Pascale Lepage, Ph.D.
Public Health Advisor, Kelly Scientific Services
Contact Information
Epidemiology and Genomics Research Program
Division of Cancer Control and Population Sciences
National Cancer Institute
6130 Executive Blvd., Rm. 5131A, MSC 7393
Bethesda, MD 20892-7393
(For express delivery, use Rockville, MD 20852)
telephone: (301) 594-3652
fax: (301) 435-6609
e-mail: lepagep@mail.nih.gov
Interest Areas
Molecular biology of lung cancer
Degrees
Ph.D. - Pharmacology
University of Sherbrooke, Québec, Canada
B.Sc. - Biology
McGill University, Québec, Canada
Biography
Dr. Lepage is an employee of Kelly Scientific Services and works as a Public Health Advisor in the Epidemiology and Genomics Research Program’s (EGRP) Host Susceptibility Factors Branch (HSFB). She is assisting with coordination and scientific support (e.g. knowledge synthesis of loci implicated in multiple cancers and complex diseases) of the Genetic Associations and Mechanisms in Oncology (GAME-ON): A Post-Genome Wide Association Initiative.
Before joining EGRP in 2011, Dr. Lepage was a Postdoctoral Visiting Fellow in NCI's Office of Science Planning and Assessment where she worked on the NCI Congressional justification and conducted extensive state cancer legislative database research on cancer prevention and helped facilitate strategic planning retreats for NCI, including EGRP. Dr. Lepage was also a Postdoctoral Fellow in NCI's Laboratory of Cancer Biology and Genetics, where she studied lung cancer. During her Ph.D., Dr. Lepage identified and characterized the molecular determinants involved in the assembly of Transient Receptor Potential Canonical calcium channels (TRPC).
Selected Publications
Decicco-Skinner KL, Trovato EL, Simmons JK, Lepage PK, Wiest JS. Loss of Tumor progression locus 2 (Tpl2) enhances tumorigenesis and inflammation in two-stage carcinogenesis
. Oncogene. 2011; 30(4): 389-397.
Lepage PK, Lussier MP, McDuff FO, Lavigne P, Boulay G. The self-association of two N-terminal interaction domains plays an important role in the tetramerization of TRPC4. Cell Calcium. 2009 Mar; 45(3): 251-259.
