National Library of Medicine TOXMAP Skip Navigation

What data sources does TOXMAP use?

The data found in TOXMAP comes from several providers, including:
  • Toxics Release Inventory (TRI)
    A federal law called the Emergency Planning and Community Right to Know Act (EPCRA) ( requires facilities in certain industries which manufacture, process, or use significant amounts of toxic chemicals, to report annually on their releases of these chemicals. The reports contain information about the types and amounts of toxic chemicals that are released each year to the air, water, land and by underground injection, as well as information on the quantities of toxic chemicals sent to other facilities for further waste management.

    Facilities with ten or more full-time employees that process more than 25,000 pounds in aggregate, or use greater than 10,000 pounds of any one TRI chemical, are required to report releases annually. The US Environmental Protection Agency (EPA) ( maintains this information in a database called the Toxics Release Inventory (TRI) ( The toxics release files on the National Library of Medicine's® (NLM) Toxicology Data Network (TOXNET®) ( come from TRI.

    TOXMAP uses the most current, final TRI data available from the EPA. Data submission deadlines, data entry processes, and data quality control and review all influence the actual date of data release by both the EPA and by TOXMAP.

    A complete list of chemicals currently listed in TOXMAP can be found at A complete list of TRI chemicals required to be reported to the EPA can be found at

    NOTE: At this time, TOXMAP uses reported on-site releases only. Some TRI chemicals have no reported releases, and so will not appear in the TRI release data or in TOXMAP.

    For more information, see the TRI Fact Sheet (

    CERCLIS (Comprehensive Environmental Response, Compensation and Liability Information System) ( is a database maintained by the US Environmental Protection Agency (EPA).

    CERCLIS contains information about Superfund sites, such as the current status of cleanup efforts, cleanup milestones reached, and amounts of liquid and solid media treated at sites on the National Priorities List (NPL) or under consideration for the NPL. The CERCLIS database can be searched at

  • EPA's Facility Registry System (FRS)
    TOXMAP plots the location of TRI facilities using addresses and coordinates from the EPA's Facility Registry System (FRS) ( The FRS is a centrally managed database that identifies facilities, sites or places subject to environmental regulations or of environmental interest.

  • Hazardous Substances Databank® (HSDB)
    HSDB ( contains comprehensive toxicological information on over 4,700 chemicals. Data in HSDB are peer-reviewed, and are derived and referenced from a core set of books, government documents, technical reports and selected primary journal literature. For more information, see the HSDB Fact Sheet (

    TOXLINE® ( is the National Library of Medicine's (NLM) bibliographic database on toxicology, containing over 3 million references to literature on biochemical, pharmacological, physiological, and toxicological effects of drugs and other chemicals. It is composed of articles from PubMed®/MEDLINE® and references from an assortment of specialized journals and other sources. For more information, see the TOXLINE® Fact Sheet.

  • Agency for Toxic Substances and Disease Registry
    The Agency for Toxic Substances and Disease Registry (ATSDR) ( is an agency of the US Department of Health and Human Services. It strives to use the best science, to take responsive public health actions, and to provide trusted health information to prevent harmful exposures and disease related to toxic substances.

  • National Atlas of the United States of America (USGS)
    TOXMAP uses the USGS's National Atlas ( for the following data:

  • National Cancer Institute (NCI)
    TOXMAP uses the NCI's SEER*Stat Database ( for its cancer and disease mortality data. Underlying mortality data provided by the National Center for Health Statistics (NCHS) ( of the Centers for Disease Control and Prevention (CDC) (

  • National Weather Service OST/SEC GIS Map Group
    Map data for US Territories such as Puerto Rico, US Virgin Islands, American Samoa, Guam, Marshall Islands, & Midway come from NOAA's ( National Weather Service OST/SEC GIS Map Group (

  • ESRI
    Data for hospitals, lakes, rivers, and other bodies of water, and for boundaries of Mexico come from ESRI ( Hospital data was derived from the AHA FY2005 data release.

  • GeoGratis
    Data for Canadian boundaries come from GeoGratis (Canadian government) (