SCIENTIFIC ADVANCES

Since 2009, several clinical trial results reported findings that will likely change the way patients with acute myeloid leukemia (AML), multiple myeloma, breast cancer as well as children with high-risk neuroblastoma are treated. In addition, the discovery of certain gene alterations in children with acute lymphoblastic leukemia (ALL) has uncovered potential new targets for therapeutic approaches in this disease.

• Improving Outcome for Children with High-Risk Neuroblastoma
• High Dose Chemotherapy Significantly Prolongs Survival for Patients with Acute Myeloid Leukemia
• Lenalidomide for Multiple Myeloma Demonstrated to Significantly Extend Progression-Free Survival
• Disease-Free Breast Cancer Survival Improves When Herceptin is Used With Chemotherapy
• Childhood Cancer TARGET Initiative Acute Lymphoblastic Leukemia Discoveries