NIDA Research Monograph, Number 8 [Printed in 1976]
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Download Monograph 8 - Rx :3 x /Week Laam Alternative to Methadone (1.1 MB PDF format)
Table of Contents
Foreword-----V
Robert L. DuPont, M.D.
Introduction-----1
Jack Blaine, M.D. and Pierre Renault, M.D.
The Chemistry of LAAM-----10
Sydney Archer, Ph.D.
PRECLINICAL STUDIES
Pharmacology of LAAM-----15
Sydney Archer, Ph.D.
Toxicology of LAAM-----29
Ms. Ann Wolven and Sydney Archer, Ph.D.
CLINICAL STUDIES
Phase I-----39
Ralph M. Sollod, M.S., and Marcia G. Goldstein, M.A.
Selected Clinical Studies Synopses-----52
Sumnary of Veterans Administration Phase II Cooperative Study for LAAM and Methadone-----94
Walter Ling, M.D. V. Charles Chamvastra, M.D. Samuel C. Kaim, M.D. C. James Klett, Ph.D.
Summary of SAODAP Phase II Cooperative Study of LAAM vs. Methadone-----103
Walter Ling, M.D. C. James Klett, Ph.D. Roderic D. Gillis
Phase III Clinical Study of Levo-Alpha-Acetylmethadol-----109
John A. Whysener, M.D., Ph.D.
The Use of LAAM in Treatment-----112
James Cooper, M.D.
A Clinical Experience with LAAM-----115
Avram Goldstein, M.D.
A LAAM Bibliography
Preclinical-----118
Clinical-----123
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