Carolyn M. Hutter, Ph.D.
Program Director, Host Susceptibility Factors Branch
Contact Information
Epidemiology and Genomics Research Program
Division of Cancer Control and Population Sciences
National Cancer Institute
6130 Executive Blvd., Rm. 5106, MSC 7393
Bethesda, MD 20892-7393
(For express delivery, use Rockville, MD 20852)
telephone: (301) 435-4910
fax: (301) 435-6609
e-mail: huttercm@mail.nih.gov
Interest Areas
Genetic epidemiology, statistical methods, and post-GWAS research
Degrees
Ph.D. - Epidemiology
University of Washington
M.S. - Biostatistics
University of Washington
M.S. - Genetics
Cornell University
B.Sc. - Applied Mathematics-Biology
Brown University
Biography
Dr. Hutter is a Program Director in the Epidemiology and Genomics Research Program's (EGRP) Host Susceptibility Research Branch. Her responsibilities include expanding and managing a portfolio of grants that supports the development and implementation of more sophisticated methods in statistical genetics and genetic epidemiology for studies of complex diseases such as cancer. This will include a focus on the many analytic and computational challenges accompanying the application of next generation sequencing technologies to large scale epidemiology studies.
Prior to joining EGRP, Dr. Hutter was a Senior Staff Scientist in the Cancer Prevention Program at the Fred Hutchinson Cancer Research Center and a Lecturer in the Epidemiology Department at the University of Washington. She earned her doctorate in Epidemiology and her master's in Biostatistics at the University of Washington. She also holds an M.S. in Genetics and a B.S. in Applied Mathematics and Biology. In addition to teaching at the graduate level, Dr. Hutter has volunteered for science education programs that work with junior high and high school students.
Her previous research focused on the role that genetic and environmental factors play in the risk of colorectal cancer, Parkinson's disease, and other complex phenotypes. She has had more than 40 papers published in peer-reviewed journals, including articles stemming from her participation in EGRP's Genetic Associations and Mechanisms in Oncology (GAME-ON) Initiative.
Selected Publications
Hutter CM, Chang-Claude J, Slattery M, Pflugeisen B, Lin Y, Duggan D, Nan H, Lemire M, Rangrej J, Figueiredo J, Jiao S, Harrison T, Liu Y, Chen L, Stelling D, Warnick G, Hoffmeister M, Kury S, Fuchs CS, Giovannucci E, Hazra A, Kraft P, Hunter D, Gallinger S, Zanke B, Brenner H, Frank B, Ma J, Ulrich C, Newcob PA, White E, Kooperberg C, LaCroix A, Prentice R, Jackson R, Schoen R, Chanock S, Berndt S, Hayes R, Caan B, Potter J, Hsu L, Bezieau S, Chan A, Hudson T, Peters U. Characterizing gene-environment interactions for previously identified colorectal cancer susceptibility loci. Cancer Research. 72(8):2036-2044. 2012.
Peters U*, Hutter CM*, Hsu L, Schumacher FR, Conti DV, Carlson CS, Edlund CK, Haile RW, Gallinger S, Zanke BW, Lemire M, Rangrej J, Vijayaraghavan R, Chan AT, Hazra A, Hunter DJ, Ma J, Fuchs CS, Giovannucci EL, Kraft P, Liu Y, Chen L, Jiao S, Makar KW, Taverna D, Gruber SB, Rennert G, Moreno V, Ulrich CM, Woods MO, Green RC, Parfrey PS, Prentice RL, Kooperberg C, Jackson RD, LaCroix AZ, Caan BJ, Hayes RB, Berndt SI, Chanock SJ, Schoen RE, Chang-Claude J, Hoffmeister M, Brenner H, Frank B, Bézieau S, Küry S, Slattery ML, Hopper JL, Jenkins MA, Le Marchand L, Lindor NM, Newcomb PA, Hudson TJ, Duggan DJ, Potter JD, Casey G, on behalf of CCFR and GECCO. Meta-analysis of new genome-wide scans for colorectal cancer risk. Hum Genet. 131(2):217-34. 2012.
*co-first authors who contributed equally to this work.
Hutter CM, Young A, Ochs-Balcom H, Carty C, Wang T, Rohan T, Kooperberg C, Peters U. Replication of breast cancer GWAS susceptibility loci in the Women's Health Initiative African American SHARe study
. Cancer Epidemiol Biomarkers Prev. 20(9): 1950-9. 2011.
Chen LS. Hutter CM. Potter JD. Liu Y, Prentice RL, Peters U, Hsu L. Insights into Colon Cancer Etiology via a Regularized Approach to Gene Set Analysis of GWAS Data. Am J Hum Genet. 86(6):860-71. 2010.
Hutter CM, Samii A, Factor SA, Nutt JG, Higgins DS, Bird TD, Griffith A, Roberts JW, Leis BC, Montimurro JS, Kay DM, Edwards KL, Payami H, Zabetian CP. Lack of evidence for an association between UCHL1 S18Y and Parkinson's disease. Eur J Neurol. 15(2):134-9. 2008.
