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All Selected Publications

• Gaillard WD, Kopylev L, Weinstein S, Conry J, Pearl PL, Spanaki MV, Fazilat S, Vezina LG, Dubovsky E, Theodore WH (InPress) 18FDG-PET In Children With New Onset Partial Epilepsy. , Neurology.
• Acosta MT, Munashinge J, Zhang L, Guerron A, Vortmeyer A, Theodore WH (2012) Isolated Seizures in Rats do not Cause Neuronal Injury, Acta Neurologica Scandinavica 125, 30-7.
• Reis J, Cohen LG, Pearl PL, Fritsch B, Jung N, Dustin I, Theodore WH (2012) GABA-(B)-ergic Motor Cortex Dysfunction in SSADH Deficiency, Neurology 79, 47-54.
• Theodore WH, Wiggs EA, Martinez AR et al (2012) Serotonin 1A Receptors, Depression, and Memory in Temporal Lobe Epilepsy, Epilepsia 53, 129-33.
• Hirvonen J, Kreisl W, Fujita M, Dustin I, Khan O, Appel S, Zhang Y, Morse C, Pike VW, Innis RB, Theodore WH (2012) Increased in vivo expression of an inflammatory marker in temporal lobe epilepsy, J Nucl Med 53, 234-40 PMID: 22238156.
• Appel S, Duke ES, Martinez AR, Khan OI, Dustin IM, Reeves-Tyer P, Berl MB, Sato S, Gaillard WD, Theodore WH (2012) Cerebral Blood Flow and fMRI BOLD Auditory Language Activation in Temporal Lobe Epilepsy, Epilepsia 53(4), 631-8.
• Duke ES, Tesfaye M, Berl MM, Walker JE, Ritzl EK, Fasano RE, Conry JA, Pearl PL, Sato S, Theodore WH, Gaillard WD (2012) The effect of seizure focus on regional language processing areas, Epilepsia 53(6), 1044-50.
• Theodore WH, Martinez AR, Khan OI, LIew CJ, Auh S, Dustin IM, Heiss J, Sato S (2012) PET Imaging of Serotonin 1A Receptors and Cerebral Glucose Metabolism for Temporal Lobectomy, J Nucl Med Sep;53(9), 1375-82.
• Finegersh A, Avedissian C, Shamim S, Dustin I, Thompson PM, Theodore WH (2011) Bilateral Hippocampal Atrophy in Temporal Lobe Epilepsy: Effect of Depressive Symptoms and Febrile Seizures, Epilepsia 52(4), 689-97.
• Gaillard WD, MM Berl MM, Duke ES, Ritzl E, Miranda S, Liew C, Finegersh A, A Martinez A, Dustin I, Sato S, Theodore WH (2011) fMRI Language Dominance and FDG-PET Hypometabolism, Neurology 76(15), 1322-9.
• Gaillard WD, Cross HJ, Duncan JS, Stefan H, Theodore WH (2011) Epilepsy Imaging Study Guideline Criteria: Commentary on Diagnostic Testing Study Guidelines & Practice Parameters, Epilepsia 52, 1750-6.
• Granata T, Cross H, Theodore W, Avanzini G (2011) Immune-mediated epilepsies, Epilepsia 52 Suppl 3:5-11.
• Bae EH, Theodore WH, Fregni F, Cantello R, Pascual-Leone A (2011) An estimated placebo effect of repetitive transcranial magnetic stimulation in epilepsy, Epilepsy Behav 20(2), 355-9.
• Acosta MT, Munasinghe J, Pearl PL, Gupta M, Finegersh A, Gibson KM, Theodore WH (2010) Cerebellar Atrophy in Human and Murine SSADH Deficiency, J Child Neurol 25, 1457-61.
• Munasinghe JO, Acosta MT, Banks M, Heffer A, Silva AC, Koretsky A, Theodore WH (2010) Arterial Spin Labeling Demonstrates that Focal Amygdalar Glutamatergic Agonist Infusion Leads to Rapid Diffuse Cerebral Activation Acta Neurol Scand, 121:209-16 .
• Suarez RO, Golby A, Whalen S, Sato S, Theodore WH, Kufta CV, Devinsky O, Balish M, Bromfield EB (2010) Contributions to singing ability by the posterior portion of the superior temporal gyrus of the non-language-dominant hemisphere: First evidence from subdural cortical stimulation, Wada testing, and fMRI, Cortex 46, 343-53.
• Mbwana J, Berl M, Ritzl ER, Rosenberger L, Mayo J, Weinstein S, Conry J, Pearl PL, Shamim S, Moore EN, Sato S, Vezina LG, Theodore WH Gaillard WD (2009) Limitations to Plasticity of Language Network Reorganization in Localization Related Epilepsy, Brain 132, 347-56.
