National Toxicology Program

Ali SF (2012). Amphetamine-like stimulants hit the headlines. Archives of toxicology 86(8):1153-4.
Full-Text: http://dx.doi.org/10.1007/s00204-012-0880-9

Anderson SE, Franko J, Anderson KL, Munson AE, Lukomska E and Meade BJ (2012). Immunotoxicity and allergic potential induced by topical application of dimethyl carbonate (DMC) in a murine model. Journal of immunotoxicology
Full-Text: http://dx.doi.org/10.3109/1547691x.2012.691124

Annab LA, Bortner CD, Sifre MI, Collins JM, Shah RR, Dixon D, Karimi Kinyamu H and Archer TK (2012). Differential responses to retinoic acid and endocrine disruptor compounds of subpopulations within human embryonic stem cell lines. Differentiation; research in biological diversity
Full-Text: http://dx.doi.org/10.1016/j.diff.2012.07.006

Attene-Ramos M, Huang R, Sakamuru S, Witt K, Tice R, Austin C and Xia M (2012). Toxicity Assessment of Environmental Chemicals Using a Quantitative High-Throughput Screening Approach. Environmental and molecular mutagenesis 53(S29-S29.
Full-Text: http://dx.doi.org/10.1002/em.21734

Baldwin RL, Chelonis JJ, Prunty PK and Paule MG (2012). The use of an incremental repeated acquisition task to assess learning in children. Behavioural Processes 91(1):103-114.
Full-Text: http://dx.doi.org/10.1016/j.beproc.2012.06.004

Barchowsky A, Buckley LA, Carlson GP, Fitsanakis VA, Ford SM, Genter MB, Germolec DR, Leavens TL, Lehman-McKeeman LD, Safe SH, Sulentic CEW and Eidemiller BJ (2012). The Toxicology Education Summit: Building the Future of Toxicology Through Education. Toxicological Sciences 127(2):331-338.
Full-Text: http://dx.doi.org/10.1093/toxsci/kfs111

Birnbaum LS (2012). Is Supersize More than Just Too Much Food? Environmental health perspectives 120(6):A223-A224.
Full-Text: http://dx.doi.org/10.1289/ehp.1205200

Birnbaum LS (2012). Environmental Chemicals: Evaluating Low-Dose Effects. Environmental health perspectives 120(4):A143-A144.
Full-Text: http://dx.doi.org/10.1289/ehp.1205179

Boudreau MD, Mellick P, Olson G, Felton R, Thorn B and Beland F (2012). Clear Evidence of Carcinogenic Activity by a Whole Leaf Extract of Aloe barbadenis Miller (Aloe vera) in F344/N Rats. Toxicological sciences : an official journal of the Society of Toxicology
Full-Text: http://dx.doi.org/10.1093/toxsci/kfs275

Brunssen SH, Moy SS, Toews AD, McPherson CA and Harry GJ (2012). Interleukin-6 (IL-6) receptor/IL-6 fusion protein (Hyper IL-6) effects on the neonatal mouse brain: Possible role for IL-6 trans-signaling in brain development and functional neurobehavioral outcomes. Brain, behavior, and immunity
Full-Text: http://dx.doi.org/10.1016/j.bbi.2012.08.017

Bucher JR (2012). Regulatory Forum Opinion Piece: Tox21 and Toxicologic Pathology. Toxicologic pathology
Full-Text: http://dx.doi.org/10.1177/0192623312450632

Casey W (2012). Validating High-throughput Test Methods for Tox21; the Technology Has Changed, but the Objective Remains the Same. In Vitro Cellular & Developmental Biology-Animal 48(13-14.
Full-Text: http://dx.doi.org/10.1007/s11626-012-9500-5

Chan PC and Huff J (2012). Hexane fraction of american ginseng suppresses colitis and colon cancer--letter. Cancer prevention research (Philadelphia, Pa.) 5(7):982.
Full-Text: http://dx.doi.org/10.1158/1940-6207.capr-12-0079

Chelonis J, Aaron H, Belk G, Castro J, Baldwin S, Sutton A and Paule M (2012). Effects of anxiety on motivation in children as measured by progressive ratio task performance. Neurotoxicology and teratology 34(3):381-381.
Full-Text: http://dx.doi.org/10.1016/j.ntt.2012.05.041

Chelonis J, Osborn S, Glenn M and Paule M (2012). Comparison of delayed matching-to-sample performance in children and adult rhesus monkeys. Neurotoxicology and teratology 34(3):369-369.
Full-Text: http://dx.doi.org/10.1016/j.ntt.2012.05.005

Cho HY, van Houten B, Wang X, Miller-Degraff L, Fostel J, Gladwell W, Perrow L, Panduri V, Kobzik L, Yamamoto M, Bell DA and Kleeberger SR (2012). Targeted Deletion of Nrf2 Impairs Lung Development and Oxidant Injury in Neonatal Mice. Antioxidants & redox signaling
Full-Text: http://dx.doi.org/10.1089/ars.2011.4288

Chu IM, Michalowski AM, Hoenerhoff M, Szauter KM, Luger D, Sato M, Flanders K, Oshima A, Csiszar K and Green JE (2012). GATA3 inhibits lysyl oxidase-mediated metastases of human basal triple-negative breast cancer cells. Oncogene 31(16):2017-2027.
Full-Text: http://dx.doi.org/10.1038/onc.2011.382

Corton JC, Bushel PR, Fostel J and O'Lone RB (2012). Sources of variance in baseline gene expression in the rodent liver. Mutation Research-Genetic Toxicology and Environmental Mutagenesis 746(2):104-112.
Full-Text: http://dx.doi.org/10.1016/j.mrgentox.2011.12.017

Cupul-Uicab LA, Skjaerven R, Haug K, Travlos GS, Wilson RE, Eggesbo M, Hoppin JA, Whitworth KW and Longnecker MP (2012). Exposure to Tobacco Smoke in Utero and Subsequent Plasma Lipids, ApoB and CRP among Adult Women in the MoBa Cohort. Environmental health perspectives
Full-Text: http://dx.doi.org/10.1289/ehp.1104563

da Costa GG, Jacob CC, Von Tungeln LS, Hasbrouck NR, Olson GR, Hattan DG, Reimschuessel R and Beland FA (2012). Dose-response assessment of nephrotoxicity from a twenty-eight-day combined-exposure to melamine and cyanuric acid in F344 rats. Toxicology and applied pharmacology 262(2):99-106.
Full-Text: http://dx.doi.org/10.1016/j.taap.2012.04.031

