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Technologies Available for Licensing from NIH/FDA
| Nucleotide, Deduced Amino Acid Sequence, Isolation And Purification Of Heat-Shock Chlamydial Proteins | | This invention concerns the discovery of a novel gene that encodes the HSP60 protein from Chlamydia trachomatis, referred to as HypB in the application. This immunodominant protein is a major target for Chlamydia trachomatis vaccine development and diagnostics. This gene and protein, or fragments thereof, are useful in the development of both recombinant protein and DNA based vaccines. The recombinant protein or DNA sequence also have potential for the development of diagnostic tes... More... | | Nucleotide And Amino Acid Sequences Of The Four Variable Domains Of The Major Outer Membrane Proteins Of Chlamydia Trachomatis | | Chlamydia trachomatis is the leading sexually transmitted infectious agent in the United States, causing about 10 million new cases per year. It is a major cause of involuntary infertility in women. This invention claims the DNA sequences, and their encoded amino acid sequences, of the four variable domains from the major outer membrane protein (MOMP) of Chlamydia trachomatis, from the serovars Ba, D, E, F, G, H, I, J, K and L3. Serovars D, E, F, G, H, I, J, and K are the most comm... More... | | Chlamydia Vaccine | | Chlamydia trachomatis is an obligate intracellular bacterial pathogen that colonizes and infects oculogenital mucosal surfaces. The organism exists as multiple serovariants that infect millions of people worldwide. Ocular infections cause trachoma, a chronic follicular conjunctivitis that results in scarring and blindness. The World Health Organization estimates that 300–500 million people are afflicted by trachoma, making it the most prevalent form of infectious preventable blindness.... More... |
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Technologies Available for Licensing from Non-Profit Institutions
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