National Eye Institute (NEI)

51 Protocols (39 Active Accrual of new subjects, 12 Follow-up of previously enrolled subjects)

 13-EI-0049:

Genetics of Uveal Coloboma

 13-EI-0027:

AMD Phenotype and Genotype Study (APGS)

 12-EI-0203:

Natural History of ABCA4-Related Retinopathies

 12-EI-0134:

A Phase II Randomized Study to Compare Anti-VEGF Agents in the Treatment of Diabetic Macular Edema (CADME)

 12-EI-0119:

Phase II, Randomized, Placebo-Controlled Study for the Evaluation of Finasteride in the Treatment of Chronic Central Serous Chorioretinopathy

 12-EI-0057:

A Phase I/II Study to Investigate Subconjunctival Sirolimus for the Treatment of Active Autoimmune Non-Necrotizing Anterior Scleritis

 12-EI-0042:

NEI Intramural Biorepository for Retinal Diseases

 11-EI-0264:

A Pilot Study for the Evaluation of Minocycline as a Microglia Inhibitor in the Treatment of Central Retinal Vein Occlusions

 11-EI-0263:

A Pilot Study for the Evaluation of Minocycline as a Microglia Inhibitor in the Treatment of Branched Retinal Vein Occlusions

 11-EI-0249:

Pilot Study of the Evaluation of Intravitreal Sirolimus in the Treatment of Bilateral Geographic Atrophy Associated with Age-Related Macular Degeneration

 11-EI-0245:

Generation of Induced Pluripotent Stem (iPS) Cell Lines from Somatic Cells of Participants with Retinal Disease and from Somatic Cells of Matched Controls

 11-EI-0244:

A Pilot Phase I/II Study for the Evaluation of Dextromethorphan as a Microglia Inhibitor in the Treatment of Diabetic Macular Edema (MiDME2)

 11-EI-0173:

The Natural History of Ocular Graft-Versus Host Disease

 11-EI-0147:

Longitudinal Investigation of Dark Adaptation in Participants with Age-Related Macular Degeneration

 11-EI-0124:

Home Vision Monitoring in AREDS2 for Progression to Neovascular AMD Using the Foresee Home Device

 11-EI-0107:

Treatment of Non-infectious Panuveitis, Intermediate and Posterior Uveitis Associated Macular Edema with Intravitreal Methotrexate

 10-EI-0191:

Peptide B27PD (Optiquel(Registered Trademark)) as Corticosteroid-sparing Therapy for Chronic Non-infectious Uveitis (BOOTS)

 10-EI-0169:

Evaluation of Single Nucleotide Polymorphisms (SNPs) in Patients with and without Diabetic Macular Edema

 10-EI-0140:

Genotype-Phenotype Study of Patients with Plaquenil(Registered Trademark)-Induced Retinal Toxicity, with Evaluation of the ABCA4 Gene

 10-EI-0093:

Immunogenetic Mechanisms in Behcet's Disease

 08-EI-0169:

Evaluation and Treatment Protocol for Potential Research Participants with Ocular Diseases

 08-EI-0102:

Screening Study for the Evaluation and Diagnosis of Potential Research Participants

 08-EI-0099:

Epigenetics, Molecular Genetics, and Biomarkers of Degenerative and Inflammatory Ocular Diseases

 08-EI-0043:

Age-Related Eye Disease Study (AREDS) and AREDS2 Follow-Up

 08-EI-0031:

Visual Motor Coordination

 06-EI-0236:

National Ophthalmic Genotyping and Phenotyping Network, Stage 1 - Creation of DNA Repository for Inherited Ophthalmic Diseases

 06-EI-0230:

Family Studies of Uveal Coloboma

 06-EI-0068:

The Vitreous Proteome and Inflammatory Mediators in Ocular Inflammatory Disease

 06-EI-0059:

Clinical and Molecular Studies in Families with Glaucoma and Related Diseases

 06-EI-0058:

Clinical and Molecular Studies in Families with Myopia and Related Diseases

 05-EI-0143:

Molecular Genetics of Retinal Degenerations

 05-EI-0096:

Natural History and Genetic Studies of Usher Syndrome

 04-EI-0008:

Clinical and Molecular Studies in Families with Corneal Dystrophy or Other Inherited Corneal Diseases

 03-EI-0155:

Evaluation of Single Nucleotide Polymorphism (SNP) in Patients with and Subjects without Age-Related Macular Degeneration (AMD)

 03-EI-0123:

Clinical and Molecular Studies in Families with Congenital or Hereditary Cataracts

 03-EI-0122:

Evaluation of Immune Responses to Different Antigens in Non Infectious Ocular Inflammatory Diseases

 03-EI-0033:

X-Linked Juvenile Retinoschisis - Clinical and Molecular Studies

 92-EI-0113:

Immunopathology and Molecular Pathology of Ocular Diseases in Humans

 86-EI-0062:

Trial of Topical Cysteamine in the Treatment of Corneal Cystine Crystal Accumulation in Cystinosis

 12-EI-0168:

A Pilot Study to Investigate Ustekinumab (StelaraTM) for the Treatment of Active Sight-Threatening Uveitis

 12-EI-0167:

A Phase I/II Study of the NT-501 Intraocular Implant Releasing Ciliary Neurotrophic Factor (CNTF) in Participants with CNGB3 Achromatopsia

 12-EI-0013:

Pilot Phase I/II study of the Treatment of Classic Centeral Serous Chorioretinopathy with Topical Interferon Gamma-1b

 11-EI-0012:

Extension Study for the Evaluation of Finasteride in the Treatment of Chronic Central Serous Chorioretinopathy

 10-EI-0098:

A Pilot Study for the Evaluation of Minocycline as a Microglia Inhibitor in the Treatment of Diabetic Macular Edema

 10-EI-0040:

Rituximab for Autoimmune Retinopathy

 10-EI-0016:

Internal Monitoring of Eye Movement in Schizophrenia

 08-EI-0103:

High Speed Indocyanine Green Angiography Findings in Induction/PRN Regimen of Intravitreal Ranibizumab Injection for Neovascular Age-Related Macular Degeneration

 07-EI-0213:

Laboratory of Immunology/National Eye Institute Repository

 07-EI-0145:

Ocular Impact of X Chromosome Karyotype and Sex Hormones in Turner Syndrome and Premature Ovarian Failure

 07-EI-0025:

The Age-Related Eye Disease Study 2 (AREDS2): A Multi-Center, Randomized Trial of Lutein, Zeaxanthin, and Omega-3 Long-Chain Polyunsaturated Fatty Acids (Docosahexaenoic Acid [DHA] and Eicosapentaenoic Acid [EPA]) in Age-Related Macular Degeneration

 06-EI-0050:

Multicenter Uveitis Steroid Treatment (MUST) Trial Protocol

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