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The NCI Center for Cancer Research (CCR) conducts more than 150 cancer clinical trials at the National Institutes of Health (NIH) Clinical Center in Bethesda, Maryland. Cancer clinical trials that take place at the NIH Clinical Center are open to patients with cancer, regardless of where they live in the United States.

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There are 14 clinical trials at NIH that match your search criteria


  • Cancer by type/disease: Brain Tumor (Childhood)

  
Trial and Protocol Number
Brain Tumor
Principal InvestigatorReferral Contact
Phase II
A Phase II Randomized Trial of Lenalidomide in Pediatric Patients With Recurrent, Refractory or Progressive Juvenile Pilocytic Astrocytomas and Optic Pathway Gliomas
NCI-12-C-0136, NCT01553149
Katherine E. Warren
301-496-4256
Linda Ellison
301-496-8009
ellisonl@mail.nih.gov
Phase I/II
PBTC-033 A Phase I/II Study of ABT-888, an Oral Poly(ADP-ribose) Polymerase Inhibitor, and Concurrent Radiation Therapy, Followed by ABT-888 and Temozolomide, in Children With Newly Diagnosed Diffuse Pontine Gliomas (DIPG)
NCI-12-C-0213, NCT01514201
Katherine E. Warren
301-496-4256
Linda Ellison
301-496-8009
ellisonl@mail.nih.gov
Phase I
Phase I and Pharmacokinetic Study of AZD6244 for Recurrent or Refractory Pediatric Low Grade Glioma
NCI-11-C-0191, NCT01386450
Katherine E. Warren
301-496-4256
Linda Ellison
301-496-8009
ellisonl@mail.nih.gov
A Phase I Trial of Lenalidomide and Radiotherapy in Children With Diffuse Intrinsic Pontine Gliomas and High-grade Gliomas
NCI-10-C-0219, NCT01226940
Katherine E. Warren
301-496-4256
Linda Ellison
301-496-8009
ellisonl@mail.nih.gov
An Open Label Dose Escalation Safety Study of Convection-Enhanced Delivery of IL13-PE38QQR in Patients With Progressive Pediatric Diffuse Infiltrating Brainstem Glioma and Supratentorial High-Grade Glioma
NINDS-09-N-0117, NCT00880061
Russell R. Lonser
301-496-5728
Linda Ellison
301-496-8009
ellisonl@mail.nih.gov
No Phase
An Exploratory Study of Biologic and Pathophysiologic Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors
NCI-06-C-0219, NCT00401037
Katherine E. Warren
301-496-4256
Linda Ellison
301-496-8009
ellisonl@mail.nih.gov
A Comparative Study of Pediatric CNS Tumor Activity as Assessed by 18F-FDG PET Imaging and Proton Magnetic Resonance Spectroscopic Imaging (1H-MRSI)
NCI-03-C-0278, NCT00070512
Katherine E. Warren
301-496-4256
Linda Ellison
301-496-8009
ellisonl@mail.nih.gov
Evaluation of the Natural History of Patients With Tumors of the Central Nervous System
NCI-01-C-0070, NCT00458640
Teri Kreisl
301-402-3423
Tracy Cropper
301-402-6298
Toll free: 866-251-9686
tcropper@mail.nih.gov


  
Trial and Protocol Number
Neurofibroma/Neurofibromatosis
Principal InvestigatorReferral Contact
Phase I
A Phase II Study of Everolimus (RAD001) for Children With Neurofibromatosis Type-1 and Chemotherapy-Refractory Radiographic Progressive Low-Grade Gliomas
NCI-12-C-0058, NCT00901849
Katherine E. Warren
301-496-4256
Linda Ellison
301-496-8009
ellisonl@mail.nih.gov


  
Trial and Protocol Number
Pediatric Cancers
Principal InvestigatorReferral Contact
Phase I
A Phase I Study of XL184 (Cabozantinib, IND# 116059) in Children and Adolescents With Recurrent or Refractory Solid Tumors, Including CNS Tumors
NCI-13-C-0042, NCT01709435
Brigitte Widemann
301-496-7387
Pediatric Oncology
301-496-4256
1-877-624-4878 (Toll free)

Phase I Study of Temsirolimus in Combination With Irinotecan and Temozolomide in Children, Adolescents, and Young Adults With Relapsed or Refractory Solid Tumors
NCI-11-C-0053, NCT01141244
Brigitte Widemann
301-496-7387
Pediatric Oncology
301-496-4256
1-877-624-4878 (Toll free)

Phase I Trial and Pharmacokinetic Study of the Oral Platinum Analog Satraplatin in Children and Young Adults With Refractory Solid Tumors Including Brain Tumors
NCI-11-C-0047, NCT01259479
Brigitte Widemann
301-496-7387
Pediatric Oncology
301-496-4256
1-877-624-4878 (Toll free)

A Phase 1/2 Study of PF-02341066, An Oral Small Molecule Inhibitor of Anaplastic Lymphoma Kinase (ALK) and C-Met, in Children With Relapsed/Refractory Solid Tumors and Anaplastic Large Cell Lymphoma
NCI-10-C-0178, NCT01182896
Brigitte Widemann
301-496-7387
Pediatric Oncology
301-496-4256
1-877-624-4878 (Toll free)

No Phase
A Comprehensive Omics Analysis of Pediatric Oncology Solid Tumors and Establishment of a Repository for Related Biological Studies
NCI-10-C-0086, NCT01109394
Javed Khan
301-435-2937
Pediatric Oncology
301-496-4256
1-877-624-4878 (Toll free)



For additional studies that may be appropriate for your disease type, please search under Solid Tumor.

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