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Investigator Profiles

Mark N. Polizzotto, M.B.B.S., BMedSc

Mark N. Polizzotto, M.B.B.S., BMedSc

HIV and AIDS Malignancy Branch
Retroviral Disease Section
Assistant Clinical Investigator

National Cancer Institute
Building 10 - Magnuson Clinical Center,
Room 6N106
10 Center Drive
Bethesda, MD 20892

Phone: 301-402-1541
mark.polizzotto@nih.gov


Dr. Polizzotto completed his medical degree at the University of Western Australia, including training in laboratory research at the Walter and Eliza Hall Institute of Medical Research, leading to a bachelor of medical science from the University of Melbourne. He then completed specialty training in internal medicine at St. Vincent’s Hospital Melbourne and the Peter MacCallum Cancer Center and subspecialty training in hematology and hematopathology at the Alfred Hospital Melbourne, leading to fellowships of the Royal Australasian College of Physicians and the Royal College of Pathologists of Australasia. He then received further subspecialty training in the HIV/AIDS Malignancy Branch of the Center for Cancer Research at the National Cancer Institute (NCI), including a Ph.D. jointly at NCI and the University of Melbourne.

His research focuses on understanding the pathophysiology of viral malignancies, particularly those related to Kaposi sarcoma herpesvirus/human herpesvirus 8, using this knowledge to inform development of new therapies with an emphasis on immunomodulatory and antiviral approaches and to investigate novel imaging strategies for these malignancies.

Dr. Polizzotto's Clinical Trial(s):

NCI’s Center for Cancer Research (CCR) is currently conducting the following trial(s) for patients with HIV/AIDS-associated cancers and related diseases and multicentric Castleman disease and associated cancers. Click on the trial(s) below for additional details, including a summary of primary eligibility, study outline, and information on how to contact the study team directly.

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