Dahm MM, Evans DE, Schubauer-Berigan MK, Birch ME and Fernback JE (2012). Occupational Exposure Assessment in Carbon Nanotube and Nanofiber Primary and Secondary Manufacturers. Annals of Occupational Hygiene 56(5):542-556.
Full-Text: http://dx.doi.org/10.1093/annhyg/mer110

Di X, Andrews DM, Tucker CJ, Yu L, Moore AB, Zheng X, Castro L, Hermon T, Xiao H and Dixon D (2012). A high concentration of genistein down-regulates activin A, Smad3 and other TGF-beta pathway genes in human uterine leiomyoma cells. Experimental & molecular medicine 44(4):281-92.
Full-Text: http://dx.doi.org/10.3858/emm.2012.44.4.024

Ding W, Petibone DM, Latendresse JR, Pearce MG, Muskhelishvili L, White GA, Chang CW, Mittelstaedt RA, Shaddock JG, McDaniel LP, Doerge DR, Morris SM, Bishop ME, Manjanatha MG, Aidoo A and Heflich RH (2012). In vivo genotoxicity of furan in F344 rats at cancer bioassay doses. Toxicology and applied pharmacology 261(2):164-71.
Full-Text: http://dx.doi.org/10.1016/j.taap.2012.03.021

Dixon D, Di X, Andrews DMK, Tucker CJ, Yu L, Moore AB, Zheng X, Castro L, Hermon T and Xiao H (2012). A high concentration of genistein down-regulates activin a, Smad3 and other TGF-β pathway genes in human uterine leiomyoma cells. Experimental and Molecular Medicine 44(4):281-292.
Full-Text: http://dx.doi.org/10.3858/emm.2012.44.4.024

Dixon D, Reed CE, Moore AB, Gibbs-Flournoy EA, Hines EP, Wallace EA, Stanko JP, Lu Y, Jefferson WN, Newbold RR and Fenton SE (2012). Histopathologic changes in the uterus, cervix and vagina of immature CD-1 mice exposed to low doses of perfluorooctanoic acid (PFOA) in a uterotrophic assay. Reproductive toxicology (Elmsford, N.Y.) 33(4):506-12.
Full-Text: http://dx.doi.org/10.1016/j.reprotox.2011.10.011

Dorea JG, Fenton SE, LaKind JS and Berlin CM (2012). Researching chemicals in human milk can be conducted without discouraging breastfeeding. Bosnian Journal of Basic Medical Sciences 12(2):137-138.
Full-Text: http://www.ncbi.nlm.nih.gov/pubmed?term=22642600

Draper DW, Gowdy KM, Madenspacher JH, Wilson RH, Whitehead GS, Nakano H, Pandiri AR, Foley JF, Remaley AT, Cook DN and Fessler MB (2012). ATP Binding Cassette Transporter G1 Deletion Induces IL-17-Dependent Dysregulation of Pulmonary Adaptive Immunity. Journal of Immunology 188(11):5327-5336.
Full-Text: http://dx.doi.org/10.4049/jimmunol.1101605

Drew CH, Pettibone KG, O'Fallon LR, Collman GW and Birnbaum LS (2012). Measuring partnership activities: partnerships in environmental public health evaluation metrics manual. Environmental health perspectives 120(7):a261-2.
Full-Text: http://dx.doi.org/10.1289/ehp.1205512

Du MY, Yang XJ, Hartman JA, Cooke PS, Doerge DR, Ju YH and Helferich WG (2012). Low-dose dietary genistein negates the therapeutic effect of tamoxifen in athymic nude mice. Carcinogenesis 33(4):895-901.
Full-Text: http://dx.doi.org/10.1093/carcin/bgs017

Ellis JM, Paul DS, DePetrillo MA, Singh BP, Malarkey DE and Coleman RA (2012). Mice Deficient in Glycerol-3-Phosphate Acyltransferase-1 Have a Reduced Susceptibility to Liver Cancer. Toxicologic pathology 40(3):513-521.
Full-Text: http://dx.doi.org/10.1177/0192623311432298

Endres SM, Green BJ, Henneberger PK, Germolec DR, Bledsoe TA, Beezhold DH, London SJ, Alavanja MC, Beane Freeman LE and Hoppin JA (2012). Fungal and atopic sensitization are low among farmers in the Agricultural Health Study. The Journal of allergy and clinical immunology 130(1):267-270 e1.
Full-Text: http://dx.doi.org/10.1016/j.jaci.2012.04.018

Fenton SE (2012). Early Life Environmental Exposures: Lifelong Impact on Mammary Gland Development and Function. Birth Defects Research Part a-Clinical and Molecular Teratology 94(5):306-306.
Full-Text: http://onlinelibrary.wiley.com/doi/10.1002/bdra.23023/abstract

Fox DA, Grandjean P, De Groot D and Paule MG (2012). Developmental origins of adult diseases and neurotoxicity: Epidemiological and experimental studies. NeuroToxicology 33(4):810-816.
Full-Text: http://dx.doi.org/10.1016/j.neuro.2011.12.016

Fox JT, Sakamuru S, Huang RL, Teneva N, Simmons SO, Xia MH, Tice RR, Austin CP and Myung K (2012). Reply to Kojo: Mechanisms of antioxidant-induced DNA damage. Proceedings of the National Academy of Sciences of the United States of America 109(30):E2029-E2029.
Full-Text: http://dx.doi.org/10.1073/pnas.1207795109

Fox JT, Sakamuru S, Huang RL, Teneva N, Simmons SO, Xia MH, Tice RR, Austin CP and Myung K (2012). High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death. Proceedings of the National Academy of Sciences of the United States of America 109(14):5423-5428.
Full-Text: http://dx.doi.org/10.1073/pnas.1114278109