• Pearl PL, Gibson KM, Quezado Z,Dustin I, Taylor J, Trzcinski S, Schreiber J, Forester K, Reeves-Tyer P, Liew C, Shamim S, Herscovitch P, Carson R, Butman J, Theodore WH (2009) Decreased GABA-A Binding on FMZ-PET in Succinic Semialdehyde Dehydrogenase (SSADH) Deficiency, Neurology 73, 423-9 .
• Shamim S, Hasler G, Liew C, Sato S, Theodore WH (2009) Temporal Lobe Epilepsy, Depression, and Hippocampal Volume, Epilepsia 50, 1067-71.
• Shamim S, Edythe Wiggs E, Heiss J, Sato S, Liew C, Solomon J, Theodore WH (2009) Temporal Lobectomy: Resection Volume, Neuropsychological Effects and Seizure Outcome, Epilepsy and Behav 16, 311-4 .
• Theodore WH, Epstein L, Gaillard WD, Shinnar S, Wainwright MS, Jacoboson S (2008) Human Herpes Virus 6B: A possible Role in Epilepsy?, Epilepsia 49, 1828-37 .
• Fotheringham J, Donati D, Akhyani N, Vortmeyer A, Heiss JD, Williams E, Weinstein S, Bruce DA, Gaillard WD, Sato S, Theodore WH, Jacobson S. (2007) Detection of Human Herpesvirus-6B DNA and Antigen in Primary Astrocyte Cultures from Mesial Temporal Lobe Epilepsy Brain Resections., PLoS Med 4(5), e180.
• Theodore WH, Hasler G, Giovacchini G, Kelley K, Reeves-Tyer P, Herscovitch P, Drevets W. (2007) Reduced Hippocampal 5HT1A PET Receptor Binding and Depression in Temporal Lobe Epilepsy., Epilepsia 48, 1526-30.
• Hasler G, Bonwetsch R, Giovacchini G, Toczek MT, Bagic A, Luckenbaugh DA, Drevets WC, Theodore WH. (2007) 5-HT1A receptor binding in temporal lobe epilepsy patients with and without major depression., Biological Psychiatry 62(11), 1258-64.
• Gaillard WD, Berl MM, Moore EA, Ritzl EK, Rosenberger LR, Weinstein SL, Conry JA, Pearl PL, Ritter FF, Sato S, Vezina LG, Vaidya CJ, Wiggs E, Fratalli C, Risse G, Ratner NB, Giooa G, Theodore WH. (2007) Atypical Language in Lesional and Non-lesional Complex Partial Epilepsy., Neurology 69(18), 1761-71.
• Fotheringham J, Donati D, Akhyani N, Vortmeyer A, Heiss JD, Williams E, Weinstein S, Bruce DA, Gaillard WD, Sato S, Theodore WH, Jacobson S (2007) Detection of Human Herpesvirus-6B DNA and Antigen in Primary Astrocyte Cultures from Mesial Temporal Lobe Epilepsy Brain Resections, PLoS Med 4:e180.
• Theodore WH, Hasler G, Giovacchini G, Kelley K, Reeves-Tyer P, Herscovitch P, Drevets W (2007) . Reduced Hippocampal 5HT1A PET Receptor Binding and Depression in Temporal Lobe Epilepsy, Epilepsia 48, 1526-30 .
• Hasler G, Bonwetsch R, Giovacchini G, Toczek MT, Bagic A, Luckenbaugh DA, Drevets WC, Theodore WH (2007) 5-HT1A receptor binding in temporal lobe epilepsy patients with and without major depression, Biological Psychiatry 62, 1258-64 .
• Harden CL, Huff JS, Schwartz T, Zimmerman RD, Weinstein S, Foltin JC, Theodore WH. (2007) Neuroimaging in the emergency patient presenting with seizure, Neurology 69(18), 1772-80.
• Giovacchini G, Toczek MT, MD Bonwetsch R, Bagic A, Lang L, Fraser C, Reeves-Tyer P, Herscovitch P, Eckelman WC, Carson RE, Theodore WH (2005) 5-HT1a receptors are reduced in temporal lobe epilepsy after partial volume correction, J Nucl Med 46, 1128-35.
• Theodore WH, Kelley K, Toczek MT, Gaillard WD. (2004) Epilepsy Duration, Febrile Seizures, and Cerebral Glucose Metabolism, Epilepsia 45, 276-279.
• Theodore WH, De Carli C, Gaillard WD. (2003) Total cerebral volume is reduced in patients with localization-related epilepsy and a history of complex febrile seizures, Arch Neurol 60, 250-252.
