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Neuroscience Methods in Drug Abuse Research



NIDA Research Monograph, Number 62 [Printed in 1985]

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Table of Contents

Preface-----v

THE AUTORADIOGRAPHIC ANALYSIS OF DRUG EFFECTS ON THE NERVOUS SYSTEM

Receptor Mapping in Neuropharmacology by Autoradiography: Some Technical Problems-----1
Michael J. Kuhar, James R. Unnerstall, and Errol B. De Souza

Levels of Quantitative Analysis of Receptor Autoradiography: Technical and Theoretical Issues-----13
Miles Herkenham

ELECTROPHYSIOLOGICAL APPROACHES TO THE STUDY OF DRUG EFFECTS ON THE NERVOUS SYSTEM

Brain-Stimulation Reward: A Model for the Neuronal Bases for Drug-Induced Euphoria-----30
Conan Kornetsky

The Neural Systems Approach to Examining the Actions of Drugs on the Central Nervous System-----51
John K. Chapin, Stephen M. Sorensen, and Donald J. Woodward

Correlating Behavior with Neural Activity: An Approach to Study the Action of Drugs in the Behaving Animal-----63
Sam A. Deadwyler

The Use of Event-Related Potentials in the Study of Alcoholism: Implications for the Study of Drugs of Abuse-----77
B. Porjesz and H. Begleiter

CONSEQUENCES OF CHRONIC DRUG USE

Methamphetamine: Toxicity to Dopaminergic Neurons-----100
Lewis S. Seiden

Molecular Mechanisms of Opiate Tolerance and Dependence in a Clonal Cell Line-----117
Alan K. Louie, Ping-Yee Law, and Horace H. Lob

Consequences of Perinatal Drug Administration on Brain Development: Striatal Opiate Receptors and Dopamine-----129
Sandra Lynn Moon

List of NIDA Research Monographs-----146




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