Gamboa da Costa G, Jacob CC, Von Tungeln LS, Hasbrouck NR, Olson GR, Hattan DG, Reimschuessel R and Beland FA (2012). Dose-response assessment of nephrotoxicity from a twenty-eight-day combined-exposure to melamine and cyanuric acid in F344 rats. Toxicology and applied pharmacology 262(2):99-106.
Full-Text: http://dx.doi.org/10.1016/j.taap.2012.04.031

Gao XH, Wang Q, Wang J, Wang CS, Lu L, Gao R, Huan F, Dixon D and Xiao H (2012). Expression of calmodulin in germ cells is associated with fenvalerate-induced male reproductive toxicity. Archives of toxicology 86(9):1443-1451.
Full-Text: http://dx.doi.org/10.1007/s00204-012-0825-3

Gu Q, Schmued LC, Sarkar S, Paule MG and Raymick B (2012). One-step labeling of degenerative neurons in unfixed brain tissue samples using Fluoro-Jade C. Journal of neuroscience methods 208(1):40-3.
Full-Text: http://dx.doi.org/10.1016/j.jneumeth.2012.04.012

Guo LW, Wu Q, Green B, Nolen G, Shi L, Losurdo J, Deng H, Bauer S, Fang JL and Ning B (2012). Cytotoxicity and inhibitory effects of low-concentration triclosan on adipogenic differentiation of human mesenchymal stem cells. Toxicology and applied pharmacology 262(2):117-23.
Full-Text: http://dx.doi.org/10.1016/j.taap.2012.04.024

Hall J, Haas KL and Freedman JH (2012). Role of MTL-1, MTL-2, and CDR-1 in mediating cadmiumsensitivity in Caenorhabditis elegans. Toxicological Sciences 128(2):418-426.
Full-Text: http://dx.doi.org/10.1093/toxsci/kfs166

Hanley KW, Viet SM, Hein MJ, Carreón T and Ruder AM (2012). Exposure to o-Toluidine, Aniline, and nitrobenzene in a rubber chemical manufacturing plant: A retrospective exposure assessment update. Journal of Occupational and Environmental Hygiene 9(8):478-490.
Full-Text: http://dx.doi.org/10.1080/15459624.2012.693836

Hansen DK, George NI, White GE, Pellicore LS, Abdel-Rahman A and Fabricant D (2012). Physiological effects following administration of Citrus aurantium for 28 days in rats. Toxicology and applied pharmacology 261(3):236-47.
Full-Text: http://dx.doi.org/10.1016/j.taap.2012.04.006

Harper M and Ashley K (2012). Preliminary Studies on the Use of Acid-Soluble Cellulose Acetate Internal Capsules for Workplace Metals Sampling and Analysis. Journal of Occupational and Environmental Hygiene 9(7):D125-D129.
Full-Text: http://dx.doi.org/10.1080/15459624.2012.691354

Harper M, Lee EG, Slaven JE and Bartley DL (2012). An inter-laboratory study to determine the effectiveness of procedures for discriminating amphibole asbestos fibers from amphibole cleavage fragments in fiber counting by phase-contrast microscopy. The Annals of occupational hygiene 56(6):645-59.
Full-Text: http://dx.doi.org/10.1093/annhyg/mer123

Harrington JM, Boyd WA, Smith MV, Rice JR, Freedman JH and Crumbliss AL (2012). Amelioration of metal-induced toxicity in caenorhabditis elegans: Utility of chelating agents in the bioremediation of metals. Toxicological Sciences 129(1):49-56.
Full-Text: http://dx.doi.org/10.1093/toxsci/kfs191

He W, Zhou YT, Wamer WG, Boudreau MD and Yin JJ (2012). Mechanisms of the pH dependent generation of hydroxyl radicals and oxygen induced by Ag nanoparticles. Biomaterials 33(30):7547-55.
Full-Text: http://dx.doi.org/10.1016/j.biomaterials.2012.06.076

He Z, He B, Behrle BL, Fejleh MPC, Cui L, Paule MG and Greenfield LJ (2012). Ischemia-Induced Increase in Microvascular Phosphodiesterase 4D Expression in Rat Hippocampus Associated with Blood Brain Barrier Permeability: Effect of Age. ACS Chemical Neuroscience 3(6):428-432.
Full-Text: http://dx.doi.org/10.1021/cn2001156

He Z, Paule MG and Ferguson SA (2012). Low oral doses of bisphenol A increase volume of the sexually dimorphic nucleus of the preoptic area in male, but not female, rats at postnatal day 21. Neurotoxicology and teratology 34(3):331-7.
Full-Text: http://dx.doi.org/10.1016/j.ntt.2012.03.004

Heltshe SL, Lubin JH, Koutros S, Coble JB, Ji BT, Alavanja MCR, Blair A, Sandler DP, Hines CJ, Thomas KW, Barker J, Andreotti G, Hoppin JA and Freeman LEB (2012). Using multiple imputation to assign pesticide use for non-responders in the follow-up questionnaire in the Agricultural Health Study. Journal of Exposure Science and Environmental Epidemiology 22(4):409-416.
Full-Text: http://dx.doi.org/10.1038/jes.2012.31

Hines CJ, Hopf NB, Deddens JA, Silva MJ and Calafat AM (2012). Occupational exposure to diisononyl phthalate (DiNP) in polyvinyl chloride processing operations. International archives of occupational and environmental health 85(3):317-25.
Full-Text: http://dx.doi.org/10.1007/s00420-011-0674-z

Hobbs CA, Chhabra RS, Recio L, Streicker M and Witt KL (2012). Genotoxicity of styrene-acrylonitrile trimer in brain, liver, and blood cells of weanling F344 rats. Environmental and molecular mutagenesis 53(3):227-238.
Full-Text: http://onlinelibrary.wiley.com/doi/10.1002/em.21680/abstract

Hobbs CA, Morgan DL, Shepard K, Price HC, Kissling GE, Shockley KR, Recio L, Witt KL and French JE (2012). Population Variation in Micronucleus Response to Inhaled Benzene in Diversity Outbred (J:DO) Mice. Environmental and molecular mutagenesis 53(S26-S26.
Full-Text: http://dx.doi.org/10.1002/em.21734

