This study examined the association of the impairing effects of multiple medication use, drug/drug interactions, and drug/disease interactions on motor vehicle crashes in individuals age 50 years and older. This study examined two databases: (1) the National Ambulatory Medical Care Survey (NAMCS) survey database, and (2) the PharMetrics database to determine the relative frequency of various combinations of medications used by those who have experienced motor vehicle crashes (MVCs) and those who have not. This study suggest that both the kind and number of medication exposures, and the characteristics of diseases/disorders present among study subjects are associated with an increase in risk for MVCs among older adults.
