Articles Tagged ‘DNA’

Cancer Genetics in the 21st Century

Illustration of Hyper- and Hypomethylation

The past decade has brought tremendous advances in genetics and molecular biology. In a short time, we have gone from sequencing the genome of a bacterium to sequencing the genome of a human. Polymerase Chain Reaction (PCR) has enabled researchers to take a minute sample of DNA and amplify it a million-fold, and DNA evidence has become the new “fingerprints” of forensic investigations. More recently, gene microchips have made it possible to look at the activity of thousands of genes simultaneously.

A Primer on HPV

Cancer cells

Human papillomavirus (HPV) is now recognized as the major cause of cervical cancer, a disease that kills more than 200,000 women around the world each year. HPV is very common, however, and of the more than 100 types of HPV, fewer than 20 are considered “high-risk” for the development of cancer. The following is a brief guide to HPV, including transmission, incidence, treatment, and its connection to genital warts and cancer.

Bethesda 2001: A Revised System for Reporting Pap Test Results

Cancer cells

Laboratories across the country soon will change the way they communicate with physicians about the 50 million cervical cancer screening tests performed each year in the United States. The revised system, known as the 2001 Bethesda System and published in the April 24, 2002, issue of the Journal of the American Medical Association (JAMA), conveys laboratory findings that help physicians and their patients decide what to do about the abnormalities found on Pap tests.