Hooth MJ, Nyska A, Fomby LM, Vasconcelos DY, Vallant M, Devito MJ and Walker NJ (2012). Repeated dose toxicity and relative potency of 1,2,3,4,6,7-hexachloronaphthalene (PCN 66) 1,2,3,5,6,7-hexachloronaphthalene (PCN 67) compared to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) for induction of CYP1A1, CYP1A2 and thymic atrophy in female Harlan Sprague-Dawley rats. Toxicology 301(1-3):85-93.
Full-Text: http://dx.doi.org/10.1016/j.tox.2012.07.005

Hoppin JA, Long S, Umbach DM, Lubin JH, Starks SE, Gerr F, Thomas K, Hines CJ, Weichenthal S, Kamel F, Koutros S, Alavanja M, Beane Freeman LE and Sandler DP (2012). Lifetime organophosphorous insecticide use among private pesticide applicators in the Agricultural Health Study. Journal of Exposure Science and Environmental Epidemiology
Full-Text: http://dx.doi.org/10.1038/jes.2012.79

Hussain S, Al-Nsour F, Rice AB, Marshburn J, Yingling B, Ji Z, Zink JI, Walker NJ and Garantziotis S (2012). Cerium dioxide nanoparticles induce apoptosis and autophagy in human peripheral blood monocytes. ACS nano 6(7):5820-9.
Full-Text: http://dx.doi.org/10.1021/nn302235u

Inselman AL, Nakamura N, White G, Harrouk W, McIntyre B, Foster P and Hansen DK (2012). Potential Reproductive and Developmental Toxicity of Oxybenzone: A Dose-Finding Study. Birth Defects Research Part a-Clinical and Molecular Teratology 94(5):349-349.
Full-Text: http://onlinelibrary.wiley.com/doi/10.1002/bdra.23023/abstract

Ji ZY, Weldon RH, Marchetti F, Chen H, Li GL, Xing CH, Kurtovich E, Young S, Schmid TE, Waidyanatha S, Rappaport S, Zhang LP and Eskenazi B (2012). Comparison of aneuploidies of chromosomes 21, X, and Y in the blood lymphocytes and sperm of workers exposed to benzene. Environmental and molecular mutagenesis 53(3):218-226.
Full-Text: http://dx.doi.org/10.1002/em.21683

Jiang R, French JE, Stober VP, Kang-Sickel JCC, Zou F and Nylander-French LA (2012). Single-Nucleotide Polymorphisms Associated with Skin Naphthyl-Keratin Adduct Levels in Workers Exposed to Naphthalene. Environmental health perspectives 120(6):857-864.
Full-Text: http://dx.doi.org/10.1289/ehp.1104304

Kanungo J, Cuevas E, Guo X, Lopez AG, Ramirez-Lee MA, Trickler W, Paule MG and Ali SF (2012). Nicotine alters the expression of molecular markers of endocrine disruption in zebrafish. Neuroscience letters
Full-Text: http://dx.doi.org/10.1016/j.neulet.2012.08.027

Karmakar A, Iancu C, Bartos DM, Mahmood MW, Ghosh A, Xu Y, Dervishi E, Collom SL, Khodakovskaya M, Mustafa T, Watanabe F, Biris AR, Zhang YB, Ali SF, Casciano D, Hassen S, Nima Z and Biris AS (2012). Raman spectroscopy as a detection and analysis tool for in vitro specific targeting of pancreatic cancer cells by EGF-conjugated, single-walled carbon nanotubes. Journal of Applied Toxicology 32(5):365-375.
Full-Text: http://dx.doi.org/10.1002/jat.1742

Kaufmann W, Bolon B, Bradley A, Butt M, Czasch S, Garman RH, George C, Groters S, Krinke G, Little P, McKay J, Narama I, Rao D, Shibutani M and Sills R (2012). Proliferative and Nonproliferative Lesions of the Rat and Mouse Central and Peripheral Nervous Systems. Toxicologic pathology 40(4):87-157.
Full-Text: http://dx.doi.org/10.1177/0192623312439125

Koivisto C, Flake GP, Kolenda-Roberts H, Masinde T, Kissling GE, Sills RC and Hoenerhoff MJ (2012). Immunohistochemical investigation of F344/N rat islet cell tumors from national toxicology program studies. Toxicologic pathology 40(5):751-63.
Full-Text: http://dx.doi.org/10.1177/0192623312441407

Koturbash I, Simpson NE, Beland FA and Pogribny IP (2012). Alterations in histone H4 lysine 20 methylation: implications for cancer detection and prevention. Antioxidants & redox signaling 17(2):365-74.
Full-Text: http://dx.doi.org/10.1089/ars.2011.4370

Kuempel ED, Castranova V, Geraci CL and Schulte PA (2012). Development of risk-based nanomaterial groups for occupational exposure control. Journal of Nanoparticle Research 14(9):1-15.
Full-Text: http://dx.doi.org/10.1007/s11051-012-1029-8

Kuempel ED, Geraci CL and Schulte PA (2012). Risk assessment and risk management of nanomaterials in the workplace: translating research to practice. The Annals of occupational hygiene 56(5):491-505.
Full-Text: http://annhyg.oxfordjournals.org/content/56/5/491.long

Landrigan PJ, Lambertini L and Birnbaum LS (2012). A Research Strategy to Discover the Environmental Causes of Autism and Neurodevelopmental Disabilities. Environmental health perspectives 120(7):A258-A260.
Full-Text: http://dx.doi.org/10.1289/ehp.1104285

Lao HC, Akunda JK, Chun KS, Flake GP, Yuspa SH and Langenbach RJ (2012). Genetic ablation of cyclooxygenase-2 in keratinocytes produces a cell autonomous defect in tumor formation. Carcinogenesis
Full-Text: http://dx.doi.org/10.1093/carcin/bgs267

Lawson CC, Rocheleau CM, Whelan EA, Lividoti Hibert EN, Grajewski B, Spiegelman D and Rich-Edwards JW (2012). Occupational exposures among nurses and risk of spontaneous abortion. American journal of obstetrics and gynecology 206(4):327 e1-8.
Full-Text: http://dx.doi.org/10.1016/j.ajog.2011.12.030

