PGRN-RIKEN CGM Collaborative Studies Underway
First Set of Studies (RIKEN I)
Second Set of Studies (RIKEN II)
Third Set of Studies (RIKEN III)
Fourth Set of Studies (RIKEN IV)
Fifth Set of Studies (RIKEN V)
Sixth Set of Studies (RIKEN VI)
Seventh Set of Studies (RIKEN VII)
First Set of Studies (RIKEN I)
| Title: |
Gemcitabine and Bevacizumab for Pancreatic Cancer |
| Principal investigators: |
Drs. F. Innocenti, N. Cox, K. Owzar, H. Kindler, K. Giacomini, H. McLeod, M. Ratain, with Dr. Y. Nakamura |
| Approximate number of samples: |
352 |
| |
|
| Title: |
Aromatase Inhibitors for Breast Cancer w/ MA-27 |
| Principal investigators: |
Drs. J. Ingle, R. Weinshilboum, D. Flockhart, V. Stearns, with Dr. T. Mushiroda |
| Approximate number of samples: |
1688 |
| |
|
| Title: |
Drug-induced Long QT Syndrome Genetic Prediction |
| Principal investigators: |
Drs. D. Roden, M. Province, M. Ritchie and A.L. George, with Dr. T. Tanaka |
| Approximate number of samples: |
1000+ |
| |
|
| Title: |
Cyclophosphamide and Doxorubicin/Paclitaxel for Breast Cancer |
| Principal investigators: |
Drs. D. Kroetz, E. Jorgenson, K. Owzar, J. Witte, L. Shulman, H. McLeod, M. Ratain, with Dr. H. Zembutsu |
| Approximate number of samples: |
1984 |
| |
|
| Title: |
International Warfarin PGx Consortium (IWPC) |
| Principal investigators: |
Drs. J. Johnson, D. Roden, M. Caldwell for the International Warfarin Pharmacogenetics Consortium, IWPC, with Dr. T. Mushiroda |
| Approximate number of samples: |
1000 |
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Second Set of Studies (RIKEN II)
| Title: |
Bevacizumab Addition to Prostate Cancer Therapy |
| Principal investigators: |
Drs. McLeod, Ratain, Kroetz, Kelly, Ozwar, Cox, Motsinger-Rief with Dr. Zembutsu |
| Approximate number of samples: |
835 |
| |
|
| Title: |
Tamoxifen/Raloxiphen Adjuvant to Treat Breast Cancer w/ NSABP |
| Principal investigators: |
Drs. Ingle, Wickerham, Schaid, Costantino, Vogel, Paik, Goetz, Flockhart, Wolmark, Weinshilboum with Dr. Zembutsu |
| Approximate number of samples: |
1848 |
| |
|
| Title: |
Inhaled beta-Agonists for Asthma |
| Principal investigators: |
Drs. Weiss, Litonjua, Tantisira, Ritchie with Dr. Tamari |
| Approximate number of samples: |
1121 |
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Third Set of Studies (RIKEN III)
| Title: |
ACE Inhibitors and Andiogedema |
| Principal investigators: |
Drs. N. Brown, D. Roden, S. Williams, C. Ingram, R. Krauss, C. McCarty, with Dr. M. Kubo |
| Approximate number of samples: |
818 |
| |
|
| Title:
| Antiretrovirals for HIV Infection in Uganda |
| Principal investigators: |
Drs. D. Kroetz, D. Bangsberg, J. Martin, P. Hunt, E. Jorgenson, J. Witte, H. McLeod, M. Wagner, with Dr. T. Mushiroda |
| Approximate number of samples: |
500+ |
| |
|
| Title: |
Celecoxib Effectiveness for Colorectal Cancer |
| Principal investigators: |
Drs. M. Bertagnolli, S. Weiss, J. Su, M. Ratain, K. Owzar, with Dr. K. Matsuda |
| Approximate number of samples: |
1660 |
| |
|
| Title: |
Citalopram and Escitalopram for Depression |
| Principal investigators: |
Drs. D. Mrazek, C. Schaefer, D. Schaid, K. Giacomini, and R. Weinshilboum, with Dr. T. Mushiroda |
| Approximate number of samples: |
500+ |
| |
|
| Title: |
AV Nodal Blocking Agents for Atrial Fibrillation |
| Principal investigators: |
Drs. D. Darbar, D. Roden, M. Province, M. Ritchie, H. Okafor, P. Ellinor, S. Kabb, H. Watanabe, with Dr. T. Tanaka |
| Approximate number of samples: |
2000 |
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Fourth Set of Studies (RIKEN IV)
| Title:
| Corticosteroid and Inhaled Short-Acting Beta Agonists and Asthma |
| Principal investigators: |
Drs. S. Weiss, K. Tantisira, A. Litonjua, J. Lasky-Su, with Dr. M. Tamari |
| Approximate number of samples: |
1,041 |
| |
|
| Title: |
Busulfan-Based Chemotherapy and Acute Myelogenous Leukemia |
| Principal investigators: |
Drs. C. Andreadis, K. Giacomini, J. Witte, L. Johnston, S. Baker, M. Relling, M. Baer, D. Kroetz, with Dr. K. Matsuda |
| Approximate number of samples: |
444 |
| |
|
| Title: |
Aromatase Inhibitors and Bone Fractures |
| Principal investigators: |
Drs. P. Goss, D. Schaid, J.-A. Chapman, S. Khosla, L. Shepherd, M. Ellis, V. Stearns, D. Flockhart, R. Weinshilboum, J. Ingle, with Dr. H. Zembutsu |
| Approximate number of samples: |
1,250 |
| |
|
| Title: |
SSRIs and Depression |
| Principal investigators: |
Drs. D. Mrazek, J. Kirchheiner, T. Klein, D. Schaid, R. Altman, K. Giacomini, R. Weinshilboum, with Dr. T. Mushiroda |
| Approximate number of samples: |
2,000 |
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Fifth Set of Studies (RIKEN V)
| Title:
| Colorectal Cancer Pharmacogenetics |
| Principal investigators: |
Drs. H. McLeod, K. Owzar, M. Ratain, A. Venook, P. Friedman, M. Bertagnolli, with Dr. H. Zembutsu |
| Approximate number of samples: |
1,000 |
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Sixth Set of Studies (RIKEN VI)
| Title:
| Pharmacogenomics of Methotrexate Response in Patients with Rheumatoid Arthritis |
| Principal investigators: |
Drs. T. Bongartz, E. Matteson, R. Weinshilboum, B. Fridley, with Dr. Y. Kochi |
| Approximate number of samples: |
1600 |
| |
|
| Title:
| Genetic Determinants of Glycemic Response to Metformin in Type 2 Diabetes |
| Principal investigators: |
Drs. K. Giacomini, D. Roden, C. McCarty, R. Davis, J. Witte, A. Shuldiner, M. Hedderson, N. Iwasaki, with Dr. S. Maeda |
| Approximate number of samples: |
>500 |
| |
|
| Title:
| Pharmacogenetics of Prostacyclin Dosing in Pulmonary Arterial Hypertension |
| Principal investigators: |
Drs. M. Gomberg-Maitland, R. Benza, M. Maitland, N. Cox, with Dr. M. Tamari |
| Approximate number of samples: |
1198 |
| |
|
| Title:
| Genome-Wide Association Study of 5-Lipoxygenase Inhibition in Asthma |
| Principal investigators: |
Drs. K. Tantisira, S. Weiss, A. Litonjua, J. Lasky-Su, W. Qiu, Q. L. Duan, B. Himes, M. McGeachie, A. Wu, S. M. Tse, J. Drazen, J. Lima, with Dr. M. Tamari |
| Approximate number of samples: |
1334 |
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Seventh Set of Studies (RIKEN VII)
| Title:
| A Genome-Wide Association Study in Patients Experiencing Breast Events While Receiving Aromatase Inhibitors for Early Breast Cancer on NCIC CTG Trial MA.27 |
| Principal investigators: |
Drs. M. Ellis, J. Ingle, P. Goss, D. Schaid, J. Chapman, L. Shepherd, R. Weinshilboum with Dr. M. Kubo |
| Approximate number of samples: |
270 |
| |
|
| Title:
| Pharmacogenetic Analysis of the Newly Established First-line Treatment Strategy in Patients with Advanced Ovarian Cancer: Adding Bevacizumab to Standard Carboplatin-Paclitaxel Chemotherapy. |
| Principal investigators: |
Drs. G. Liu, H. MacKay, W. Xu, A. Oza with Dr. K. Matsuda |
| Approximate number of samples: |
492 |
| |
|
| Title:
| Genome-Wide Association Analyses of Pharmacogenomic Loci Associated with Adverse Cardiovascular Outcomes and New-onset Diabetes after Antihypertensive Therapy |
| Principal investigators: |
Drs. R. Cooper-DeHoff, Y. Gong, C. Pepine, S. Padmanabhan, A. Dominiczak, M. Caulfield, with Dr. T. Tanaka |
| Approximate number of samples: |
1690 |
This page last reviewed on March 12, 2012