Resources and Tools

Clinical Research

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NIH Toolbox for Assessment of Neurological and Behavioral Function
A Blueprint-Funded Resource
  • The NIH Toolbox provides brief, easy-to-administer tests of motor, cognitive, sensory and emotional function.
  • These tests are intended to provide a more complete picture of neurological and behavioral health in large-scale longitudinal studies, epidemiological studies, and clinical trials; and to facilitate valid cross-study comparisons.
  • More information

NIH MRI Study of Normal Brain Development
A Blueprint-Funded Resource
  • A study to collect MRI scans and correlated behavioral data from ~ 500 healthy, typically developing children, from newborn to late adolescence. Imaging modalities include structural MRI, spectroscopy and diffusion tensor imaging.
  • The study will improve our understanding of brain development, provide a control database for studies of childhood psychiatric, developmental and neurological disorders, and may lead to new imaging tools.
  • More information

FNIH Biomarkers Consortium
  • A partnership among the Foundation for NIH (FNIH), government agencies and the private sector, formed to accelerate the development of biomarkers – non-symptomatic changes in the body that indicate a disease process or risk of disease.
  • Researchers seeking assistance with biomarker development for brain disorders may apply to the Consortium's Neuroscience Steering Committee for financial and technical support.

  • Funded by NINDS, NeuroNEXT is a unique clinical trial network open to studies of more than 400 neurological diseases, allowing investigators to more efficiently pursue new therapies based on scientific opportunity.
  • The network has a centralized IRB serving 25 sites, which will allow trials to move faster, without the need to coordinate IRBs at each individual site.
  • It is not necessary to be part of the NeuroNEXT infrastructure to propose and conduct a study within the network.