Lee T, Lee EG, Kim SW, Chisholm WP, Kashon M and Harper M (2012). Quartz measurement in coal dust with high-flow rate samplers: laboratory study. The Annals of occupational hygiene 56(4):413-25.
Full-Text: http://dx.doi.org/10.1093/annhyg/mer111

Li Y, Chen DH, Yan J, Chen Y, Mittelstaedt RA, Zhang Y, Biris AS, Heflich RH and Chen T (2012). Genotoxicity of silver nanoparticles evaluated using the Ames test and in vitro micronucleus assay. Mutation research 745(1-2):4-10.
Full-Text: http://dx.doi.org/10.1016/j.mrgentox.2011.11.010

Li Y, Couch L, Higuchi M, Fang JL and Guo L (2012). Mitochondrial dysfunction induced by sertraline, an antidepressant agent. Toxicological sciences : an official journal of the Society of Toxicology 127(2):582-91.
Full-Text: http://dx.doi.org/10.1093/toxsci/kfs100

Lin M, Chandramani-Shivalingappa P, Jin H, Ghosh A, Anantharam V, Ali S, Kanthasamy AG and Kanthasamy A (2012). Methamphetamine-induced Neurotoxicity Linked To Ubiquitin-Proteasome System Dysfunction And Autophagy-Related Changes That Can Be Modulated By Protein Kinase C Delta In Dopaminergic Neuronal Cells. Neuroscience 210(308-332.
Full-Text: http://dx.doi.org/10.1016/j.neuroscience.2012.03.004

Lin MIB, Groves WA, Freivalds A, Lee EG and Harper M (2012). Comparison of artificial neural network (ANN) and partial least squares (PLS) regression models for predicting respiratory ventilation: an exploratory study. European Journal of Applied Physiology 112(5):1603-1611.
Full-Text: http://dx.doi.org/10.1007/s00421-011-2118-6

Lock EF, Abdo N, Huang RL, Xia MH, Kosyk O, O'Shea SH, Zhou YH, Sedykh A, Tropsha A, Austin CP, Tice RR, Wright FA and Rusyn I (2012). Quantitative High-Throughput Screening for Chemical Toxicity in a Population-Based In Vitro Model. Toxicological Sciences 126(2):578-588.
Full-Text: http://dx.doi.org/10.1093/toxsci/kfs023

Magnuson ML, Satzger RD, Alcaraz A, Brewer J, Fetterolf D, Harper M, Hrynchuk R, McNally MF, Montgomery M, Nottingham E, Peterson J, Rickenbach M, Seidel JL and Wolnik K (2012). Guidelines for the Identification of Unknown Samples for Laboratories Performing Forensic Analyses for Chemical Terrorism. Journal of Forensic Sciences 57(3):636-642.
Full-Text: http://dx.doi.org/10.1111/j.1556-4029.2011.02014.x

Maldonado PD, Pérez-De La Cruz V, Torres-Ramos M, Silva-Islas C, Lecona-Vargas R, Lugo-Huitrón R, Blanco-Ayala T, Ugalde-Muñiz P, Vázquez-Cervantes GI, Fortoul TI, Ali SF and Santamaría A (2012). Selenium-induced antioxidant protection recruits modulation of thioredoxin reductase during excitotoxic/pro-oxidant events in the rat striatum. Neurochemistry International 61(2):195-206.
Full-Text: http://dx.doi.org/10.1016/j.neuint.2012.05.004

Mann PC, Vahle J, Keenan CM, Baker JF, Bradley AE, Goodman DG, Harada T, Herbert R, Kaufmann W, Kellner R, Nolte T, Rittinghausen S and Tanaka T (2012). International Harmonization of Toxicologic Pathology Nomenclature: An Overview and Review of Basic Principles. Toxicologic pathology 40(4):7-13.
Full-Text: http://dx.doi.org/10.1177/0192623312438738

Manzano C, Hoh E and Simonich SLM (2012). Improved Separation of Complex Polycyclic Aromatic Hydrocarbon Mixtures Using Novel Column Combinations in GCxGC/ToF-MS. Environmental Science & Technology 46(14):7677-7684.
Full-Text: http://dx.doi.org/10.1021/es301790h

Mathias PI, Cheever KL, Hanley KW, Marlow KL, Johnson BC and B'Hymer C (2012). Comparison and evaluation of urinary biomarkers for occupational exposure to spray adhesives containing 1-bromopropane. Toxicology mechanisms and methods 22(7):526-32.
Full-Text: http://dx.doi.org/10.3109/15376516.2012.686536

Maull EA, Ahsan H, Edwards J, Longnecker MP, Navas-Acien A, Pi J, Silbergeld EK, Styblo M, Tseng CH, Thayer KA and Loomis D (2012). Evaluation of the Association between Arsenic and Diabetes: A National Toxicology Program Workshop Review. Environmental health perspectives
Full-Text: http://dx.doi.org/10.1289/ehp.1104579

Mei N, Zhang Y, Chen Y, Guo X, Ding W, Ali SF, Biris AS, Rice P, Moore MM and Chen T (2012). Silver nanoparticle-induced mutations and oxidative stress in mouse lymphoma cells. Environmental and molecular mutagenesis 53(6):409-19.
Full-Text: http://dx.doi.org/10.1002/em.21698

Mercado-Feliciano M, Cora MC, Witt KL, Granville CA, Hejtmancik MR, Fomby L, Knostman KA, Ryan MJ, Newbold R, Smith C, Foster PM, Vallant MK and Stout MD (2012). An ethanolic extract of black cohosh causes hematological changes but not estrogenic effects in female rodents. Toxicology and applied pharmacology 263(2):138-47.
Full-Text: http://dx.doi.org/10.1016/j.taap.2012.05.022

Merrick BA, Auerbach SS, Stockton PS, Foley JF, Malarkey DE, Sills RC, Irwin RD and Tice RR (2012). Testing an aflatoxin B1 gene signature in rat archival tissues. Chemical research in toxicology 25(5):1132-44.
Full-Text: http://dx.doi.org/10.1021/tx3000945

Methner M, Beaucham C, Crawford C, Hodson L and Geraci C (2012). Field Application of the Nanoparticle Emission Assessment Technique (NEAT): Task-Based Air Monitoring During the Processing of Engineered Nanomaterials (ENM) at Four Facilities. Journal of Occupational and Environmental Hygiene 9(9):543-55.
Full-Text: http://dx.doi.org/10.1080/15459624.2012.699388