• Donati D, Akhyani N, Fogdell-Hahn A, Cermelli C, Cassiani Ingoni R, Vortmeyer A, Heiss JD, Cogen P, Gaillard WD, S. Sato S, Theodore WH, Jacobson S. (2003) Detection of Human Herpesvirus 6 (HHV-6) in Mesial Temporal Lobe Epilepsy Surgical Brain Resections, Neurology 61, 1405-1411.
• Toczek MT, Carson RE, Lang L , Ma Y, Spanaki MV, Der MG, Fazilat S, Fazilat S, Kopylev L, Herscovitch P, Eckelman WC, Theodore WH. (2003) PET Imaging of 5-HT1A Receptor Binding in Patients with Temporal Lobe Epilepsy, Neurology 2003, 749-756.
• Xu B, Grafman J, Gaillard WD, Spanaki S, Ishii K, Balsamo L, Makale M, Theodore WH. (2002) Neuroimaging reveals automatic speech coding during perception of written word meaning, Neuroimage 2, 859-870.
• Theodore WH, Hunter K, Chen R, Vega-Bermudez F, Boroojerdi B, Reeves-Tyer R, Werhahn K, Kelley KR, Cohen L. (2002) Transcranial Magnetic Stimulation for the Treatment of Seizures: A Controlled Study. , Neurology 59, 560-562.
• Xu B, Grafman J , Gaillard WD, Ishii K, Vega-Bermudez F, Pietrini P, Reeves-Tyer P, DiCamillo P, Theodore WH. (2001) Conjoint and Extended Neural Networks for the Computation of Speech Codes: The Neural Basis of Selective Impairment in Reading Words and Pseudowords, Cerebral Cortex 11, 267-77.
• Frattali CM, Liow K, Craig GH, Korenman LM, Makhlouf F, Sato S, Biesecker L, Theodore WH (2001) Cognitive Deficits in Children with Gelastic Seizures and Hypothalamic Hamartoma, Neurology 57, 43-6.
• Theodore WH, Gaillard WD, DeCarli C, Bhatia S, Hatta J. (2001) Hippocampal volume and glucose metabolism in temporal lobe epileptic foci, Epilepsia 42, 130-3.
• Gaillard WD, Hertz-Pannier L, Mott SH, Barnett AS, LeBihan D, Theodore WH (2000) Functional Anatomy of Cognitive Development: fMRI of Verbal Fluency in Children and Adults, Neurology 54, 180-185.
• Spanaki MV, Siegel H, Kopylev L, Fazilat S, Dean A, Liow K, Ben Menachem E, Gaillard W, Theodore WH. (1999) The Effect of Vigabatrin (g- vinyl gaba) on Cerebral Blood Flow and Metabolism., Neurology 53, 1518-22.
• Hunter KE, Blaxton TA, Bookheimer SY, Figlozzi C, Gaillard WD, Grandin C, Anyanwu A, Theodore WH (1999) 15O Water Positron Emission Tomography in Language Localization: A Study Comparing PET Visual and Computerized Region of Interest Analysis with the Wada test. , Annals of Neurology 45, 662-5.
• Theodore WH, Bhatia S, Hatta J, Fazilat S, DeCarli C, Bookheimer S, Gaillard WD (1999) Hippocampal Atrophy, Epilepsy Duration, and Febrile Seizures in Patients with Partial Seizures, Neurology 52, 132-6.
• DeCarli C, Hatta J, Fazilat S, Fazilat S, Gaillard WD and Theodore WH (1998) Extratemporal Atrophy in patients with Complex Partial Seizures of Left Temporal Origin, Annals of Neurology 43, 41-45.
• Theodore WH, Porter RJ, Albert P, et al (1994) The Secondary Generalized Tonic-Clonic Seizure: a Videotape Analysis, Neurology 44, 1403-1408.
• Theodore WH, Sato S, Kufta C, et al (1992) Temporal lobectomy for uncontrolled seizures: the role of positron emission tomography, Ann Neurol 32, 789-794.
• Theodore WH, Porter RJ, Raubertas RF (1987) Seizures during barbiturate withdrawal: relation to blood level, Ann Neurol 22, 644-647.
• Theodore WH, Porter RJ (1983) Removal of sedative-hypnotic antiepileptic drugs from the regimens of patients with intractable epilepsy, Ann Neurol 13, 320-324.
• Ketter TA, Malow BA, Flamini R, White SR, Post RM, Theodore WH (1194) Anticonvulsant withdrawal-emergent psychopathology, Neurology 44, 55-61.

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