International Warfarin Pharmacogenomics Consortium (IWPC) sample sets:
A number of pharmacogenomics research centers have collected data sets relating warfarin dosing to a variety of clinical and genetic parameters including genotypes of CYP2C9 and VKORC1. There is an interest among these groups in sharing their data, in order to possibly arrive at a consensus model for dosing that is consistent with all data sets. For further information regarding the warfarin consortium, please send e-mail to feedback@pharmgkb.org.
IWPC Team
Data Contributors
- Academic Sinica, Taiwan, ROC:
Ming-Ta M. Lee, Yuan-Tsong Chen
- Chang Gung Memorial Hospital, Chang Gung University, Taiwan, ROC:
Ming-Shien Wen
- Hadassah Medical Organization, Israel:
Yoseph Caraco, Idit Achache, Simha Blotnick, Mordechai Muszkat
- Inje University, Korea:
Jae-Gook Shin, Ho-Sook Kim
- Instituto Nacional de Câncer, Brazil:
Guilherme Suarez-Kurtz, Jamila Alessandra Perini, Edimilson A. Silva
- Intermountain Healthcare, USA:
Jeffrey Anderson, Benjamin Horne, John Carlquist
- Marshfield Clinic, USA:
Michael D. Caldwell, Richard L. Berg, James K. Burmester
- National University Hospital, Singapore:
Boon Cher Goh, Soo-Chin Lee
- Newcastle University, United Kingdom:
Farhad Kamali, Elizabeth Sconce, Ann Daly
- University of Alabama, USA:
Nita Limdi
- University of California, San Francisco, USA:
Alan Wu
- University of Florida, USA:
Julie A. Johnson, Taimour Y. Langaee, Hua Feng
- University of Illinois, Chicago, USA:
Larisa Cavallari, Kathryn Momary
- University of Liverpool, United Kingdom:
Munir Pirmohamed, Andrea Jorgensen, Cheng Hok Toh, Paula Williamson
- University of North Carolina, USA:
Howard McLeod, James P. Evans, Karen E. Weck
- University of Pennsylvania, USA:
Stephen Kimmel, Colleen Brensinger
- University of Tokyo and RIKEN, Japan:
Yusuke Nakamura, Taisei Mushiroda
- University of Washington, USA:
David Veenstra, Lisa Meckley, Mark Rieder, Allan Rettie
- Uppsala University, Sweden:
Mia Wadelius, Niclas Eriksson
- Vanderbilt University, USA:
C. Michael Stein, Dan M. Roden, Ute Schwartz, Daniel Kurnik
- Washington University in St. Louis, USA:
Brian Gage, Elena Deych, Petra Lenzini, Charles Eby
- Wellcome Trust Sanger Institute, United Kingdom:
Leslie Y. Chen, Panos Deloukas
Statistical Analysis:
- University of Alabama, USA:
Nita Limdi
- Marshfield Clinic, USA:
Michael D. Caldwell
- North Carolina State University, USA:
Alison Motsinger-Reif
- Stanford University, USA:
Teri E. Klein, Russ B. Altman, Balaji S. Srinivasan
- Uppsala University, Sweden:
Niclas Eriksson
- University of California, San Francisco, USA:
Alan Wu
- University of North Carolina, USA:
Michael Wagner
- University of Florida, USA:
Julie A. Johnson
- University of Pennsylvania, USA:
Stephen Kimmel
- University of Wisconsin-Madison, USA:
David Page, Eric Lantz, Tim Chang
- Vanderbilt University, USA:
Marylyn Ritchie
- Washington University in St. Louis, USA:
Brian Gage, Elena Deych
Genotyping QC of IWPC Samples:
- Academic Sinica, Taiwan, ROC:
Ming-Ta M. Lee, Liang-Suei Lu
Data Curation:
- Stanford University, USA:
Teri E. Klein, Russ B. Altman, Balaji S. Srinivasan
- Washington University in St. Louis, USA:
Elena Deych
Funding Acknowledgements:
- Academic Sinica, Taiwan, ROC:
National Research Program for Genomic Medicine, National Science Council,
Taiwan (National Clinical Core, NSC95-3112-B-001-010 and National Genotyping
Center, NSC95-3112-B -001-011)
- Hadassah Medical Organization, Israel:
Israeli Science Foundation (789/04), United States - Israel Binational Foundation (2003229), Chief Scientist, Ministry of Health (5745)
- Inje University, Korea:
KOSEF / MOST (No. R13-2007-023-00000-0) and Korea Health 21 R&D Project, Ministry of Health and Welfare, Korea (A030001)
- Instituto Nacional de Câncer, Brazil:
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq) and Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ)
- Newcastle University, United Kingdom:
National Health Service (NHS) Executive (Northern & Yorkshire)
- Stanford University, USA:
NIH/NIGMS Pharmacogenetics Research Network and Database (U01GM61374)
- University of Alabama, USA:
NIH/NINDS (K23NS45598-01)
- University of Florida, USA:
NIH/NIGMS Pharmacogenetics Research Network and Database (U01GM074492)
- University of Illinois, Chicago, USA:
the American Association of Colleges of Pharmacy and the American Foundation for Pharmaceutical Education
- University of Liverpool, United Kingdom:
United Kingdom Department of Health
- University of North Carolina, USA:
NIH/NIGMS Pharmacogenetics Research Network and Database (U01GM63340) and
North Carolina Biotechnology Company Multidisciplinary Research Grant (2006-MRG-1117)
- University of Pennsylvania, USA:
NIH (R01HL066176, P20RR020741 and K24HL070936)
- University of Washington, USA:
NIH/NIGMS (GM68797 and GM32165), NIH/NINDS (NS053646), CDC National Office of
Public Health Genomics (NOPHG) Seed Funding, University of Washington Drug Metabolism, Transport and Pharmacogenomics Research (DMTPR) Program
- Uppsala University, Sweden:
Wellcome Trust, Swedish Funding agencies: the Society of Medicine, the Foundation for Strategic Research, the Heart and Lung Foundation, the Söderberg, Thuréus and Selander Foundations and the Clinical Research Support (ALF)
- Vanderbilt University, USA:
NIH/NIGMS Pharmacogenetics Research Network and Database (U01HL65962)
- Washington University in St. Louis, USA:
NIH (R01HL074724 and R01HL71083), American Heart Association
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