Miller MA, Tong W, Fan X and Slikker W (2012). 2012 Global Summit on Regulatory Science (GSRS-2012) - Modernizing Toxicology. Toxicological sciences : an official journal of the Society of Toxicology
Full-Text: http://dx.doi.org/10.1093/toxsci/kfs254

North KP, Mackay DM, Kayne JS, Petersen D, Rasa E, Rastegarzadeh L, Holland RB and Scow KM (2012). In Situ Biotreatment of TBA with Recirculation/Oxygenation. Ground Water Monitoring and Remediation 32(3):52-62.
Full-Text: http://dx.doi.org/10.1111/j.1745-6592.2011.01390.x

Pandiri AR, Sills RC, Ziglioli V, Ton TV, Hong HH, Lahousse SA, Gerrish KE, Auerbach SS, Shockley KR, Bushel PR, Peddada SD and Hoenerhoff MJ (2012). Differential Transcriptomic Analysis of Spontaneous Lung Tumors in B6C3F1 Mice: Comparison to Human Non-Small Cell Lung Cancer. Toxicologic pathology
Full-Text: http://dx.doi.org/10.1177/0192623312447543

Parham F, Wise A, Axelrad DA, Guyton KZ, Portier C, Zeise L, Thomas Zoeller R and Woodruff TJ (2012). Adverse effects in risk assessment: modeling polychlorinated biphenyls and thyroid hormone disruption outcomes in animals and humans. Environmental research 116(74-84.
Full-Text: http://dx.doi.org/10.1016/j.envres.2012.04.003

Partin SN, Connell KA, Schrader S, Lacombe J, Lowe B, Sweeney A, Reutman S, Wang A, Toennis C, Melman A, Mikhail M and Guess MK (2012). The Bar Sinister: Does Handlebar Level Damage the Pelvic Floor in Female Cyclists? The journal of sexual medicine 9(5):1367-1373.
Full-Text: http://dx.doi.org/10.1111/j.1743-6109.2012.02680.x

Paule M, Zhang X, Newport G, Liu SL, Liu F, Callicott R, Berridge M, Apana S, Hanig J, Slikker W and Wang C (2012). L-carnitine attenuates anesthetic-induced increases in a marker of glial activation in the developing monkey brain. Neurotoxicology and teratology 34(3):375-375.
Full-Text: http://dx.doi.org/10.1016/j.ntt.2012.05.023

Petibone D, Kulkarni R, Chang CW, Chen J, Churchwell M and Morris S (2012). Evaluation of p53 Genotype on Gene Expression and O-6-ethylguanine Levels in the Cerebrum from Male C57BL/6 Mice Exposed to ENU. Environmental and molecular mutagenesis 53(S52-S52.
Full-Text: http://dx.doi.org/10.1002/em.21734

Pleil JD, Blount BC, Waidyanatha S and Harper M (2012). Establishing exposure science as a distinct scientific discipline. Journal of Exposure Science and Environmental Epidemiology 22(4):317-319.
Full-Text: http://dx.doi.org/10.1038/jes.2012.5

Qu W, Pi J and Waalkes MP (2012). Metallothionein blocks oxidative DNA damage in vitro. Archives of toxicology
Full-Text: http://dx.doi.org/10.1007/s00204-012-0927-y

Qu W, Tokar EJ, Kim AJ, Bell MW and Waalkes MP (2012). Chronic cadmium exposure in vitro causes acquisition of multiple tumor cell characteristics in human pancreatic epithelial cells. Environmental health perspectives 120(9):1265-71.
Full-Text: http://www.ncbi.nlm.nih.gov/pubmed?term=22626610

Ramot Y, Vered M, Malarkey DE, Hooth MJ, Painter JT, Dayan D, Clayton N, Masinde T and Nyska A (2012). Immunohistochemical Features of 3,3 ',4,4 '-Tetrachloroazobenzene-Induced Rat Gingival Lesions. Toxicologic pathology 40(4):577-592.
Full-Text: http://dx.doi.org/10.1177/0192623311436185

Ray DM, Myers PH, Painter JT, Hoenerhoff MJ, Olden K and Roberts JD (2012). Inhibition of transforming growth factor-beta-activated kinase-1 blocks cancer cell adhesion, invasion, and metastasis. British journal of cancer 107(1):129-36.
Full-Text: http://dx.doi.org/10.1038/bjc.2012.214

Riediker M, Schubauer-Berigan MK, Brouwer DH, Nelissen I, Koppen G, Frijns E, Clark KA, Hoeck J, Liou SH, Ho SF, Bergamaschi E and Gibson R (2012). A Road Map Toward a Globally Harmonized Approach for Occupational Health Surveillance and Epidemiology in Nanomaterial Workers. Journal of occupational and environmental medicine / American College of Occupational and Environmental Medicine
Full-Text: http://dx.doi.org/10.1097/JOM.0b013e31826e27f1

Roberts RA, Wallis R, Ren J, van der Laan JW, Sausen PJ and Slikker W (2012). What It Means to Be Global. Toxicological Sciences 127(1):313-314.
Full-Text: http://dx.doi.org/10.1093/toxsci/kfs079

Sakamuru S, Li X, Attene-Ramos MS, Huang RL, Lu JM, Shou L, Shen M, Tice RR, Austin CP and Xia MH (2012). Application of a homogenous membrane potential assay to assess mitochondrial function. Physiological Genomics 44(9):495-503.
Full-Text: http://dx.doi.org/10.1152/physiolgenomics.00161.2011

Sarsour EH, Kalen AL, Xiao Z, Veenstra TD, Chaudhuri L, Venkataraman S, Reigan P, Buettner GR and Goswami PC (2012). Manganese Superoxide Dismutase Regulates a Metabolic Switch during the Mammalian Cell Cycle. Cancer Research 72(15):3807-3816.
Full-Text: http://dx.doi.org/10.1158/0008-5472.can-11-1063

