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Blood and Marrow Transplant Clinical Trials Network (BMT CTN) Treatment for Acute Graft-Versus-Host Disease (BMT CTN 0302)

Parent Study Contact: Alan Howard,
Study Type: Clinical Trial
Prepared on September 14, 2010
Consent: Proprietary Consent
Commercial Use Restrictions: No
Collection Type: Proprietary Study - See bottom of this webpage for request information


This study was a randomized Phase II, four arm treatment trial. Patients with newly diagnosed acute GVHD received corticosteroids plus one of four agents: etanercept, mycophenolate mofetil (MMF), Denileukin Diftitox (ONTAK) or pentostatin. Each agent was assessed for safety and efficacy compared to historical complete response rates to acute GVHD therapy with corticosteroids alone.