RPL gene family

Genes in the RPL family provide instructions for making some of the approximately 80 different ribosomal proteins, which are components of cellular structures called ribosomes. Ribosomes process the cell's genetic instructions to create new proteins.

Each ribosome is made up of two parts (subunits) called the large and small subunits. The subunits each consist of multiple ribosomal proteins and RNA, a chemical cousin of DNA. The proteins produced from members of the RPL gene family are found in the large subunit.

The specific functions of the individual ribosomal proteins within the large subunit are unclear. Some ribosomal proteins are involved in the assembly or stability of ribosomes. Others help carry out the ribosome's main function of building new proteins. Studies suggest that some ribosomal proteins may have other functions, such as participating in chemical signaling pathways within the cell, regulating cell division, and controlling the self-destruction of cells (apoptosis).