Satoh M, Chan EKL, Ho LA, Rose KM, Parks CG, Cohn RD, Jusko TA, Walker NJ, Germolec DR, Whitt IZ, Crockett PW, Pauley BA, Chan JYF, Ross SJ, Birnbaum LS, Zeldin DC and Miller FW (2012). Prevalence and sociodemographic correlates of antinuclear antibodies in the United States. Arthritis and Rheumatism 64(7):2319-2327.
Full-Text: http://dx.doi.org/10.1002/art.34380

Schecter A, Malik-Bass N, Calafat AM, Kato K, Colacino JA, Gent TL, Hynan LS, Harris TR, Malla S and Birnbaum L (2012). Polyfluoroalkyl Compounds in Texas Children from Birth through 12 Years of Age. Environmental health perspectives 120(4):590-594.
Full-Text: http://dx.doi.org/10.1289/ehp.1104325

Schecter A, Szabo DT, Miller J, Gent TL, Malik-Bass N, Petersen M, Paepke O, Colacino JA, Hynan LS, Robert Harris T, Malla S and Birnbaum LS (2012). Hexabromocyclododecane (HBCD) stereoisomers in U.S. food from Dallas, Texas. Environmental health perspectives 120(9):1260-1264.
Full-Text: http://www.ncbi.nlm.nih.gov/pubmed?term=22647707

Schulte PA, Kuempel ED, Zumwalde RD, Geraci CL, Schubauer-Berigan MK, Castranova V, Hodson L, Murashov V, Dahm MM and Ellenbecker M (2012). Focused actions to protect carbon nanotube workers. American journal of industrial medicine 55(5):395-411.
Full-Text: http://dx.doi.org/10.1002/ajim.22028

Shen GF, Tao S, Wei SY, Zhang YY, Wang R, Wang B, Li W, Shen HZ, Huang Y, Chen YC, Chen H, Yang YF, Wang W, Wang XL, Liu WX and Simonich SLM (2012). Emissions of Parent, Nitro, and Oxygenated Polycyclic Aromatic Hydrocarbons from Residential Wood Combustion in Rural China. Environmental Science & Technology 46(15):8123-8130.
Full-Text: http://dx.doi.org/10.1021/es301146v

Shiao YH, Leighty RM, Wang CJ, Ge X, Crawford EB, Spurrier JM, McCann SD, Fields JR, Fornwald L, Riffle L, Driver C, Kasprzak KS, Quinones OA, Wilson RE, Travlos GS, Alvord WG and Anderson LM (2012). Molecular and organismal changes in offspring of male mice treated with chemical stressors. Environmental and molecular mutagenesis 53(5):392-407.
Full-Text: http://dx.doi.org/10.1002/em.21701

Shimada H, Hashiguchi T, Yasutake A, Waalkes MP and Imamura Y (2012). Sexual dimorphism of cadmium-induced toxicity in rats: involvement of sex hormones. Archives of toxicology 86(9):1475-1480.
Full-Text: http://dx.doi.org/10.1007/s00204-012-0844-0

Shin EJ, Duong CX, Nguyen XKT, Li Z, Bing GY, Bach JH, Park DH, Nakayama K, Ali SF, Kanthasamy AG, Cadet JL, Nabeshima T and Kim HC (2012). Role of oxidative stress in methamphetamine-induced dopaminergic toxicity mediated by protein kinase C delta. Behavioural Brain Research 232(1):98-113.
Full-Text: http://dx.doi.org/10.1016/j.bbr.2012.04.001

Shockley KR (2012). A three-stage algorithm to make toxicologically relevant activity calls from quantitative high throughput screening data. Environmental health perspectives 120(8):1107-15.
Full-Text: http://dx.doi.org/10.1289/ehp.1104688

Shukla SJ, Huang R, Simmons SO, Tice RR, Witt KL, Vanleer D, Ramabhadran R, Austin CP and Xia M (2012). Profiling environmental chemicals for activity in the antioxidant response element signaling pathway using a high throughput screening approach. Environmental health perspectives 120(8):1150-1156.
Full-Text: http://dx.doi.org/10.1289/ehp.1104709

Simpson NE, Tryndyak VP, Beland FA and Pogribny IP (2012). An in vitro investigation of metabolically sensitive biomarkers in breast cancer progression. Breast cancer research and treatment 133(3):959-68.
Full-Text: http://dx.doi.org/10.1007/s10549-011-1871-x

Slikker W, Zhang X, Newport GD, Paule MG, Liu F, Berridge MS, Kabalka G and Wang C (2012). Assessment of Developmental Exposure to Pediatric Anesthetics Using MicroPET Imaging. Birth Defects Research Part a-Clinical and Molecular Teratology 94(5):330-330.
Full-Text: http://onlinelibrary.wiley.com/doi/10.1002/bdra.23023/abstract

Sprando RL, Reimschuessel R, Stine CB, Black T, Olejnik N, Scott M, Keltner Z, Bandele O, Ferguson M, Nemser SM, Tkachenko A, Evans E, Crosby T, Woodling K, Loukotkova L and da Costa GG (2012). Timing and route of exposure affects crystal formation in MEL and cyanuric exposed male and female rats: Gavage vs. feeding. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Full-Text: http://dx.doi.org/10.1016/j.fct.2012.07.051

Stokes W, McFarland R, Kulpa-Eddy J, Gatewood D, Levis R, Halder M, Pulle G, Kojima H, Casey W, Gaydamaka A, Miller T, Brown K, Lewis C, Chapsal JM, Bruckner L, Gairola S, Kamphuis E, Rupprecht CE, Wunderli P, McElhinney L, De Mattia F, Gamoh K, Hill R, Reed D, Doelling V, Johnson N, Allen D, Rinckel L and Jones B (2012). Report on the international workshop on alternative methods for human and veterinary rabies vaccine testing: State of the science and planning the way forward. Biologicals : journal of the International Association of Biological Standardization 40(5):369-81.
Full-Text: http://dx.doi.org/10.1016/j.biologicals.2012.07.005

Surh I, Behl M, Elmore SA and Chhabra RS (2012). Comparative dermal toxicity of dicyclohexylcarbodiimide and diisopropylcarbodiimide in rodents. Cutaneous and ocular toxicology 31(3):177-87.
Full-Text: http://dx.doi.org/10.3109/15569527.2011.629384

