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ARDS Clinical Network Prospective, Randomized, Multicenter Trial of Aerosolized Albuterol versus Placebo for the Treatment of Acute Lung Injury (ALTA)

Study Type: Clinical Trial
Prepared on November 17, 2009
Consent: Proprietary Consent
Commercial Use Restrictions: No
Collection Type: Proprietary Study - See bottom of this webpage for request information


This study was a prospective, randomized trial of aerosolized Albuterol vs. Placebo to test the safety and efficacy of aerosolized beta-2 adrenergic agonist therapy for improving clinical outcomes in patients with acute lung injury. Patients were followed for 90 days or until discharge from the hospital to home with unassisted breathing, whichever occurs first. The primary efficacy variable was ventilator-free days to study day 28. This study was stopped for futility after 282 patients.