. Morgan
Cocaine-Induced Changes in the Biochemistry and Morphology of Rabbit Aorta-----154
Ronald O. Langner and Collette L. Bement
Effects of Cocaine on the Physiology of Exercise-----167
Robert K. Conlee, David W. Barnett, K. Patrick Kelly, and Dong Ho Han
Effect of Acute Cocaine Administration on Cardiac and Respiratory Patterning in the Freely Moving Cat-----181
Ronald M. Harper, Rebecca K. Harper, Robert R. Terreberry, Christopher A. Richard, and Robert B. Trelease
Direct and Indirect Morphological Markers of Cocaine Toxicity in the Human Heart-----202
Margaret E. Billinghem
Cocaine-Associated Cardiovascular Disease: Clinical and Pathological Aspects-----220
Renu Virmani
List of NIDA Research Monographs-----230
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