Swartz CD, Hobbs CA, Lentz C, Garibaldi P, Green A, Recio L and Witt KL (2012). 2-Nitroethanol, but Not Related Nitroalcohols, Is Weakly Mutagenic in Bacteria and Negative for Chromosomal and DNA Damage. Environmental and molecular mutagenesis 53(S57-S57.
Full-Text: http://dx.doi.org/10.1002/em.21734

Szabo D, Shah R, Sumner S and Birnbaum L (2012). Systems biology approach for better understanding of mechanisms of neurodevelopment toxicity: A case study using the major flame retardant HBCD. Neurotoxicology and teratology 34(3):379-379.
Full-Text: http://dx.doi.org/10.1016/j.ntt.2012.05.036

Tobón-Velasco JC, Vázquez-Victorio G, MacÍas-Silva M, Cuevas E, Ali SF, Maldonado PD, González-Trujano ME, Cuadrado A, Pedraza-Chaverr J and Santamaría A (2012). S-allyl cysteine protects against 6-hydroxydopamine-induced neurotoxicity in the rat striatum: Involvement of Nrf2 transcription factor activation and modulation of signaling kinase cascades. Free Radical Biology and Medicine 53(5):1024-1040.
Full-Text: http://dx.doi.org/10.1016/j.freeradbiomed.2012.06.040

Trempus CS, Flake GP, Kissling GE, Stober V, Zhuo L, Kimata K and Garantziotis S (2012). Dysregulated wound healing in inter-alpha-trypsin inhibitor deficient mice. Journal of Investigative Dermatology 132(S137-S137.
Full-Text: http://dx.doi.org/10.1038/jid.2012.91

Tryndyak VP, Latendresse JR, Montgomery B, Ross SA, Beland FA, Rusyn I and Pogribny IP (2012). Plasma microRNAs are sensitive indicators of inter-strain differences in the severity of liver injury induced in mice by a choline- and folate-deficient diet. Toxicology and applied pharmacology 262(1):52-9.
Full-Text: http://dx.doi.org/10.1016/j.taap.2012.04.018

Wang J, Lu J, Mook RA, Zhang M, Zhao S, Barak LS, Freedman JH, Lyerly HK and Chen W (2012). The insecticide synergist piperonyl butoxide inhibits hedgehog signaling: Assessing chemical risks. Toxicological Sciences 128(2):517-523.
Full-Text: http://dx.doi.org/10.1093/toxsci/kfs165

Whirledge S, Dixon D and Cidlowski JA (2012). Glucocorticoids regulate gene expression and repress cellular proliferation in human uterine leiomyoma cells. Hormones & cancer 3(3):79-92.
Full-Text: http://dx.doi.org/10.1007/s12672-012-0103-0

Whitworth KW, Haug LS, Baird DD, Becher G, Hoppin JA, Skjaerven R, Thomsen C, Eggesbo M, Travlos G, Wilson R, Cupul-Uicab LA, Brantsaeter AL and Longnecker MP (2012). Perfluorinated compounds in relation to birth weight in the Norwegian Mother and Child Cohort Study. American journal of epidemiology 175(12):1209-16.
Full-Text: http://dx.doi.org/10.1093/aje/kwr459

Wise A, Parham F, Axelrad DA, Guyton KZ, Portier C, Zeise L, Zoeller RT and Woodruff TJ (2012). Upstream adverse effects in risk assessment: A model of polychlorinated biphenyls, thyroid hormone disruption and neurological outcomes in humans. Environmental research 117(90-99.
Full-Text: http://dx.doi.org/10.1016/j.envres.2012.05.013

Yildirim E, Carey MA, Card JW, Dietrich A, Flake GP, Zhang Y, Bradbury JA, Rebolloso Y, Germolec DR, Morgan DL, Zeldin DC and Birnbaumer L (2012). Severely blunted allergen-induced pulmonary Th2 cell response and lung hyperresponsiveness in type 1 transient receptor potential channel-deficient mice. American journal of physiology. Lung cellular and molecular physiology 303(6):L539-49.
Full-Text: http://dx.doi.org/10.1152/ajplung.00389.2011

Yoo M, Kim D, Choi KY, Chae JC, Zylstra GJ and Kim E (2012). Draft Genome Sequence and Comparative Analysis of the Superb Aromatic-Hydrocarbon Degrader Rhodococcus sp Strain DK17. Journal of Bacteriology 194(16):4440-4440.
Full-Text: http://dx.doi.org/10.1128/jb.00844-12

Yucesoy B, Johnson VJ, Lummus ZL, Kissling GE, Fluharty K, Gautrin D, Malo JL, Cartier A, Boulet LP, Sastre J, Quirce S, Germolec DR, Tarlo SM, Cruz MJ, Munoz X, Luster MI and Bernstein DI (2012). Genetic variants in antioxidant genes are associated with diisocyanate-induced asthma. Toxicological Sciences 129(1):166-173.
Full-Text: http://dx.doi.org/10.1093/toxsci/kfs183

Zhan L, Zhang H, Zhang Q, Woods CG, Chen Y, Xue P, Dong J, Tokar EJ, Xu Y, Hou Y, Fu J, Yarborough K, Wang A, Qu W, Waalkes MP, Andersen ME and Pi J (2012). Regulatory role of KEAP1 and NRF2 in PPARγ expression and chemoresistance in human non-small-cell lung carcinoma cells. Free Radical Biology and Medicine 53(4):758-768.
Full-Text: http://dx.doi.org/10.1016/j.freeradbiomed.2012.05.041

Zhang Q, Gamboa da Costa G, Von Tungeln LS, Jacob CC, Brown RP and Goering PL (2012). Urinary biomarker detection of melamine- and cyanuric Acid-induced kidney injury in rats. Toxicological sciences : an official journal of the Society of Toxicology 129(1):1-8.
Full-Text: http://dx.doi.org/10.1093/toxsci/kfs182

Zhao Y, Xia Q, Gamboa da Costa G, Yu H, Cai L and Fu PP (2012).
Full Structure Assignments of Pyrrolizidine Alkaloid DNA Adducts and Mechanism of Tumor Initiation. Chemical research in toxicology
Full-Text: http://dx.doi.org/10.1021/tx300292h