Viral MicroRNAs

Our group studies the functions of viral microRNAs in a tumorigenic virus in order to identify pathways instrumental to viral pathogenesis and potentially lead to discovery of novel anti-viral and anti-tumor targets. This work utilizes one of the largest databases of microRNA target expression profiling (microarray and proteomic) and sequence analysis. We have recently completed validation of a number of predicted microRNA target genes. Currently, we have validated over thirty human genes that are targeted by viral microRNAs which are awaiting further study. Some microRNA functions of interest include: immune evasion, cell cycle regulation, and apoptosis.

Candidates must have or plan to have a Ph.D. and/or MD with excellent communication skills and cell culture experience. Post-graduate degrees must be obtained in the last five years. Those with experience with RNAi are desirable.

Please send CV, brief statement of research experience/future interests and contact information for at least three references to Dr. Joseph Ziegelbauer in a single pdf to ziegelbauerjm@mail.nih.gov. Please include "postdoc" in the email subject line.

For more information about the HIV/AIDS Malignancy Branch and The National Cancer Institute, please visit: http://ccr.cancer.gov/staff/staff.asp?profileid=15171

This position is subject to a background investigation. The NIH is dedicated to building a diverse community in its training and employment programs.